Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2
Arenas-Ramirez, Natalia, Zou, Chao, Popp, Simone, Zingg, Daniel, Brannetti, Barbara, Wirth, Emmanuelle, Calzascia, Thomas, Kovarik, Jiri, Sommer, Lukas, Zenke, Gerhard, Woytschak, Janine, Regnier, Catherine H, Katopodis, Andreas, Boyman, Onur
Published in Science translational medicine (30.11.2016)
Published in Science translational medicine (30.11.2016)
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The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation
Evenou, Jean-Pierre, Wagner, Jürgen, Zenke, Gerhard, Brinkmann, Volker, Wagner, Kathrin, Kovarik, Jiri, Welzenbach, Karl A, Weitz-Schmidt, Gabriele, Guntermann, Christine, Towbin, Harry, Cottens, Sylvain, Kaminski, Sandra, Letschka, Thomas, Lutz-Nicoladoni, Christina, Gruber, Thomas, Hermann-Kleiter, Natascha, Thuille, Nikolaus, Baier, Gottfried
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
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Orally Bioavailable Isothioureas Block Function of the Chemokine Receptor CXCR4 In Vitro and In Vivo
Thoma, Gebhard, Streiff, Markus B, Kovarik, Jiri, Glickman, Fraser, Wagner, Trixie, Beerli, Christian, Zerwes, Hans-Günter
Published in Journal of medicinal chemistry (25.12.2008)
Published in Journal of medicinal chemistry (25.12.2008)
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Targeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via programmed death ligand 1
Fiorina, Paolo, Jurewicz, Mollie, Vergani, Andrea, Petrelli, Alessandra, Carvello, Michele, D'Addio, Francesca, Godwin, Jonathan G, Law, Kenneth, Wu, Erxi, Tian, Ze, Thoma, Gebhard, Kovarik, Jiri, La Rosa, Stefano, Capella, Carlo, Rodig, Scott, Zerwes, Hans-Guenter, Sayegh, Mohamed H, Abdi, Reza
Published in The Journal of immunology (1950) (01.01.2011)
Published in The Journal of immunology (1950) (01.01.2011)
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Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A
Fischman, Sharon, Levin, Itay, Rondeau, Jean-Michel, Štrajbl, Marek, Lehmann, Sylvie, Huber, Thomas, Nimrod, Guy, Cebe, Régis, Omer, Dotan, Kovarik, Jiri, Bernstein, Shmuel, Sasson, Yehezkel, Demishtein, Alik, Shlamkovich, Tomer, Bluvshtein, Olga, Grossman, Noam, Barak-Fuchs, Reut, Zhenin, Michael, Fastman, Yair, Twito, Shir, Vana, Tal, Zur, Nevet, Ofran, Yanay
Published in Communications biology (29.09.2023)
Published in Communications biology (29.09.2023)
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CpG Oligodeoxynucleotides Can Circumvent the Th2 Polarization of Neonatal Responses to Vaccines But May Fail to Fully Redirect Th2 Responses Established by Neonatal Priming
Kovarik, Jiri, Bozzotti, Paola, Love-Homan, Laurie, Pihlgren, Maria, Davis, Heather L, Lambert, Paul-Henri, Krieg, Arthur M, Siegrist, Claire-Anne
Published in The Journal of immunology (1950) (01.02.1999)
Published in The Journal of immunology (1950) (01.02.1999)
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Determinants of infant responses to vaccines in presence of maternal antibodies
Siegrist, Claire-Anne, Córdova, Marco, Brandt, Christian, Barrios, Christy, Berney, Monika, Tougne, Chantal, Kovarik, Jiri, Lambert, Paul-Henri
Published in Vaccine (01.08.1998)
Published in Vaccine (01.08.1998)
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Conference Proceeding
Neutralization of IL-1β and P-Selectin Inhibition Attenuate Organ Injury in Mice with Sickle Cell Disease
Gotardo, Erica M.F., Gushiken, Lucas F.S., Brito, Pamela L, Leonardo, Flavia C., Torres, Lidiane S., Agoulnik, Sergei, Kovarik, Jiri, Bruederle, Andreas, Millholland, John, Costa, Fernando Ferreira, Conran, Nicola
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Neutralization of Inflammasome-Processed Cytokines Reduces Inflammatory Mechanisms and Leukocyte Recruitment in the Vasculature of TNF-α-Stimulated Sickle Cell Disease Mice
Torres, Lidiane S., Gotardo, Erica M.F., Leonardo, Flávia Costa, Brito, Pamela L., Förster, Irmgard, Kovarik, Jiri, Costa, Fernando Ferreira, Conran, Nicola
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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P-Selectin Blockage Potentiates the Inhibiting Effects of Inflammasome Cytokine Neutralization on Leukocyte Recruitment in an In Vivo Model of Acute Sickle Cell Vaso-Occlusion
Gotardo, Erica M.F., Torres, Lidiane S., Gushiken, Lucas F.S., Brito, Pamela L., Leonardo, Flavia C., Agoulnik, Sergei, Kovarik, Jiri, Bruederle, Andreas, Millholland, John, Vitaliti, Alessandra, Förster, Irmgard, Costa, Fernando Ferreira, Conran, Nicola
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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아토피성 피부염 또는 관련 병태의 치료 및/또는 예방을 위한 IL-18 길항제의 용도
LOESCHE CHRISTIAN, FERRERO ENRICO, JUNT TOBIAS, KOLBINGER FRANK, KOVARIK JIRI
Year of Publication 26.06.2023
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Year of Publication 26.06.2023
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The T‐cell fingerprint of MALT1 paracaspase revealed by selective inhibition
Bardet, Maureen, Unterreiner, Adeline, Malinverni, Claire, Lafossas, Frédérique, Vedrine, Corinne, Boesch, Danielle, Kolb, Yeter, Kaiser, Daniel, Glück, Anton, Schneider, Martin A, Katopodis, Andreas, Renatus, Martin, Simic, Oliver, Schlapbach, Achim, Quancard, Jean, Régnier, Catherine H, Bold, Guido, Pissot‐Soldermann, Carole, Carballido, José M, Kovarik, Jiri, Calzascia, Thomas, Bornancin, Frédéric
Published in Immunology and cell biology (01.01.2018)
Published in Immunology and cell biology (01.01.2018)
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Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD
Hechinger, Anne-Kathrin, Smith, BenjaminA.H., Flynn, Ryan, Hanke, Kathrin, McDonald-Hyman, Cameron, Taylor, Patricia A., Pfeifer, Dietmar, Hackanson, Björn, Leonhardt, Franziska, Prinz, Gabriele, Dierbach, Heide, Schmitt-Graeff, Annette, Kovarik, Jiri, Blazar, Bruce R., Zeiser, Robert
Published in Blood (15.01.2015)
Published in Blood (15.01.2015)
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NLRC4-GOF 염증복합체병증의 치료에 사용하기 위한 이중특이적 항체
JUNGE GUIDO, STEIN RICHARD, WALDRON LYNCH FRANK, KIFFE MICHAEL, KOVARIK JIRI
Year of Publication 21.07.2023
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Year of Publication 21.07.2023
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Requirement of Mucosa‐Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor–Induced Arthritis, but Not Fcγ Receptor–Mediated Platelet Elimination, in Mice
Martin, Kea, Touil, Ratiba, Cvijetic, Grozdan, Israel, Laura, Kolb, Yeter, Sarret, Sophie, Valeaux, Stéphanie, Degl'Innocenti, Elena, Le Meur, Thomas, Caesar, Nadja, Bardet, Maureen, Beerli, Christian, Zerwes, Hans‐Guenter, Kovarik, Jiri, Beltz, Karen, Schlapbach, Achim, Quancard, Jean, Régnier, Catherine H., Bigaud, Marc, Junt, Tobias, Wieczorek, Grazyna, Isnardi, Isabelle, Littlewood‐Evans, Amanda, Bornancin, Frédéric, Calzascia, Thomas
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2020)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2020)
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DPP9 enzymatic activity in hematopoietic cells is dispensable for mouse hematopoiesis
Kim, Munkyung, von Muenchow, Lilly, Le Meur, Thomas, Kueng, Benjamin, Gapp, Berangere, Weber, Delphine, Dietrich, William, Kovarik, Jiri, Rolink, Antonius G., Ksiazek, Iwona
Published in Immunology letters (01.06.2018)
Published in Immunology letters (01.06.2018)
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Common Gamma Chain Cytokines Contribute To Acute GvHD Via Perforin/Granzyme B-Mediated Cytotoxicity Of CD8 T Cells
Schwarze, Vincent, Hechinger, Anne-Kathrin, Leonhardt, Franziska, Prinz, Gabriele, Schmitt-Gräff, Annette, Kovarik, Jiri, Zeiser, Robert
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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METHOD OF MANUFACTURING BISPECIFIC ANTIBODIES BISPECIFIC ANTIBODIES AND THERAPEUTIC USE OF SUCH ANTIBODIES
BUCH TINA, WOISETSCHLAEGER MAXIMILIAN, PATEL DHAVALKUMAR, KOEHLER ROLF, GRAF CHRISTIAN, HEITMANN DANIEL, BARDROFF MICHAEL OTTO, JOSTOCK THOMAS, KOVARIK JIRI, KNOPF HANS PETER, OLIVER STEPHEN JOHN
Year of Publication 20.12.2022
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Year of Publication 20.12.2022
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Thin-film SnO2 and ZnO detectors of hydrogen peroxide vapors
Aroutiounian, Vladimir, Arakelyan, Valeri, Aleksanyan, Mikayel, Shahnazaryan, Gohar, Kacer, Petr, Picha, Pavel, Kovarik, Jiri, Pekarek, Jakub, Berndt Joost
Published in Journal of sensors and sensor systems (16.04.2018)
Published in Journal of sensors and sensor systems (16.04.2018)
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