Search Results - "KOUJI HATTORI" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436

Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436

by Hamaguchi, Wataru, Masuda, Naoyuki, Miyamoto, Satoshi, Kikuchi, Shigetoshi, Narazaki, Fumie, Shiina, Yasuhiro, Seo, Ryushi, Amano, Yasushi, Mihara, Takuma, Moriguchi, Hiroyuki, Hattori, Kouji
Published in Bioorganic & medicinal chemistry (01.07.2015)

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A Novel and Potent Poly(ADP-Ribose) Polymerase-1 Inhibitor, FR247304 (5-Chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), Attenuates Neuronal Damage in in Vitro and in Vivo Models of Cerebral Ischemia

A Novel and Potent Poly(ADP-Ribose) Polymerase-1 Inhibitor, FR247304 (5-Chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), Attenuates Neuronal Damage in in Vitro and in Vivo Models of Cerebral Ischemia

by Iwashita, Akinori, Tojo, Nobuteru, Matsuura, Shigeru, Yamazaki, Syunji, Kamijo, Kazunori, Ishida, Junya, Yamamoto, Hirofumi, Hattori, Kouji, Matsuoka, Nobuya, Mutoh, Seitaro
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)

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Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors

Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors

by Iwashita, Akinori, Hattori, Kouji, Yamamoto, Hirofumi, Ishida, Junya, Kido, Yoshiyuki, Kamijo, Kazunori, Murano, Kenji, Miyake, Hiroshi, Kinoshita, Takayoshi, Warizaya, Masaichi, Ohkubo, Mitsuru, Matsuoka, Nobuya, Mutoh, Seitaro
Published in FEBS letters (28.02.2005)

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Neuroprotective Effects of a Novel Poly(ADP-Ribose) Polymerase-1 Inhibitor, 2-{3-[4-(4-Chlorophenyl)-1-piperazinyl] propyl}-4(3H)-quinazolinone (FR255595), in an in Vitro Model of Cell Death and in Mouse 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Model of Parkinson's Disease

Neuroprotective Effects of a Novel Poly(ADP-Ribose) Polymerase-1 Inhibitor, 2-{3-[4-(4-Chlorophenyl)-1-piperazinyl] propyl}-4(3H)-quinazolinone (FR255595), in an in Vitro Model of Cell Death and in Mouse 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Model of Parkinson's Disease

by Iwashita, Akinori, Yamazaki, Syunji, Mihara, Kayoko, Hattori, Kouji, Yamamoto, Hirofumi, Ishida, Junya, Matsuoka, Nobuya, Mutoh, Seitaro
Published in The Journal of pharmacology and experimental therapeutics (01.06.2004)

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Discovery of highly potent and selective biphenylacylsulfonamide-based β3-adrenergic receptor agonists and molecular modeling based on the solved X-ray structure of the β2-adrenergic receptor: Part 6

Discovery of highly potent and selective biphenylacylsulfonamide-based β3-adrenergic receptor agonists and molecular modeling based on the solved X-ray structure of the β2-adrenergic receptor: Part 6

by HATTORI, Kouji, ORITA, Masaya, MATSUI, Shigeo, IMAMURA, Emiko, UESHIMA, Koji, YAMAMOTO, Takao, YAMAMOTO, Nobuhiro, ISHIKAWA, Hirofumi, NAKANO, Keiko, UNAMI, Naoko, HAMADA, Kaori, MATSUMURA, Yasuhiro, TODA, Susumu, TAKAMURA, Fujiko, IMANISHI, Masashi, ITOU, Shinji, NAKAJIMA, Yutaka, TANABE, Daisuke, WASHIZUKA, Kenichi, ARAKI, Takanobu, SAKURAI, Minoru
Published in Bioorganic & medicinal chemistry letters (01.08.2009)

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A New Chiral BLA Promoter for Asymmetric Aza Diels-Alder and Aldol-Type Reactions of Imines

A New Chiral BLA Promoter for Asymmetric Aza Diels-Alder and Aldol-Type Reactions of Imines

by Ishihara, Kazuaki, Miyata, Mayumi, Hattori, Kouji, Tada, Toshiji, Yamamoto, Hisashi
Published in Journal of the American Chemical Society (01.11.1994)

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Discovery of Highly Potent and Selective Biphenylacylsulfonamide-Based β3-Adrenergic Receptor Agonists and Evaluation of Physical Properties as Potential Overactive Bladder Therapies: Part 5

Discovery of Highly Potent and Selective Biphenylacylsulfonamide-Based β3-Adrenergic Receptor Agonists and Evaluation of Physical Properties as Potential Overactive Bladder Therapies: Part 5

by Hattori, Kouji, Toda, Susumu, Imanishi, Masashi, Itou, Shinji, Nakajima, Yutaka, Washizuka, Kenichi, Araki, Takanobu, Hamashima, Hitoshi, Tomishima, Yasuyo, Sakurai, Minoru, Matsui, Shigeo, Imamura, Emiko, Ueshima, Koji, Yamamoto, Takao, Yamamoto, Nobuhiro, Ishikawa, Hirofumi, Nakano, Keiko, Unami, Naoko, Hamada, Kaori, Matsumura, Yasuhiro, Takamura, Fujiko
Published in Journal of medicinal chemistry (14.05.2009)

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A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice

A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice

by Iwashita, Akinori, Mihara, Kayoko, Yamazaki, Syunji, Matsuura, Shigeru, Ishida, Junya, Yamamoto, Hirofumi, Hattori, Kouji, Matsuoka, Nobuya, Mutoh, Seitaro
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)

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Discovery of novel series of benzoic acid derivatives containing biphenyl ether moiety as potent and selective human β3-adrenergic receptor agonists: Part IV

Discovery of novel series of benzoic acid derivatives containing biphenyl ether moiety as potent and selective human β3-adrenergic receptor agonists: Part IV

by NAKAJIMA, Yutaka, IMANISHI, Masashi, YAMAMOTO, Takao, YAMAMOTO, Nobuhiro, ISHIKAWA, Hirofumi, NAKANO, Keiko, UNAMI, Naoko, HAMADA, Kaori, HATTORI, Kouji, ITOU, Shinji, HAMASHIMA, Hitoshi, TOMISHIMA, Yasuyo, WASHIZUKA, Kenichi, SAKURAI, Minoru, MATSUI, Shigeo, IMAMURA, Emiko, UESHIMA, Koji
Published in Bioorganic & medicinal chemistry letters (01.09.2008)

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Highly selective and operationally simple synthesis of enantiomerically pure .beta.-amino esters via double stereodifferentiation

Highly selective and operationally simple synthesis of enantiomerically pure .beta.-amino esters via double stereodifferentiation

by Hattori, Kouji, Miyata, Mayumi, Yamamoto, Hisashi
Published in Journal of the American Chemical Society (01.02.1993)

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Highly selective generation and application of (E)- and (Z)-silyl ketene acetals from .alpha.-hydroxy esters

Highly selective generation and application of (E)- and (Z)-silyl ketene acetals from .alpha.-hydroxy esters

by Hattori, Kouji, Yamamoto, Hisashi
Published in Journal of organic chemistry (01.09.1993)

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Structure and function of a novel coliphage-associated sialidase

Structure and function of a novel coliphage-associated sialidase

by Machida, Yuichi, Miyake, Katsuhide, Hattori, Kouji, Yamamoto, Shin, Kawase, Mitsuo, Iijima, Shinji
Published in FEMS microbiology letters (01.01.2000)

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ASYMMETRIC AZA-DIELS-ALDER REACTION CATALYZED BY BORON REAGENT - EFFECT OF BIPHENOL AND BINAPHTHOL LIGAND

ASYMMETRIC AZA-DIELS-ALDER REACTION CATALYZED BY BORON REAGENT - EFFECT OF BIPHENOL AND BINAPHTHOL LIGAND

by HATTORI, K, YAMAMOTO, H
Published in Synlett (1993)

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Asymmetric aza-Diels-Alder reaction mediated by chiral boron reagent

Asymmetric aza-Diels-Alder reaction mediated by chiral boron reagent

by Hattori, Kouji, Yamamoto, Hisashi
Published in Journal of organic chemistry (01.06.1992)

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Highly selective enolization method for heteroatom substituted esters; its application to the ireland ester enolate claisen rearrangement

Highly selective enolization method for heteroatom substituted esters; its application to the ireland ester enolate claisen rearrangement

by Hattori, Kouji, Yamamoto, Hisashi
Published in Tetrahedron (07.03.1994)

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P2K-27 Novel and potent poly (ADP-ribose) polymerase-1 inhibitors, quinazoli-none and quinoxaline derivatives, ameliorate dopaminergic neuronal damage in mice models of Parkinson's disease

P2K-27 Novel and potent poly (ADP-ribose) polymerase-1 inhibitors, quinazoli-none and quinoxaline derivatives, ameliorate dopaminergic neuronal damage in mice models of Parkinson's disease

by Akinori Iwashita, Kayoko Mihara, Shunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka, Seitaro Mutoh
Published in Journal of Pharmacological Sciences (2006)

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Molecular cloning and characterization of a novel bacteriophage-associated sialidase

Molecular cloning and characterization of a novel bacteriophage-associated sialidase

by Machida, Yuichi, Hattori, Kouji, Miyake, Katsuhide, Kawase, Yuji, Kawase, Mitsuo, Iijima, Shinji
Published in Journal of bioscience and bioengineering (2000)

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Synthesis, SAR study, and biological evaluation of novel quinoline derivatives as phosphodiesterase 10A inhibitors with reduced CYP3A4 inhibition

Synthesis, SAR study, and biological evaluation of novel quinoline derivatives as phosphodiesterase 10A inhibitors with reduced CYP3A4 inhibition

by Hamaguchi, Wataru, Masuda, Naoyuki, Miyamoto, Satoshi, Shiina, Yasuhiro, Kikuchi, Shigetoshi, Mihara, Takuma, Moriguchi, Hiroyuki, Fushiki, Hiroshi, Murakami, Yoshihiro, Amano, Yasushi, Honbou, Kazuya, Hattori, Kouji
Published in Bioorganic & medicinal chemistry (15.01.2015)

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A NOVEL STEREOCONTROLLED SYNTHESIS OF 3-(1'-HYDROXYETHYL)-2-AZETIDINONE

A NOVEL STEREOCONTROLLED SYNTHESIS OF 3-(1'-HYDROXYETHYL)-2-AZETIDINONE

by HATTORI, K, YAMAMOTO, H
Published in Synlett (1993)

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Asymmetric aza-Diels-Alder reaction: enantio- and diastereoselective reaction of imine mediated by Chiral Lewis acid

Asymmetric aza-Diels-Alder reaction: enantio- and diastereoselective reaction of imine mediated by Chiral Lewis acid

by Hattori, Kouji, Yamamoto, Hisashi
Published in Tetrahedron (26.02.1993)

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