A caged E3 ligase ligand for PROTAC-mediated protein degradation with light
Kounde, Cyrille S, Shchepinova, Maria M, Saunders, Charlie N, Muelbaier, Marcel, Rackham, Mark D, Harling, John D, Tate, Edward W
Published in Chemical communications (Cambridge, England) (21.05.2020)
Published in Chemical communications (Cambridge, England) (21.05.2020)
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Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)
Zhang, Qisi, Kounde, Cyrille S, Mondal, Milon, Greenfield, Jake L, Baker, Jennifer R, Kotelnikov, Sergei, Ignatov, Mikhail, Tinworth, Christopher P, Zhang, Leran, Conole, Daniel, De Vita, Elena, Kozakov, Dima, McCluskey, Adam, Harling, John D, Fuchter, Matthew J, Tate, Edward W
Published in Chemical communications (Cambridge, England) (29.09.2022)
Published in Chemical communications (Cambridge, England) (29.09.2022)
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NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models
Moquin, Stephanie A, Simon, Oliver, Karuna, Ratna, Lakshminarayana, Suresh B, Yokokawa, Fumiaki, Wang, Feng, Saravanan, Chandra, Zhang, Jin, Day, Craig W, Chan, Katherine, Wang, Qing-Yin, Lu, Siyan, Dong, Hongping, Wan, Kah Fei, Lim, Siew Pheng, Liu, Wei, Seh, Cheah Chen, Chen, Yen-Liang, Xu, Haoying, Barkan, David T, Kounde, Cyrille S, Sim, Wei Lin Sandra, Wang, Gang, Yeo, Hui-Quan, Zou, Bin, Chan, Wai Ling, Ding, Mei, Song, Jae-Geun, Li, Min, Osborne, Colin, Blasco, Francesca, Sarko, Christopher, Beer, David, Bonamy, Ghislain M C, Sasseville, Vito G, Shi, Pei-Yong, Diagana, Thierry T, Yeung, Bryan K S, Gu, Feng
Published in Science translational medicine (03.02.2021)
Published in Science translational medicine (03.02.2021)
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Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit
Kounde, Cyrille S., Yeo, Hui-Quan, Wang, Qing-Yin, Wan, Kah Fei, Dong, Hongping, Karuna, Ratna, Dix, Ina, Wagner, Trixie, Zou, Bin, Simon, Oliver, Bonamy, Ghislain M.C., Yeung, Bryan K.S., Yokokawa, Fumiaki
Published in Bioorganic & medicinal chemistry letters (15.03.2017)
Published in Bioorganic & medicinal chemistry letters (15.03.2017)
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Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Antitubercular Agents
Yokokawa, Fumiaki, Wang, Gang, Chan, Wai Ling, Ang, Shi Hua, Wong, Josephine, Ma, Ida, Rao, Srinivasa P S, Manjunatha, Ujjini, Lakshminarayana, Suresh B, Herve, Maxime, Kounde, Cyrille, Tan, Bee Huat, Thayalan, Pamela, Ng, Seow Hwee, Nanjundappa, Mahesh, Ravindran, Sindhu, Gee, Peck, Tan, Maria, Wei, Liu, Goh, Anne, Chen, Pei-Yu, Lee, Kok Sin, Zhong, Chen, Wagner, Trixie, Dix, Ina, Chatterjee, Arnab K, Pethe, Kevin, Kuhen, Kelli, Glynne, Richard, Smith, Paul, Bifani, Pablo, Jiricek, Jan
Published in ACS medicinal chemistry letters (09.05.2013)
Published in ACS medicinal chemistry letters (09.05.2013)
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N-치환된 테트라히드로티에노피리딘 유도체 및 이의 용도
YEUNG BRYAN KS, YOKOKAWA FUMIAKI, WANG GANG, SIMON OLIVER, YEO HUI QUAN, KOUNDE CYRILLE, ZOU BIN, SIM WEI LIN SANDRA
Year of Publication 03.03.2021
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Year of Publication 03.03.2021
Patent
Corrrection to Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Novel Antitubercular Agents
Yokokawa, Fumiaki, Wang, Gang, Chan, Wai Ling, Ang, Shi Hua, Wong, Josephine, Ma, Ida, Rao, Srinivasa P S, Manjunatha, Ujjini, Lakshminarayana, Suresh B, Herve, Maxime, Kounde, Cyrille, Tan, Bee Huat, Thayalan, Pamela, Dick, Thomas, Ng, Seow Hwee, Nanjundappa, Mahesh, Ravindran, Sindhu, Gee, Peck, Tan, Maria, Wei, Liu, Goh, Anne, Chen, Pei-Yu, Lee, Kok Sin, Zhang, Chen, Wagner, Trixie, Dix, Ina, Chatterjee, Arnab, Pethe, Kevin, Kuhen, Kelli, Glynne, Richard, Smith, Paul, Bifani, Pablo, Jiricek, Jan
Published in ACS medicinal chemistry letters (10.04.2014)
Published in ACS medicinal chemistry letters (10.04.2014)
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N-substituted tetrahydrothienopyridine derivatives and uses thereof
Yeo, Hui Quan, Yeung, Bryan K S, Wang, Gang, Yokokawa, Fumiaki, Zou, Bin, Kounde, Cyrille, Sim, Wei Lin Sandra, Simon, Oliver
Year of Publication 18.06.2024
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Year of Publication 18.06.2024
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PROCESS TO MAKE N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 14.06.2023
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Year of Publication 14.06.2023
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PROCESS TO MAKE N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 26.04.2023
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Year of Publication 26.04.2023
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N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 11.01.2023
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Year of Publication 11.01.2023
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N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan Ks, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 07.06.2021
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Year of Publication 07.06.2021
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N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF
Yeo, Hui Quan, Wang, Gang, Yeung, Bryan KS, Yokokawa, Fumiaki, Zou, Bin, Kounde, Cyrille, Sim, Wei Lin Sandra, Simon, Oliver
Year of Publication 10.03.2022
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Year of Publication 10.03.2022
Patent
N-substituted tetrahydrothienopyridine derivatives and uses thereof
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 24.02.2022
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Year of Publication 24.02.2022
Patent
N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF
SIM, Wei Lin Sandra, ZOU, Bin, KOUNDE, Cyrille, YEUNG, Bryan KS, WANG, Gang, YEO, Hui Quan, YOKOKAWA, Fumiaki, SIMON, Oliver
Year of Publication 28.04.2021
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Year of Publication 28.04.2021
Patent