Circumvention of Mcl-1-dependent drug resistance by simultaneous Chk1 and MEK1/2 inhibition in human multiple myeloma cells
Pei, Xin-Yan, Dai, Yun, Felthousen, Jessica, Chen, Shuang, Takabatake, Yukie, Zhou, Liang, Youssefian, Leena E, Sanderson, Michael W, Bodie, Wesley W, Kramer, Lora B, Orlowski, Robert Z, Grant, Steven
Published in PloS one (04.03.2014)
Published in PloS one (04.03.2014)
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The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo
Dasmahapatra, Girija, Lembersky, Dmitry, Kramer, Lora, Fisher, Richard I., Friedberg, Jonathan, Dent, Paul, Grant, Steven
Published in Blood (03.06.2010)
Published in Blood (03.06.2010)
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Interactions between Bortezomib and Romidepsin and Belinostat in Chronic Lymphocytic Leukemia Cells
YUN DAI, SHUANG CHEN, KRAMER, Lora B, FUNK, Vanessa L, DENT, Paul, GRANT, Steven
Published in Clinical cancer research (15.01.2008)
Published in Clinical cancer research (15.01.2008)
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The IAP antagonist birinapant potentiates bortezomib anti-myeloma activity in vitro and in vivo
Zhou, Liang, Zhang, Yu, Leng, Yun, Dai, Yun, Kmieciak, Maciej, Kramer, Lora, Sharma, Kanika, Wang, Yan, Craun, William, Grant, Steven
Published in Journal of hematology and oncology (07.03.2019)
Published in Journal of hematology and oncology (07.03.2019)
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Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor–induced DNA damage in vitro and in vivo in human multiple myeloma cells
Dai, Yun, Chen, Shuang, Pei, Xin-Yan, Almenara, Jorge A., Kramer, Lora B., Venditti, Charis A., Dent, Paul, Grant, Steven
Published in Blood (15.09.2008)
Published in Blood (15.09.2008)
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CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies
SHUANG CHEN, YUN DAI, RICHEY, Justin D, LARSEN, Dustin G, DENT, Paul, ORLOWSKI, Robert Z, GRANT, Steven, PEI, Xin-Yan, MYERS, Jennifer, LI WANG, KRAMER, Lora B, GARNETT, Mandy, SCHWARTZ, Daniella M, SU, Florence, SIMMONS, Gary L
Published in Cancer research (Chicago, Ill.) (15.08.2012)
Published in Cancer research (Chicago, Ill.) (15.08.2012)
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Cytokinetically quiescent (G0/G1) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2
Pei, Xin-Yan, Dai, Yun, Youssefian, Leena E., Chen, Shuang, Bodie, Wesley W., Takabatake, Yukie, Felthousen, Jessica, Almenara, Jorge A., Kramer, Lora B., Dent, Paul, Grant, Steven
Published in Blood (10.11.2011)
Published in Blood (10.11.2011)
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Bortezomib interacts synergistically with belinostat in human acute myeloid leukaemia and acute lymphoblastic leukaemia cells in association with perturbations in NF‐κB and Bim
Dai, Yun, Chen, Shuang, Wang, Li, Pei, Xin‐Yan, Kramer, Lora B., Dent, Paul, Grant, Steven
Published in British journal of haematology (01.04.2011)
Published in British journal of haematology (01.04.2011)
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Disruption of Src function potentiates Chk1-inhibitor–induced apoptosis in human multiple myeloma cells in vitro and in vivo
Dai, Yun, Chen, Shuang, Shah, Rena, Pei, Xin-Yan, Wang, Li, Almenara, Jorge A., Kramer, Lora B., Dent, Paul, Grant, Steven
Published in Blood (10.02.2011)
Published in Blood (10.02.2011)
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The Three-Substituted Indolinone Cyclin-Dependent Kinase 2 Inhibitor 3-[1-(3H-Imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one (SU9516) Kills Human Leukemia Cells via Down-Regulation of Mcl-1 through a Transcriptional Mechanism
Gao, Ning, Kramer, Lora, Rahmani, Mohamed, Dent, Paul, Grant, Steven
Published in Molecular pharmacology (01.08.2006)
Published in Molecular pharmacology (01.08.2006)
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Cotreatment with Suberanoylanilide Hydroxamic Acid and 17-Allylamino 17-demethoxygeldanamycin Synergistically Induces Apoptosis in Bcr-Abl+ Cells Sensitive and Resistant to STI571 (Imatinib Mesylate) in Association with Down-Regulation of Bcr-Abl, Abrogation of Signal Transducer and Activator of Transcription 5 Activity, and Bax Conformational Change
Rahmani, Mohamed, Reese, Erin, Dai, Yun, Bauer, Cheryl, Kramer, Lora B, Huang, Mei, Jove, Richard, Dent, Paul, Grant, Steven
Published in Molecular pharmacology (01.04.2005)
Published in Molecular pharmacology (01.04.2005)
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The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells
MAGGIO, Sonia C, ROSATO, Roberto R, KRAMER, Lora B, DAI, Yun, RAHMANI, Mohamed, PAIK, David S, CZARNIK, Ann C, PAYNE, Shawn G, SPIEGEL, Sarah, GRANT, Steven
Published in Cancer research (Chicago, Ill.) (01.04.2004)
Published in Cancer research (Chicago, Ill.) (01.04.2004)
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BCL-2 antagonists interact synergistically with bortezomib in DLBCL cells in association with JNK activation and induction of ER stress
Dasmahapatra, Girija, Lembersky, Dmitry, Rahmani, Mohamed, Kramer, Lora, Friedberg, Jonathan, Fisher, Richard I., Dent, Paul, Grant, Steven
Published in Cancer biology & therapy (01.05.2009)
Published in Cancer biology & therapy (01.05.2009)
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Synergistic Interactions between DMAG and Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitors in Bcr/abl+ Leukemia Cells Sensitive and Resistant to Imatinib Mesylate
Nguyen, Tri K, Rahmani, Mohamed, Gao, Ning, Kramer, Lora, Corbin, Amie S, Druker, Brian J, Dent, Paul, Grant, Steven
Published in Clinical cancer research (01.04.2006)
Published in Clinical cancer research (01.04.2006)
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Phase I Trial and Correlative Laboratory Studies of Bryostatin 1 (NSC 339555) and High-Dose 1-B-d-Arabinofuranosylcytosine in Patients with Refractory Acute Leukemia
CRAGG, Louise H, ANDREEFF, Michael, FELDMAN, Eric, ROBERTS, John, MURGO, Anthony, WINNING, Mary, TOMBES, Mary Beth, ROBOZ, Gail, KRAMER, Lora, GRANT, Steven
Published in Clinical cancer research (01.07.2002)
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Published in Clinical cancer research (01.07.2002)
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Enforced expression of the tumor suppressor p53 renders human leukemia cells (U937) more sensitive to 1-[β- d-arabinofuranosyl]cytosine (ara-C)-induced apoptosis
Decker, Roy H., Levin, Jay, Kramer, Lora B., Dai, Yun, Grant, Steven
Published in Biochemical pharmacology (15.06.2003)
Published in Biochemical pharmacology (15.06.2003)
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Interactions between 2-Fluoroadenine 9-β-d-Arabinofuranoside and the Kinase Inhibitor UCN-01 in Human Leukemia and Lymphoma Cells
HARVEY, Sarah, DECKER, Roy, YUN DAI, SCHAEFER, Gregory, LIN TANG, KRAMER, Lora, DENT, Paul, GRANT, Steven
Published in Clinical cancer research (01.02.2001)
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Published in Clinical cancer research (01.02.2001)
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Induction of Apoptosis and Potentiation of Ceramide-mediated Cytotoxicity by Sphingoid Bases in Human Myeloid Leukemia Cells
Jarvis, W D, Fornari, F A, Traylor, R S, Martin, H A, Kramer, L B, Erukulla, R K, Bittman, R, Grant, S
Published in The Journal of biological chemistry (05.04.1996)
Published in The Journal of biological chemistry (05.04.1996)
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HDAC Inhibitors Potentiate the Activity of the BCR/ABL Kinase Inhibitor KW-2449 in Imatinib-Sensitive or -Resistant BCR/ABL+ Leukemia Cells In Vitro and In Vivo
NGUYEN, Tri, YUN DAI, ATTKISSON, Elisa, KRAMER, Lora, JORDAN, Nicholas, NGUYEN, Nguyen, KOLLURI, Nikhil, MUSCHEN, Markus, GRANT, Steven
Published in Clinical cancer research (15.05.2011)
Published in Clinical cancer research (15.05.2011)
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Modulation of Protein Kinase C Activity and Calcium-Sensitive Isoform Expression in Human Myeloid Leukemia Cells by Bryostatin 1: Relationship to Differentiation and Ara-C-Induced Apoptosis
Grant, Steven, Turner, Amy J., Freemerman, Alex J., Wang, Zhiliang, Kramer, Lora, Jarvis, W.David
Published in Experimental cell research (10.10.1996)
Published in Experimental cell research (10.10.1996)
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