Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer
Feig, Christine, Jones, James O., Kraman, Matthew, Wells, Richard J. B., Deonarine, Andrew, Chan, Derek S., Connell, Claire M., Roberts, Edward W., Qi Zhao, Caballero, Otavia L., Teichmann, Sarah A., Janowitz, Tobias, Jodrell, Duncan I., Tuveson, David A., Fearon, Douglas T.
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2013)
Get full text
Journal Article
Notch2 is required for the proliferation of cardiac neural crest‐derived smooth muscle cells
Varadkar, Prajakta, Kraman, Matthew, Despres, Daryl, Ma, Ge, Lozier, Julie, McCright, Brent
Published in Developmental dynamics (01.04.2008)
Published in Developmental dynamics (01.04.2008)
Get full text
Journal Article
CD27 mediates interleukin-2-independent clonal expansion of the CD8⁺ T cell without effector differentiation
Carr, James M, Carrasco, Marlene J, Thaventhiran, James E.D, Bambrough, Paul J, Kraman, Matthew, Edwards, Alexander D, Al-Shamkhani, Aymen, Fearon, Douglas T
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2006)
Get full text
Journal Article
BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation
LOGARAJAH, Suresh, HUNTER, Patricia, KRAMAN, Matthew, STEELE, Dawn, LAKHANI, Sunil, BOBROW, Lynda, VENKITARAMAN, Ashok, WAGNER, Simon
Published in Oncogene (28.08.2003)
Published in Oncogene (28.08.2003)
Get full text
Journal Article
A common region of 10p deleted in DiGeorge and velocardiofacial syndromes
Daw, Sara C.M, Taylor, Catherine, Kraman, Matthew, Call, Kathy, Mao, Jen-i, Schuffenhauer, Simone, Meitinger, Thomas, Lipson, Tony, Goodship, Judith, Scambler, Peter
Published in Nature genetics (01.08.1996)
Published in Nature genetics (01.08.1996)
Get full text
Journal Article
FS118, a Bispecific Antibody Targeting LAG-3 and PD-L1, Enhances T-Cell Activation Resulting in Potent Antitumor Activity
Kraman, Matthew, Faroudi, Mustapha, Allen, Natalie L, Kmiecik, Katarzyna, Gliddon, Daniel, Seal, Claire, Koers, Alexander, Wydro, Mateusz M, Batey, Sarah, Winnewisser, Julia, Young, Lesley, Tuna, Mihriban, Doody, Jacqueline, Morrow, Michelle, Brewis, Neil
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
Get full text
Journal Article
Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-α
Kraman, Matthew, Bambrough, Paul J, Arnold, James N, Roberts, Edward W, Magiera, Lukasz, Jones, James O, Gopinathan, Aarthi, Tuveson, David A, Fearon, Douglas T
Published in Science (American Association for the Advancement of Science) (05.11.2010)
Published in Science (American Association for the Advancement of Science) (05.11.2010)
Get full text
Journal Article
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
Roberts, Edward W, Deonarine, Andrew, Jones, James O, Denton, Alice E, Feig, Christine, Lyons, Scott K, Espeli, Marion, Kraman, Matthew, McKenna, Brendan, Wells, Richard J B, Zhao, Qi, Caballero, Otavia L, Larder, Rachel, Coll, Anthony P, O'Rahilly, Stephen, Brindle, Kevin M, Teichmann, Sarah A, Tuveson, David A, Fearon, Douglas T
Published in The Journal of experimental medicine (03.06.2013)
Published in The Journal of experimental medicine (03.06.2013)
Get full text
Journal Article
Pathways of memory CD8+ T‐cell development
Bannard, Oliver, Kraman, Matthew, Fearon, Douglas
Published in European journal of immunology (01.08.2009)
Published in European journal of immunology (01.08.2009)
Get full text
Journal Article
Generation of Fcabs targeting human and murine LAG-3 as building blocks for novel bispecific antibody therapeutics
Everett, Katy L., Kraman, Matthew, Wollerton, Francisca P.G., Zimarino, Carlo, Kmiecik, Katarzyna, Gaspar, Miguel, Pechouckova, Sarka, Allen, Natalie L., Doody, Jacqueline F., Tuna, Mihriban
Published in Methods (San Diego, Calif.) (01.02.2019)
Published in Methods (San Diego, Calif.) (01.02.2019)
Get full text
Journal Article
Abstract 5651: A LAG-3/PD-L1 bispecific antibody inhibits tumor growth in two syngeneic colon carcinoma models
Kraman, Matthew, Kmiecik, Katarzyna, Zimarino, Carlo, Everett, Katy, Faroudi, Mustapha, Wydro, Mateusz, Doody, Jacqueline
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Abstract 2399: LAG-3/PD-L1 mAb2 can overcome PD-L1-mediated compensatory upregulation of LAG-3 induced by single-agent checkpoint blockade
Faroudi, Mustapha, Kraman, Matthew, Fosh, Natalie, Reader, Claire, Gliddon, Daniel, Seal, Claire, Lucas, Christa, Koers, Alexander, Wydro, Mateusz, Morrow, Michelle, Brewis, Neil
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Abstract 2719: Dual blockade of PD-L1 and LAG-3 with FS118, a unique bispecific antibody, induces CD8+ T-cell activation and modulates the tumor microenvironment to promote antitumor immune responses
Kraman, Matthew, Fosh, Natalie, Kmiecik, Katarzyna, Everett, Katy, Zimarino, Carlo, Faroudi, Mustapha, Wydro, Mateusz, Koers, Alexander, Young, Lesley, Gliddon, Daniel, Morrow, Michelle, Doody, Jacqueline, Tuna, Mihriban, Brewis, Neil
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article
1353 Targeting complement factor H mediated tumor immune and complement evasion as a next generation approach
Kraman, Matthew, Zimarino, Carlo, Minns, Danielle, Dias, Jorge, Povall, Chelsea, Graves, Helen, Holub, Bradley, Minter, Ralph, Galson, Jacob, Osbourn, Jane, Finch, Donna
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
Get full text
Journal Article