Open Systems Pharmacology Community—An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences
Lippert, Jörg, Burghaus, Rolf, Edginton, Andrea, Frechen, Sebastian, Karlsson, Mats, Kovar, Andreas, Lehr, Thorsten, Milligan, Peter, Nock, Valerie, Ramusovic, Sergej, Riggs, Matthew, Schaller, Stephan, Schlender, Jan, Schmidt, Stephan, Sevestre, Michaël, Sjögren, Erik, Solodenko, Juri, Staab, Alexander, Teutonico, Donato
Published in CPT: pharmacometrics and systems pharmacology (01.12.2019)
Published in CPT: pharmacometrics and systems pharmacology (01.12.2019)
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Journal Article
The clinical pharmacokinetics of phosphodiesterase-5 inhibitors for erectile dysfunction
Gupta, Manish, Kovar, Andreas, Meibohm, Bernd
Published in Journal of clinical pharmacology (01.09.2005)
Published in Journal of clinical pharmacology (01.09.2005)
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Journal Article
Phase I Study of the Humanized Antiepidermal Growth Factor Receptor Monoclonal Antibody EMD72000 in Patients With Advanced Solid Tumors That Express the Epidermal Growth Factor Receptor
VANHOEFER, Udo, TEWES, Mitra, SEEBER, Siegfried, HARSTRICK, Andreas, BASELGA, José, ROJO, Federico, DIRSCH, Olaf, SCHLEUCHER, Norbert, ROSEN, Oliver, TILLNER, Joachim, KOVAR, Andreas, BRAUN, Ada H, TRARBACH, Tanja
Published in Journal of clinical oncology (01.01.2004)
Published in Journal of clinical oncology (01.01.2004)
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Journal Article
A randomized multi-center phase II trial of the angiogenesis inhibitor Cilengitide (EMD 121974) and gemcitabine compared with gemcitabine alone in advanced unresectable pancreatic cancer
Friess, Helmut, Langrehr, Jan M, Oettle, Helmut, Raedle, Jochen, Niedergethmann, Marco, Dittrich, Christian, Hossfeld, Dieter K, Stöger, Herbert, Neyns, Bart, Herzog, Peter, Piedbois, Pascal, Dobrowolski, Frank, Scheithauer, Werner, Hawkins, Robert, Katz, Frieder, Balcke, Peter, Vermorken, Jan, van Belle, Simon, Davidson, Neville, Esteve, Albert Abad, Castellano, Daniel, Kleeff, Jörg, Tempia-Caliera, Adrien A, Kovar, Andreas, Nippgen, Johannes
Published in BMC cancer (11.12.2006)
Published in BMC cancer (11.12.2006)
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Journal Article
Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma
Ribas, Antoni, Kirkwood, John M, Atkins, Michael B, Whiteside, Theresa L, Gooding, William, Kovar, Andreas, Gillies, Stephen D, Kashala, Oscar, Morse, Michael A
Published in Journal of translational medicine (29.07.2009)
Published in Journal of translational medicine (29.07.2009)
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Journal Article
Investigation of sarizotan's impact on the pharmacokinetics of probe drugs for major cytochrome P450 isoenzymes : A combined cocktail trial
KRÖSSER, Sonja, NEUGEBAUER, Roland, DOLGOS, Hugues, FLUCK, Markus, ROST, Karl-Ludwig, KOVAR, Andreas
Published in European journal of clinical pharmacology (01.04.2006)
Published in European journal of clinical pharmacology (01.04.2006)
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Journal Article
Sutimlimab Pharmacokinetics and Pharmacodynamics in Patients with Cold Agglutinin Disease
Frank, Thomas, Kovar, Andreas, Strougo, Ashley, Vage, Chandravathi, Teuscher, Nathan, Wong, Nancy
Published in The Journal of pharmacology and experimental therapeutics (01.08.2023)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2023)
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Journal Article
Metabolism and disposition of the αv-integrin ß3/ß5 receptor antagonist cilengitide, a cyclic polypeptide, in humans
Becker, Andreas, von Richter, Oliver, Kovar, Andreas, Scheible, Holger, van Lier, Jan J, Johne, Andreas
Published in Journal of clinical pharmacology (01.07.2015)
Published in Journal of clinical pharmacology (01.07.2015)
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Journal Article
Safety, tolerability, and pharmacokinetics of the novel αv-integrin antibody EMD 525797 (DI17E6) in healthy subjects after ascending single intravenous doses
Uhl, Wolfgang, Zühlsdorf, Michael, Koernicke, Thomas, Forssmann, Ulf, Kovar, Andreas
Published in Investigational new drugs (01.04.2014)
Published in Investigational new drugs (01.04.2014)
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Journal Article
Safety, tolerability, and pharmacokinetics of the novel [alpha]v-integrin antibody EMD 525797 (DI17E6) in healthy subjects after ascending single intravenous doses
Uhl, Wolfgang, Zühlsdorf, Michael, Koernicke, Thomas, ssmann, Ulf, Kovar, Andreas
Published in Investigational new drugs (01.04.2014)
Published in Investigational new drugs (01.04.2014)
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Journal Article
Abstract 1296: Safety, tolerability, and pharmacokinetics of the novel αv-integrin antibody DI17E6 in healthy subjects after ascending single intravenous doses
Zühlsdorf, Michael, Kovar, Andreas, Uhl, Wolfgang, Forssmann, Ulf
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
Population pharmacokinetics of cilengitide in adult and pediatric cancer patients from a nonlinear mixed-effects analysis
Zühlsdorf, Michael, Bhattaram, Venkatesh Atul, Campioni, Marco, Krösser, Sonja, Derendorf, Hartmut, Kovar, Andreas
Published in Journal of clinical pharmacology (01.12.2014)
Published in Journal of clinical pharmacology (01.12.2014)
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Journal Article
Refinement of the Population Pharmacokinetic Model for the Monoclonal Antibody Matuzumab: External Model Evaluation and Simulations
Kuester, Katharina, Kovar, Andreas, Lüpfert, Christian, Brockhaus, Brigitte, Kloft, Charlotte
Published in Clinical pharmacokinetics (01.01.2009)
Published in Clinical pharmacokinetics (01.01.2009)
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Journal Article
Abstract B214: Use of a pharmacokinetic model derived from early clinical studies to assess the relevance of covariates on cilengitide pharmacokinetics
Zuehlsdorf, Michael, Bhattaram, Venkatesh Atul, Kroesser, Sonja, Derendorf, Hartmut, Kovar, Andreas
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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Journal Article
Pharmacokinetic profile of cetuximab (Erbitux™) alone and in combination with irinotecan in patients with advanced EGFR-positive adenocarcinoma
Delbaldo, Catherine, Pierga, Jean-Yves, Dieras, Véronique, Faivre, Sandrine, Laurence, Valérie, Vedovato, Jean-Claude, Bonnay, Marc, Mueser, Matthias, Nolting, Arno, Kovar, Andreas, Raymond, Eric
Published in European journal of cancer (1990) (01.08.2005)
Published in European journal of cancer (1990) (01.08.2005)
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