The challenge of new drug discovery for tuberculosis
Koul, Anil, Arnoult, Eric, Lounis, Nacer, Guillemont, Jerome, Andries, Koen
Published in Nature (London) (27.01.2011)
Published in Nature (London) (27.01.2011)
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Journal Article
Acquired resistance of Mycobacterium tuberculosis to bedaquiline
Andries, Koen, Villellas, Cristina, Coeck, Nele, Thys, Kim, Gevers, Tom, Vranckx, Luc, Lounis, Nacer, de Jong, Bouke C, Koul, Anil
Published in PloS one (10.07.2014)
Published in PloS one (10.07.2014)
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Journal Article
Molecular mechanism of respiratory syncytial virus fusion inhibitors
Battles, Michael B, Langedijk, Johannes P, Furmanova-Hollenstein, Polina, Chaiwatpongsakorn, Supranee, Costello, Heather M, Kwanten, Leen, Vranckx, Luc, Vink, Paul, Jaensch, Steffen, Jonckers, Tim H M, Koul, Anil, Arnoult, Eric, Peeples, Mark E, Roymans, Dirk, McLellan, Jason S
Published in Nature chemical biology (01.02.2016)
Published in Nature chemical biology (01.02.2016)
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Journal Article
Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase
Haagsma, Anna C, Podasca, Ioana, Koul, Anil, Andries, Koen, Guillemont, Jerome, Lill, Holger, Bald, Dirk
Published in PloS one (17.08.2011)
Published in PloS one (17.08.2011)
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Journal Article
The cytochrome bd-type quinol oxidase is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress
Lu, Ping, Heineke, Marieke H., Koul, Anil, Andries, Koen, Cook, Gregory M., Lill, Holger, van Spanning, Rob, Bald, Dirk
Published in Scientific reports (27.05.2015)
Published in Scientific reports (27.05.2015)
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Journal Article
Diarylquinolines Are Bactericidal for Dormant Mycobacteria as a Result of Disturbed ATP Homeostasis
Koul, Anil, Vranckx, Luc, Dendouga, Najoua, Balemans, Wendy, Van den Wyngaert, Ilse, Vergauwen, Karen, Göhlmann, Hinrich W.H., Willebrords, Rudy, Poncelet, Alain, Guillemont, Jerome, Bald, Dirk, Andries, Koen
Published in The Journal of biological chemistry (12.09.2008)
Published in The Journal of biological chemistry (12.09.2008)
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Journal Article
Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor
Roymans, Dirk, Alnajjar, Sarhad S, Battles, Michael B, Sitthicharoenchai, Panchan, Furmanova-Hollenstein, Polina, Rigaux, Peter, Berg, Joke Van den, Kwanten, Leen, Ginderen, Marcia Van, Verheyen, Nick, Vranckx, Luc, Jaensch, Steffen, Arnoult, Eric, Voorzaat, Richard, Gallup, Jack M., Larios-Mora, Alejandro, Crabbe, Marjolein, Huntjens, Dymphy, Raboisson, Pierre, Langedijk, Johannes P., Ackermann, Mark R., McLellan, Jason S, Vendeville, Sandrine, Koul, Anil
Published in Nature communications (01.08.2017)
Published in Nature communications (01.08.2017)
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Journal Article
Selectivity of TMC207 towards Mycobacterial ATP Synthase Compared with That towards the Eukaryotic Homologue
HAAGSMA, Anna C, ABDILLAHI-IBRAHIM, Rooda, WAGNER, Marijke J, KRAB, Klaas, VERGAUWEN, Karen, GUILLEMONT, Jerome, ANDRIES, Koen, LILL, Holger, KOUL, Anil, BALD, Dirk
Published in Antimicrobial Agents and Chemotherapy (01.03.2009)
Published in Antimicrobial Agents and Chemotherapy (01.03.2009)
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Journal Article
Protein Kinase G from Pathogenic Mycobacteria Promotes Survival within Macrophages
Walburger, Anne, Koul, Anil, Ferrari, Giorgio, Nguyen, Liem, Prescianotto-Baschong, Cristina, Huygen, Kris, Klebl, Bert, Thompson, Charles, Bacher, Gerald, Pieters, Jean
Published in Science (American Association for the Advancement of Science) (18.06.2004)
Published in Science (American Association for the Advancement of Science) (18.06.2004)
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Journal Article
Novel Antibiotics Targeting Respiratory ATP Synthesis in Gram-Positive Pathogenic Bacteria
BALEMANS, Wendy, VRANCKX, Luc, BONROY, Kristien, LILL, Holger, ANDRIES, Koen, BALD, Dirk, KOUL, Anil, VERGAUWEN, Karen, LOUNIS, Nacer, POP, Ovidiu, GUILLEMONT, Jérôme, MOL, Selena, GILISSEN, Ron, MOTTE, Magali, LANCOIS, David, DE BOLLE, Miguel
Published in Antimicrobial Agents and Chemotherapy (01.08.2012)
Published in Antimicrobial Agents and Chemotherapy (01.08.2012)
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Journal Article
Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model
Ispas, Gabriela, Koul, Anil, Verbeeck, Johan, Sheehan, Jennifer, Sanders-Beer, Brigitte, Roymans, Dirk, Andries, Koen, Rouan, Marie-Claude, De Jonghe, Sandra, Bonfanti, Jean-François, Vanstockem, Marc, Simmen, Kenneth, Verloes, Rene
Published in PloS one (26.05.2015)
Published in PloS one (26.05.2015)
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Journal Article
The ATP synthase inhibitor bedaquiline interferes with small-molecule efflux in Mycobacterium smegmatis
Lu, Ping, Villellas, Cristina, Koul, Anil, Andries, Koen, Lill, Holger, Bald, Dirk
Published in Journal of antibiotics (01.12.2014)
Published in Journal of antibiotics (01.12.2014)
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Journal Article
Transcriptional Control of the Mycobacterial embCAB Operon by PknH through a Regulatory Protein, EmbR, In Vivo
SHARMA, Kirti, GUPTA, Meetu, PATHAK, Monika, GUPTA, Nidhi, KOUL, Anil, SARANGI, Smilona, BAWEJA, Renu, SINGH, Yogendra
Published in Journal of Bacteriology (01.04.2006)
Published in Journal of Bacteriology (01.04.2006)
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Journal Article
Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs
Singh, Ramandeep, Rao, Vivek, Shakila, H., Gupta, Radhika, Khera, Aparna, Dhar, Neeraj, Singh, Amit, Koul, Anil, Singh, Yogendra, Naseema, M., Narayanan, P. R., Paramasivan, C. N., Ramanathan, V. D., Tyagi, Anil K.
Published in Molecular microbiology (01.11.2003)
Published in Molecular microbiology (01.11.2003)
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Journal Article
Pharmacokinetics-Pharmacodynamics of a Respiratory Syncytial Virus Fusion Inhibitor in the Cotton Rat Model
ROUAN, Marie-Claude, GEVERS, Tom, ANDRIES, Koen, ROYMANS, Dirk, DE ZWART, Loeckie, NAUWELAERS, David, DE MEULDER, Marc, VAN REMOORTERE, Pieter, VANSTOCKEM, Marc, KOUL, Anil, SIMMEN, Kenny
Published in Antimicrobial Agents and Chemotherapy (01.11.2010)
Published in Antimicrobial Agents and Chemotherapy (01.11.2010)
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Journal Article
Cloning and Characterization of Secretory Tyrosine Phosphatases of Mycobacterium tuberculosis
Koul, A, Choidas, A, Treder, M, Tyagi, A K, Drlica, K, Singh, Y, Ullrich, A
Published in Journal of Bacteriology (01.10.2000)
Published in Journal of Bacteriology (01.10.2000)
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Journal Article
Role of Protein Kinase G in Growth and Glutamine Metabolism of Mycobacterium bovis BCG
NGUYEN, Liem, WALBURGER, Anne, HOUBEN, Edith, KOUL, Anil, MULLER, Stefan, MORBITZER, Monika, KLEBL, Bert, FERRARI, Giorgio, PIETERS, Jean
Published in Journal of Bacteriology (01.08.2005)
Published in Journal of Bacteriology (01.08.2005)
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Journal Article
The possible role of 10398A and 16189C mtDNA variants in providing susceptibility toT2DM in two North Indian populations : a replicative study
BHAT, Audesh, KOUL, Anil, SHARMA, Swarkar, RAI, Ekta, BUKHARI, S. I. A, DHAR, M. K, BAMEZAI, R. N. K
Published in Human genetics (01.02.2007)
Published in Human genetics (01.02.2007)
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