Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system
Chanda, Pranab K, Gao, Ying, Mark, Lilly, Btesh, Joan, Strassle, Brian W, Lu, Peimin, Piesla, Michael J, Zhang, Mei-Yi, Bingham, Brendan, Uveges, Albert, Kowal, Dianne, Garbe, David, Kouranova, Evguenia V, Ring, Robert H, Bates, Brian, Pangalos, Menelas N, Kennedy, Jeffrey D, Whiteside, Garth T, Samad, Tarek A
Published in Molecular pharmacology (01.12.2010)
Published in Molecular pharmacology (01.12.2010)
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The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise?
Sukoff Rizzo, Stacey J, Leonard, Sarah K, Gilbert, Adam, Dollings, Paul, Smith, Deborah L, Zhang, Mei-Yi, Di, Li, Platt, Brian J, Neal, Sarah, Dwyer, Jason M, Bender, Corey N, Zhang, Jean, Lock, Tim, Kowal, Dianne, Kramer, Angela, Randall, Andrew, Huselton, Christine, Vishwanathan, Karthick, Tse, Susanna Y, Butera, John, Ring, Robert H, Rosenzweig-Lipson, Sharon, Hughes, Zoë A, Dunlop, John
Published in The Journal of pharmacology and experimental therapeutics (01.07.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2011)
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5-Piperazinyl-3-sulfonylindazoles as Potent and Selective 5-Hydroxytryptamine-6 Antagonists
Liu, Kevin G, Robichaud, Albert J, Bernotas, Ronald C, Yan, Yinfa, Lo, Jennifer R, Zhang, Mei-Yi, Hughes, Zoe A, Huselton, Christine, Zhang, Guo Ming, Zhang, Jean Y, Kowal, Dianne M, Smith, Deborah L, Schechter, Lee E, Comery, Thomas A
Published in Journal of medicinal chemistry (11.11.2010)
Published in Journal of medicinal chemistry (11.11.2010)
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Pharmacological comparison of muscarinic ligands : Historical versus more recent muscarinic M1-preferring receptor agonists
HEINRICH, Julia N, BUTERA, John A, TSENG, Eugene, UVEGES, Albert J, MAYER, Scott C, CARRICK, Tikva, KRAMER, Angela, KOWAL, Dianne, LOCK, Tim, MARQUIS, Karen L, PAUSCH, Mark H, POPIOLEK, Mike, SUN, Shaiu-Ching
Published in European journal of pharmacology (01.03.2009)
Published in European journal of pharmacology (01.03.2009)
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Identification of a series of benzoxazoles as potent 5-HT6 ligands
Liu, Kevin G, Lo, Jennifer R, Comery, Thomas A, Zhang, Guo Ming, Zhang, Jean Y, Kowal, Dianne M, Smith, Deborah L, Di, Li, Kerns, Edward H, Schechter, Lee E, Robichaud, Albert J
Published in Bioorganic & medicinal chemistry letters (15.02.2009)
Published in Bioorganic & medicinal chemistry letters (15.02.2009)
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Potent dihydroquinolinone dopamine D2 partial agonist/serotonin reuptake inhibitors for the treatment of schizophrenia
YINFA YAN, PING ZHOU, CARRICK, Tikva, MARQUIS, Karen L, PAUSCH, Mark H, ROBICHAUD, Albert J, ROTELLA, David P, FEENSTRA, Rolf, KRUSE, Chris G, REINDERS, Jan-Hendrik, VAN DER NEUT, Martina, LAI, Margaret, ZHANG, Jean, KOWAL, Dianne M
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT6 antagonists
Liu, Kevin G., Robichaud, Albert J., Greenfield, Alexander A., Lo, Jennifer R., Grosanu, Cristina, Mattes, James F., Cai, Yanxuan, Zhang, Guo Ming, Zhang, Jean Y., Kowal, Dianne M., Smith, Deborah L., Di, Li, Kerns, Edward H., Schechter, Lee E., Comery, Thomas A.
Published in Bioorganic & medicinal chemistry (01.01.2011)
Published in Bioorganic & medicinal chemistry (01.01.2011)
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The Role of Transmembrane Helix 5 in Agonist Binding to the Human H3 Receptor
Uveges, Albert J, Kowal, Dianne, Zhang, Yingxin, Spangler, Taylor B, Dunlop, John, Semus, Simon, Jones, Philip G
Published in The Journal of pharmacology and experimental therapeutics (01.05.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2002)
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1-Sulfonylindazoles as potent and selective 5-HT6 ligands
LIU, Kevin G, LO, Jennifer R, ROBICHAUD, Albert J, COMERY, Thomas A, GUO MING ZHANG, ZHANG, Jean Y, KOWAL, Dianne M, SMITH, Deborah L, LI DI, KERNS, Edward H, SCHECHTER, Lee E
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective α2A-adrenoceptor antagonism
Dwyer, Jason M., Platt, Brian J., Sukoff Rizzo, Stacey J., Pulicicchio, Claudine M., Wantuch, Caitlin, Zhang, Mei-Yi, Cummons, Terri, Leventhal, Liza, Bender, Corey N., Zhang, Jean, Kowal, Dianne, Lu, Shendi, Rajarao, S. Johannes R., Smith, Deborah L., Shilling, Adam D., Wang, Jianyao, Butera, John, Resnick, Lynn, Rosenzweig-Lipson, Sharon, Schechter, Lee E., Beyer, Chad E.
Published in The international journal of neuropsychopharmacology (01.10.2010)
Published in The international journal of neuropsychopharmacology (01.10.2010)
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Characterization of Novel Aryl-Ether, Biaryl, and Fluorene Aspartic Acid and Diaminopropionic Acid Analogs as Potent Inhibitors of the High-Affinity Glutamate Transporter EAAT2
Dunlop, John, McIlvain, H Beal, Carrick, Tikva A, Jow, Brian, Lu, Qiang, Kowal, Dianne, Lin, Steven, Greenfield, Alexander, Grosanu, Cristina, Fan, Kristi, Petroski, Robert, Williams, John, Foster, Alan, Butera, John
Published in Molecular pharmacology (01.10.2005)
Published in Molecular pharmacology (01.10.2005)
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A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands
LIU, Kevin G, LO, Jennifer R, ROBICHAUD, Albert J, COMERY, Thomas A, GUO MING ZHANG, ZHANG, Jean Y, KOWAL, Dianne M, SMITH, Deborah L, LI DI, KERNS, Edward H, SCHECHTER, Lee E
Published in Bioorganic & medicinal chemistry letters (15.07.2008)
Published in Bioorganic & medicinal chemistry letters (15.07.2008)
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Tetrahydrocarbazole-based serotonin reuptake inhibitor/dopamine D2 partial agonists for the potential treatment of schizophrenia
ROTELLA, David P, MCFARLANE, Geraldine R, MCCREARY, Andrew, KRUSE, Chris G, SULLIVAN, Kelly, PRUTHI, Farhana, LAI, Margaret, ZHANG, Jean, KOWAL, Dianne M, CARRICK, Tikva, GRAUER, Steven M, NAVARRA, Rachel L, GREENFIELD, Alexander, GRAF, Radka, BRENNAN, Julie, MARQUIS, Karen L, PAUSCH, Mark H, GROSANU, Cristina, ROBICHAUD, Albert J, DENNY, Rajiah Aldrin, FEENSTRA, Rolf W, NUNEZ-GARCIA, Sara, REINDERS, Jan-Hendrik, VAN DER NEUT, Martina
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Identification of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT6 ligands
LIU, Kevin G, LO, Jennifer R, ROBICHAUD, Albert J, COMERY, Thomas A, GUO MING ZHANG, ZHANG, Jean Y, KOWAL, Dianne M, SMITH, Deborah L, LI DI, KERNS, Edward H, SCHECHTER, Lee E
Published in Bioorganic & medicinal chemistry letters (15.06.2009)
Published in Bioorganic & medicinal chemistry letters (15.06.2009)
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WAY‐855 (3‐amino‐tricyclo[2.2.1.02.6]heptane‐1,3‐dicarboxylic acid): a novel, EAAT2‐preferring, nonsubstrate inhibitor of high‐affinity glutamate uptake
Dunlop, John, Eliasof, Scott, Stack, Gary, McIlvain, H Beal, Greenfield, Alexander, Kowal, Dianne, Petroski, Robert, Carrick, Tikva
Published in British journal of pharmacology (01.11.2003)
Published in British journal of pharmacology (01.11.2003)
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Synthesis and biological activities of aryl-ether-, biaryl-, and fluorene-aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT-2
Greenfield, Alexander, Grosanu, Cristina, Dunlop, John, McIlvain, Beal, Carrick, Tikva, Jow, Brian, Lu, Qiang, Kowal, Dianne, Williams, John, Butera, John
Published in Bioorganic & medicinal chemistry letters (15.11.2005)
Published in Bioorganic & medicinal chemistry letters (15.11.2005)
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Characterization of Two Novel N-Methyl-D-aspartate Antagonists: EAA-090 (2-[8,9-Dioxo-2,6-diazabicyclo [5.2.0]non-1(7)-en2-yl]ethylphosphonic Acid) and EAB-318 (R-α-Amino-5-chloro-1-(phosphonomethyl)-1H-benzimidazole-2-propanoic Acid Hydrochloride)
Sun, Lucy, Chiu, Doreen, Kowal, Dianne, Simon, Rachelle, Smeyne, Michelle, Zukin, R Suzanne, Olney, John, Baudy, Reinhardt, Lin, Stephen
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
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Identification of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT 6 ligands
Liu, Kevin G., Lo, Jennifer R., Comery, Thomas A., Zhang, Guo Ming, Zhang, Jean Y., Kowal, Dianne M., Smith, Deborah L., Di, Li, Kerns, Edward H., Schechter, Lee E., Robichaud, Albert J.
Published in Bioorganic & medicinal chemistry letters (15.06.2009)
Published in Bioorganic & medicinal chemistry letters (15.06.2009)
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Design, Synthesis, SAR, and Biological Evaluation of Highly Potent Benzimidazole-Spaced Phosphono-α-Amino Acid Competitive NMDA Antagonists of the AP-6 Type
Baudy, Reinhardt B, Yardley, John P, Zaleska, Margaret M, Bramlett, Donna R, Tasse, Rene P, Kowal, Dianne M, Katz, Alan H, Moyer, John A, Abou-Gharbia, Magid
Published in Journal of medicinal chemistry (10.05.2001)
Published in Journal of medicinal chemistry (10.05.2001)
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