Rationale and design of the EMPA-ELDERLY trial: a randomised, double-blind, placebo-controlled, 52-week clinical trial of the efficacy and safety of the sodium–glucose cotransporter-2 inhibitor empagliflozin in elderly Japanese patients with type 2 diabetes
Yabe, Daisuke, Shiki, Kosuke, Suzaki, Keiko, Meinicke, Thomas, Kotobuki, Yutaro, Nishida, Kenichiro, Clark, Douglas, Yasui, Atsutaka, Seino, Yutaka
Published in BMJ open (07.04.2021)
Published in BMJ open (07.04.2021)
Get full text
Journal Article
Cost-effectiveness analysis of empagliflozin in patients with heart failure with reduced ejection fraction in Japan based on the EMPEROR-Reduced trial
Tsutsui, Hiroyuki, Sakamaki, Hiroyuki, Momomura, Shin-ichi, Sakata, Yasushi, Kotobuki, Yutaro, Linden, Stephan, Reifsnider, Odette S., Rakonczai, Pal, Stargardter, Matthew, Murata, Tatsunori, Hirase, Tetsuaki, Nitta, Daisuke
Published in Journal of cardiology (01.06.2023)
Published in Journal of cardiology (01.06.2023)
Get full text
Journal Article
Empagliflozin cost‐effectiveness analysis in Japanese heart failure with mildly reduced and preserved ejection fraction
Tsutsui, Hiroyuki, Sakamaki, Hiroyuki, Momomura, Shin‐ichi, Sakata, Yasushi, Kotobuki, Yutaro, Linden, Stephan, Idehara, Koki, Nitta, Daisuke
Published in ESC Heart Failure (01.02.2024)
Published in ESC Heart Failure (01.02.2024)
Get full text
Journal Article
The SGLT2 inhibitor empagliflozin improves cardiac energy status via mitochondrial ATP production in diabetic mice
Choi, Jungmi, Matoba, Naoki, Setoyama, Daiki, Watanabe, Daiki, Ohnishi, Yuichiro, Yasui, Ryuto, Kitai, Yuichirou, Oomachi, Aki, Kotobuki, Yutaro, Nishiya, Yoichi, Pieper, Michael Paul, Imamura, Hiromi, Yanagita, Motoko, Yamamoto, Masamichi
Published in Communications biology (17.03.2023)
Published in Communications biology (17.03.2023)
Get full text
Journal Article
Abstract 14459: The Cardioprotective Effect on Energy Metabolism of Empagliflozin in Heart of Type 2 Diabetes Model Mouse in vivo
Yamamoto, Masamichi, Kitai, Yuichirou, Yamamoto, Shigenori, Pieper, Michael P, Kotobuki, Yutaro, Yasui, Atsutaka, Yanagita, Motoko
Published in Circulation (New York, N.Y.) (17.11.2020)
Published in Circulation (New York, N.Y.) (17.11.2020)
Get full text
Journal Article
Facile synthesis and fundamental properties of an N-methylguanidine-bridged nucleic acid (GuNA[NMe])Electronic supplementary information (ESI) available. See DOI: 10.1039/c8ob01307a
Horie, Naohiro, Kumagai, Shinji, Kotobuki, Yutaro, Yamaguchi, Takao, Obika, Satoshi
Year of Publication 11.09.2018
Year of Publication 11.09.2018
Get full text
Journal Article
Synthesis and properties of thymidines with six-membered amide bridge
Hari, Yoshiyuki, Osawa, Takashi, Kotobuki, Yutaro, Yahara, Aiko, Shrestha, Ajaya R., Obika, Satoshi
Published in Bioorganic & medicinal chemistry (15.07.2013)
Published in Bioorganic & medicinal chemistry (15.07.2013)
Get full text
Journal Article