Function-dependent Conformational Changes of the ABCG2 Multidrug Transporter Modify Its Interaction with a Monoclonal Antibody on the Cell Surface
Özvegy-Laczka, Csilla, Várady, György, Köblös, Gabriella, Ujhelly, Olga, Cervenak, Judit, Schuetz, John D., Sorrentino, Brian P., Koomen, Gerrit-Jan, Váradi, András, Német, Katalin, Sarkadi, Balázs
Published in The Journal of biological chemistry (11.02.2005)
Published in The Journal of biological chemistry (11.02.2005)
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ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
GLAVINAS, Hristos, KIS, Emese, BATHORI, György, VON RICHTER, Oliver, KOOMEN, Gerrit-Jan, KRAJCSI, Péter, PAL, Akos, KOVACS, Rita, JANI, Marton, VAGI, Erika, MOLNAR, Eva, BANSAGHI, Szava, KELE, Zoltan, JANAKY, Tamas
Published in Drug metabolism and disposition (01.09.2007)
Published in Drug metabolism and disposition (01.09.2007)
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Generation of Specific Deoxynojirimycin-type Inhibitors of the Non-lysosomal Glucosylceramidase
Overkleeft, Herman S., Renkema, G. Herma, Neele, Jolanda, Vianello, Paula, Hung, Irene O., Strijland, Anneke, van der Burg, Alida M., Koomen, Gerrit-Jan, Pandit, Upendra K., Aerts, Johannes M.F.G.
Published in The Journal of biological chemistry (09.10.1998)
Published in The Journal of biological chemistry (09.10.1998)
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Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategy
Rodenko, Boris, Wanner, Martin J, Alkhaldi, Abdulsalam A M, Ebiloma, Godwin U, Barnes, Rebecca L, Kaiser, Marcel, Brun, Reto, McCulloch, Richard, Koomen, Gerrit-Jan, de Koning, Harry P
Published in Antimicrobial agents and chemotherapy (01.11.2015)
Published in Antimicrobial agents and chemotherapy (01.11.2015)
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Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C
Allen, John D, van Loevezijn, Arnold, Lakhai, Jeany M, van der Valk, Martin, van Tellingen, Olaf, Reid, Glen, Schellens, Jan H M, Koomen, Gerrit-Jan, Schinkel, Alfred H
Published in Molecular cancer therapeutics (01.04.2002)
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Published in Molecular cancer therapeutics (01.04.2002)
Journal Article
Identification and Development of Biphenyl Substituted Iminosugars as Improved Dual Glucosylceramide Synthase/Neutral Glucosylceramidase Inhibitors
Ghisaidoobe, Amar T, van den Berg, Richard J. B. H. N, Butt, Saleem S, Strijland, Anneke, Donker-Koopman, Wilma E, Scheij, Saskia, van den Nieuwendijk, Adrianus M. C. H, Koomen, Gerrit-Jan, van Loevezijn, Arnold, Leemhuis, Mark, Wennekes, Tom, van der Stelt, Mario, van der Marel, Gijsbert A, van Boeckel, Constant A. A, Aerts, Johannes M. F. G, Overkleeft, Herman S
Published in Journal of medicinal chemistry (13.11.2014)
Published in Journal of medicinal chemistry (13.11.2014)
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Spectral Tuning, Fluorescence, and Photoactivity in Hybrids of Photoactive Yellow Protein, Reconstituted with Native or Modified Chromophores
Kroon, Arthur R., Hoff, Wouter D., Fennema, HermanP. M., Gijzen, Jeroen, Koomen, Gerrit-Jan, Verhoeven, Jan W., Crielaard, Wim, Hellingwerf, Klaas J.
Published in The Journal of biological chemistry (13.12.1996)
Published in The Journal of biological chemistry (13.12.1996)
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Journal Article
Regioselective nitration of purine nucleosides: synthesis of 2-nitroadenosine and 2-nitroinosine
Deghati, Paymaneh Y.F, Wanner, Martin J, Koomen, Gerrit-Jan
Published in Tetrahedron letters (19.02.2000)
Published in Tetrahedron letters (19.02.2000)
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Synthesis of the Cyclostellettamines A−F and Related Bis(3-alkylpyridinium) Macrocycles
Wanner, Martin J., Koomen, Gerrit-Jan
Published in European journal of organic chemistry (01.05.1998)
Published in European journal of organic chemistry (01.05.1998)
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Journal Article
GTP Analogue Inhibits Polymerization and GTPase Activity of the Bacterial Protein FtsZ without Affecting Its Eukaryotic Homologue Tubulin
Läppchen, Tilman, Hartog, Aloysius F, Pinas, Victorine A, Koomen, Gerrit-Jan, den Blaauwen, Tanneke
Published in Biochemistry (Easton) (31.05.2005)
Published in Biochemistry (Easton) (31.05.2005)
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Journal Article
Enantiopure Tetrahydro-β-carbolines via Pictet−Spengler Reactions with N-Sulfinyl Tryptamines
Gremmen, Christiaan, Willemse, Bianca, Wanner, Martin J, Koomen, Gerrit-Jan
Published in Organic letters (29.06.2000)
Published in Organic letters (29.06.2000)
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Journal Article
Synthesis of xestomanzamines A and B
Burm, BEA, Blokker, P, Jongmans, E, van Kampen, E, Wanner, MJ, Koomen, GJ
Published in Heterocycles (01.03.2001)
Published in Heterocycles (01.03.2001)
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Journal Article
Synthesis of Marine-Derived 3-Alkylpyridinium Alkaloids with Potent Antiprotozoal Activity
Rodenko, Boris, Al-Salabi, Mohammed I, Teka, Ibrahim A, Ho, William, El-Sabbagh, Nasser, Ali, Juma A. M, Ibrahim, Hasan M. S, Wanner, Martin J, Koomen, Gerrit-Jan, de Koning, Harry P
Published in ACS medicinal chemistry letters (08.12.2011)
Published in ACS medicinal chemistry letters (08.12.2011)
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Journal Article
Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5′-carboxamidoadenosine analogues
Rodenko, Boris, Detz, Remko J., Pinas, Victorine A., Lambertucci, Catia, Brun, Reto, Wanner, Martin J., Koomen, Gerrit-Jan
Published in Bioorganic & medicinal chemistry (01.03.2006)
Published in Bioorganic & medicinal chemistry (01.03.2006)
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Journal Article
The Mechanism of Selective Purine C-Nitration Revealed: NMR Studies Demonstrate Formation and Radical Rearrangement of an N7-Nitramine Intermediate
Rodenko, Boris, Koch, Melle, van der Burg, Alida M, Wanner, Martin J, Koomen, Gerrit-Jan
Published in Journal of the American Chemical Society (27.04.2005)
Published in Journal of the American Chemical Society (27.04.2005)
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Journal Article
2,N6-Disubstituted Adenosine Analogs with Antitrypanosomal and Antimalarial Activities
RODENKO, Boris, VAN DER BURG, Alida M, WANNER, Martin J, KAISER, Marcel, BRUN, Reto, GOULD, Matthew, DE KONING, Harry P, KOOMEN, Gerrit-Jan
Published in Antimicrobial Agents and Chemotherapy (01.11.2007)
Published in Antimicrobial Agents and Chemotherapy (01.11.2007)
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