Metal Drugs and the Anticancer Immune Response
Englinger, Bernhard, Pirker, Christine, Heffeter, Petra, Terenzi, Alessio, Kowol, Christian R, Keppler, Bernhard K, Berger, Walter
Published in Chemical reviews (23.01.2019)
Published in Chemical reviews (23.01.2019)
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Anticancer Thiosemicarbazones: Chemical Properties, Interaction with Iron Metabolism, and Resistance Development
Heffeter, Petra, Pape, Veronika F S, Enyedy, Éva A, Keppler, Bernhard K, Szakacs, Gergely, Kowol, Christian R
Published in Antioxidants & redox signaling (10.03.2019)
Published in Antioxidants & redox signaling (10.03.2019)
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In vitro biodistribution studies on clinically approved FGFR inhibitors ponatinib, nintedanib, erlotinib and the investigational inhibitor KP2692
Dömötör, Orsolya, Mathuber, Marlene, Kowol, Christian R.
Published in European journal of pharmaceutical sciences (01.01.2024)
Published in European journal of pharmaceutical sciences (01.01.2024)
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A Dogma in Doubt: Hydrolysis of Equatorial Ligands of Pt IV Complexes under Physiological Conditions
Kastner, Alexander, Poetsch, Isabella, Mayr, Josef, Burda, Jaroslav V, Roller, Alexander, Heffeter, Petra, Keppler, Bernhard K, Kowol, Christian R
Published in Angewandte Chemie International Edition (27.05.2019)
Published in Angewandte Chemie International Edition (27.05.2019)
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Journal Article
Copper-Catalyzed Glutathione Oxidation is Accelerated by the Anticancer Thiosemicarbazone Dp44mT and Further Boosted at Lower pH
Falcone, Enrico, Ritacca, Alessandra G., Hager, Sonja, Schueffl, Hemma, Vileno, Bertrand, El Khoury, Youssef, Hellwig, Petra, Kowol, Christian R., Heffeter, Petra, Sicilia, Emilia, Faller, Peter
Published in Journal of the American Chemical Society (17.08.2022)
Published in Journal of the American Chemical Society (17.08.2022)
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Synthesis and Cytotoxicity of Water-Soluble Dual- and Triple-Action Satraplatin Derivatives: Replacement of Equatorial Chlorides of Satraplatin by Acetates
Karmakar, Subhendu, Poetsch, Isabella, Kowol, Christian R, Heffeter, Petra, Gibson, Dan
Published in Inorganic chemistry (16.12.2019)
Published in Inorganic chemistry (16.12.2019)
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Structure-Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands
Fronik, Philipp, Poetsch, Isabella, Kastner, Alexander, Mendrina, Theresa, Hager, Sonja, Hohenwallner, Katharina, Schueffl, Hemma, Herndler-Brandstetter, Dietmar, Koellensperger, Gunda, Rampler, Evelyn, Kopecka, Joanna, Riganti, Chiara, Berger, Walter, Keppler, Bernhard K, Heffeter, Petra, Kowol, Christian R
Published in Journal of medicinal chemistry (26.08.2021)
Published in Journal of medicinal chemistry (26.08.2021)
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An albumin-based tumor-targeted oxaliplatin prodrug with distinctly improved anticancer activity in vivo
Mayr, Josef, Heffeter, Petra, Groza, Diana, Galvez, Luis, Koellensperger, Gunda, Roller, Alexander, Alte, Beatrix, Haider, Melanie, Berger, Walter, Kowol, Christian R, Keppler, Bernhard K
Published in Chemical science (Cambridge) (01.03.2017)
Published in Chemical science (Cambridge) (01.03.2017)
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Elemental analysis: an important purity control but prone to manipulations
Kandioller, Wolfgang, Theiner, Johannes, Keppler, Bernhard K, Kowol, Christian R
Published in Inorganic chemistry frontiers (01.02.2022)
Published in Inorganic chemistry frontiers (01.02.2022)
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Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI‑2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux
Bormio Nunes, Julia H, Hager, Sonja, Mathuber, Marlene, Pósa, Vivien, Roller, Alexander, Enyedy, Éva A, Stefanelli, Alessia, Berger, Walter, Keppler, Bernhard K, Heffeter, Petra, Kowol, Christian R
Published in Journal of medicinal chemistry (25.11.2020)
Published in Journal of medicinal chemistry (25.11.2020)
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Journal Article
Multi-action platinum(IV) prodrugs conjugated with COX-inhibiting NSAIDs
Liu, Xiao, Wenisch, Dominik, Dahlke, Philipp, Jordan, Paul M., Jakupec, Michael A., Kowol, Christian R., Liebing, Phil, Werz, Oliver, Keppler, Bernhard K., Weigand, Wolfgang
Published in European journal of medicinal chemistry (05.09.2023)
Published in European journal of medicinal chemistry (05.09.2023)
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Degradable Bottlebrush Polypeptides and the Impact of their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo
Strasser, Paul, Montsch, Bianca, Weiss, Silvia, Sami, Haider, Kugler, Christoph, Hager, Sonja, Schueffl, Hemma, Mader, Robert, Brüggemann, Oliver, Kowol, Christian R., Ogris, Manfred, Heffeter, Petra, Teasdale, Ian
Published in Small (Weinheim an der Bergstrasse, Germany) (01.06.2023)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.06.2023)
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Another step toward DNA selective targeting: Ni(II) and Cu(II) complexes of a Schiff base ligand able to bind gene promoter G-quadruplexes
Terenzi, Alessio, Lötsch, Daniela, van Schoonhoven, Sushilla, Roller, Alexander, Kowol, Christian R, Berger, Walter, Keppler, Bernhard K, Barone, Giampaolo
Published in Dalton transactions : an international journal of inorganic chemistry (04.05.2016)
Published in Dalton transactions : an international journal of inorganic chemistry (04.05.2016)
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Albumin-targeting of an oxaliplatin-releasing platinum( iv ) prodrug results in pronounced anticancer activity due to endocytotic drug uptake in vivo
Schueffl, Hemma, Theiner, Sarah, Hermann, Gerrit, Mayr, Josef, Fronik, Philipp, Groza, Diana, van Schonhooven, Sushilla, Galvez, Luis, Sommerfeld, Nadine S., Schintlmeister, Arno, Reipert, Siegfried, Wagner, Michael, Mader, Robert M., Koellensperger, Gunda, Keppler, Bernhard K., Berger, Walter, Kowol, Christian R., Legin, Anton, Heffeter, Petra
Published in Chemical science (Cambridge) (06.10.2021)
Published in Chemical science (Cambridge) (06.10.2021)
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The coordination modes of (thio)semicarbazone copper(II) complexes strongly modulate the solution chemical properties and mechanism of anticancer activity
Pósa, Vivien, Hajdu, Bálint, Tóth, Gábor, Dömötör, Orsolya, Kowol, Christian R., Keppler, Bernhard K., Spengler, Gabriella, Gyurcsik, Béla, Enyedy, Éva A.
Published in Journal of inorganic biochemistry (01.06.2022)
Published in Journal of inorganic biochemistry (01.06.2022)
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