Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization
Kosoff, Rachelle E., Aslan, Joseph E., Kostyak, John C., Dulaimi, Essel, Chow, Hoi Yee, Prudnikova, Tatiana Y., Radu, Maria, Kunapuli, Satya P., McCarty, Owen J.T., Chernoff, Jonathan
Published in Blood (07.05.2015)
Published in Blood (07.05.2015)
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Journal Article
Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation
Phee, Hyewon, Au-Yeung, Byron B, Pryshchep, Olga, O'Hagan, Kyle Leonard, Fairbairn, Stephanie Grace, Radu, Maria, Kosoff, Rachelle, Mollenauer, Marianne, Cheng, Debra, Chernoff, Jonathan, Weiss, Arthur
Published in eLife (13.05.2014)
Published in eLife (13.05.2014)
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Journal Article
An in vitro co-culture model of esophageal cells identifies ascorbic acid as a modulator of cell competition
Merlo, Lauren M F, Kosoff, Rachelle E, Gardiner, Kristin L, Maley, Carlo C
Published in BMC cancer (25.10.2011)
Published in BMC cancer (25.10.2011)
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Journal Article
Pak2 Regulates Hematopoietic Progenitor Cell Proliferation, Survival, and Differentiation
Zeng, Yi, Broxmeyer, Hal E., Staser, Karl, Chitteti, Brahmananda Reddy, Park, Su‐Jung, Hahn, Seongmin, Cooper, Scott, Sun, Zejin, Jiang, Li, Yang, XianLin, Yuan, Jin, Kosoff, Rachelle, Sandusky, George, Srour, Edward F., Chernoff, Jonathan, Clapp, D. Wade
Published in Stem cells (Dayton, Ohio) (01.05.2015)
Published in Stem cells (Dayton, Ohio) (01.05.2015)
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Journal Article
561 DuoBody®-PD-L1×4–1BB (GEN1046) induces superior immune-cell activation, cytokine production and cytotoxicity by combining PD-L1 blockade with conditional 4–1BB co-stimulation
Muik, Alexander, Altintas, Isil, Kosoff, Rachelle, Gieseke, Friederike, Schödel, Kristina, Salcedo, Theodora, Burm, Saskia, Toker, Aras, Kranz, Lena, Vormehr, Mathias, Eisel, David, Fereshteh, Mark, Türeci, Özlem, Breij, Esther, Ahmadi, Tahamtan, Sahin, Ugur, Jure-Kunkel, Maria
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
PAK signalling during the development and progression of cancer
Radu, Maria, Semenova, Galina, Kosoff, Rachelle, Chernoff, Jonathan
Published in Nature reviews. Cancer (01.01.2014)
Published in Nature reviews. Cancer (01.01.2014)
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Journal Article
DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death
Thapa, Roshan J., Ingram, Justin P., Ragan, Katherine B., Nogusa, Shoko, Boyd, David F., Benitez, Asiel A., Sridharan, Haripriya, Kosoff, Rachelle, Shubina, Maria, Landsteiner, Vanessa J., Andrake, Mark, Vogel, Peter, Sigal, Luis J., tenOever, Benjamin R., Thomas, Paul G., Upton, Jason W., Balachandran, Siddharth
Published in Cell host & microbe (09.11.2016)
Published in Cell host & microbe (09.11.2016)
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Journal Article
RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus
Nogusa, Shoko, Thapa, Roshan J., Dillon, Christopher P., Liedmann, Swantje, Oguin, Thomas H., Ingram, Justin P., Rodriguez, Diego A., Kosoff, Rachelle, Sharma, Shalini, Sturm, Oliver, Verbist, Katherine, Gough, Peter J., Bertin, John, Hartmann, Boris M., Sealfon, Stuart C., Kaiser, William J., Mocarski, Edward S., López, Carolina B., Thomas, Paul G., Oberst, Andrew, Green, Douglas R., Balachandran, Siddharth
Published in Cell host & microbe (13.07.2016)
Published in Cell host & microbe (13.07.2016)
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Journal Article
Thioredoxin Reductase-1 Mediates Curcumin-Induced Radiosensitization of Squamous Carcinoma Cells
JAVVADI, Prashanthi, HERTAN, Lauren, KOSOFF, Rachelle, DATTA, Tatini, KOLEV, Johann, MICK, Rosemarie, TUTTLE, Stephen W, KOUMENIS, Constantinos
Published in Cancer research (Chicago, Ill.) (01.03.2010)
Published in Cancer research (Chicago, Ill.) (01.03.2010)
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Journal Article
Abstract 1846: DuoBody-CD40×4-1BB (GEN1042) induces dendritic-cell maturation and enhances T-cell activation and effector functions in vitro by conditional CD40 and 4-1BB agonist activity
Muik, Alexander, Kosoff, Rachelle, Gieseke, Friederike, Altintas, Isil, Schödel, Kristina, Burm, Saskia, Stanganello, Eliana, Vascotto, Fulvia, Toker, Aras, Adams, Homer, Breij, Esther, Diken, Mustafa, Ahmadi, Tahamtan, Sasser, Kate, Türeci, Özlem, Fereshteh, Mark, Sahin, Ugur, Jure-Kunkel, Maria
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Pak Signaling in the Development and Progression of Cancer
Radu, Maria, Semenova, Galina, Kosoff, Rachelle, Chernoff, Jonathan
Published in Nature reviews. Cancer (01.01.2014)
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Published in Nature reviews. Cancer (01.01.2014)
Journal Article
A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells
Arias-Romero, L E, Villamar-Cruz, O, Pacheco, A, Kosoff, R, Huang, M, Muthuswamy, S K, Chernoff, J
Published in Oncogene (28.10.2010)
Published in Oncogene (28.10.2010)
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Journal Article
The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment
Dorrance, Adrienne M., De Vita, Serena, Radu, Maria, Reddy, Pavankumar N.G., McGuinness, Meaghan K., Harris, Chad E., Mathieu, Ronald, Lane, Steven W., Kosoff, Rachelle, Milsom, Michael D., Chernoff, Jonathan, Williams, David A.
Published in Blood (28.03.2013)
Published in Blood (28.03.2013)
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Journal Article
Kinase Activity Of Pak2, An Effector Of Rac/CDC42 and Its Interaction With β-PIX Is Required For Murine Hematopoietic Stem Cell Shape, F-Actin Formation, Directional Migration In Vitro and For HSPC Homing To Bone Marrow In Vivo
Reddy, Pavankumar N.G., Wood, Jenna, Harris, Chad E, Xu, Ke, McGuinness, Meaghan, Radu, Maria, Kosoff, Rachelle, Chernoff, Jonathan, Williams, David A.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells
Sela, Meirav, Bogin, Yaron, Beach, Dvora, Oellerich, Thomas, Lehne, Johanna, Smith-Garvin, Jennifer E, Okumura, Mariko, Starosvetsky, Elina, Kosoff, Rachelle, Libman, Evgeny, Koretzky, Gary, Kambayashi, Taku, Urlaub, Henning, Wienands, Jürgen, Chernoff, Jonathan, Yablonski, Deborah
Published in The EMBO journal (03.08.2011)
Published in The EMBO journal (03.08.2011)
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