L-type calcium channel blocker increases VEGF concentrations in retinal cells and human serum
Kumar, Anmol, Mutter, Stefan, Parente, Erika B, Harjutsalo, Valma, Lithovius, Raija, Mathavan, Sinnakaruppan, Lehto, Markku, Hiltunen, Timo P, Kontula, Kimmo K, Groop, Per-Henrik
Published in PloS one (13.04.2023)
Published in PloS one (13.04.2023)
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Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study design
Nuotio, Marja-Liisa, Sánez Tähtisalo, Heini, Lahtinen, Alexandra, Donner, Kati, Fyhrquist, Frej, Perola, Markus, Kontula, Kimmo K, Hiltunen, Timo P
Published in Epigenetics (02.11.2022)
Published in Epigenetics (02.11.2022)
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Effect of four classes of antihypertensive drugs on cardiac repolarization heterogeneity: A double-blind rotational study
Sánez Tähtisalo, Heini, Hiltunen, Timo P, Kenttä, Tuomas, Junttila, Juhani, Oikarinen, Lasse, Virolainen, Juha, Kontula, Kimmo K, Porthan, Kimmo
Published in PloS one (24.03.2020)
Published in PloS one (24.03.2020)
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Journal Article
Regulation of AT1R expression through HuR by insulin
Paukku, Kirsi, Backlund, Michael, De Boer, Rudolf A, Kalkkinen, Nisse, Kontula, Kimmo K, Lehtonen, Jukka Y A
Published in Nucleic acids research (01.07.2012)
Published in Nucleic acids research (01.07.2012)
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Journal Article
Posttranscriptional regulation of angiotensin II type 1 receptor expression by glyceraldehyde 3-phosphate dehydrogenase
Backlund, Michael, Paukku, Kirsi, Daviet, Laurent, De Boer, Rudolf A, Valo, Erkka, Hautaniemi, Sampsa, Kalkkinen, Nisse, Ehsan, Afshin, Kontula, Kimmo K, Lehtonen, Jukka Y.A
Published in Nucleic acids research (01.04.2009)
Published in Nucleic acids research (01.04.2009)
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Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)
Singh, Sonal, Warren, Helen R, Hiltunen, Timo P, McDonough, Caitrin W, El Rouby, Nihal, Salvi, Erika, Wang, Zhiying, Garofalidou, Tatiana, Fyhrquist, Frej, Kontula, Kimmo K, Glorioso, Valeria, Zaninello, Roberta, Glorioso, Nicola, Pepine, Carl J, Munroe, Patricia B, Turner, Stephan T, Chapman, Arlene B, Boerwinkle, Eric, Johnson, Julie A, Gong, Yan, Cooper-DeHoff, Rhonda M
Published in Journal of the American Heart Association (20.08.2019)
Published in Journal of the American Heart Association (20.08.2019)
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Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients
Rimpelä, Jenni M, Pörsti, Ilkka H, Jula, Antti, Lehtimäki, Terho, Niiranen, Teemu J, Oikarinen, Lasse, Porthan, Kimmo, Tikkakoski, Antti, Virolainen, Juha, Kontula, Kimmo K, Hiltunen, Timo P
Published in BMC medical genetics (04.07.2018)
Published in BMC medical genetics (04.07.2018)
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Genome-wide association study of white-coat effect in hypertensive patients
Rimpelä, Jenni M, Niiranen, Teemu, Jula, Antti, Pörsti, Ilkka H, Tikkakoski, Antti, Havulinna, Aki, Lehtimäki, Terho, Salomaa, Veikko, Kontula, Kimmo K, Hiltunen, Timo P
Published in Blood pressure (04.07.2019)
Published in Blood pressure (04.07.2019)
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CARD15/NOD2 gene variants are associated with familially occurring and complicated forms of Crohn’s disease
Heliö, T, Halme, L, Lappalainen, M, Fodstad, H, Paavola-Sakki, P, Turunen, U, Färkkilä, M, Krusius, T, Kontula, K
Published in Gut (01.04.2003)
Published in Gut (01.04.2003)
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Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol
Fontana, Vanessa, Turner, Richard Myles, Francis, Ben, Yin, Peng, Pütz, Benno, Hiltunen, Timo P, Ruotsalainen, Sanni, Kontula, Kimmo K, Müller-Myhsok, Bertam, Pirmohamed, Munir
Published in Pharmacogenomics and personalized medicine (01.01.2022)
Published in Pharmacogenomics and personalized medicine (01.01.2022)
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Telomere length and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: the LIFE study
Fyhrquist, F, Silventoinen, K, Saijonmaa, O, Kontula, K, Devereux, R B, de Faire, U, Os, I, Dahlöf, B
Published in Journal of human hypertension (01.12.2011)
Published in Journal of human hypertension (01.12.2011)
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Journal Article
p100 increases AT1R expression through interaction with AT1R 3'-UTR
Paukku, Kirsi, Kalkkinen, Nisse, Silvennoinen, Olli, Kontula, Kimmo K, Lehtonen, Jukka Y.A
Published in Nucleic acids research (01.08.2008)
Published in Nucleic acids research (01.08.2008)
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TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives
Chittani, Martina, Zaninello, Roberta, Lanzani, Chiara, Frau, Francesca, Ortu, Maria F, Salvi, Erika, Fresu, Giovanni, Citterio, Lorena, Braga, Daniele, Piras, Daniela A, Carpini, Simona Delli, Velayutham, Dinesh, Simonini, Marco, Argiolas, Giuseppe, Pozzoli, Simona, Troffa, Chiara, Glorioso, Valeria, Kontula, Kimmo K, Hiltunen, Timo P, Donner, Kati M, Turner, Stephen T, Boerwinkle, Eric, Chapman, Arlene B, Padmanabhan, Sandosh, Dominiczak, Anna F, Melander, Olle, Johnson, Julie A, Cooper-Dehoff, Rhonda M, Gong, Yan, Rivera, Natalia V, Condorelli, Gianluigi, Trimarco, Bruno, Manunta, Paolo, Cusi, Daniele, Glorioso, Nicola, Barlassina, Cristina
Published in Journal of hypertension (01.06.2015)
Published in Journal of hypertension (01.06.2015)
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Common Genetic Variants, QT Interval, and Sudden Cardiac Death in a Finnish Population-Based Study
Noseworthy, Peter A, Havulinna, Aki S, Porthan, Kimmo, Lahtinen, Annukka M, Jula, Antti, Karhunen, Pekka J, Perola, Markus, Oikarinen, Lasse, Kontula, Kimmo K, Salomaa, Veikko, Newton-Cheh, Christopher
Published in Circulation. Cardiovascular genetics (01.06.2011)
Published in Circulation. Cardiovascular genetics (01.06.2011)
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Journal Article
Work stress and the long QT syndrome: high job strain and effort-reward imbalance at work associated with arrhythmic risk in the long QT syndrome
Hintsa, Taina, Määttänen, I, Hintsanen, M, Swan, H, Toivonen, L, Kontula, K, Keltikangas-Järvinen, L
Published in Journal of occupational and environmental medicine (01.12.2013)
Published in Journal of occupational and environmental medicine (01.12.2013)
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Mutant ryanodine receptors in catecholaminergic polymorphic ventricular tachycardia generate delayed afterdepolarizations due to increased propensity to Ca2+ waves
Paavola, Jere, Viitasalo, Matti, Laitinen-Forsblom, Päivi J., Pasternack, Michael, Swan, Heikki, Tikkanen, Ilkka, Toivonen, Lauri, Kontula, Kimmo, Laine, Mika
Published in European heart journal (01.05.2007)
Published in European heart journal (01.05.2007)
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Journal Article
Association of celiac disease genes with inflammatory bowel disease in Finnish and Swedish patients
Parmar, A S, Lappalainen, M, Paavola-Sakki, P, Halme, L, Färkkilä, M, Turunen, U, Kontula, K, Aromaa, A, Salomaa, V, Peltonen, L, Halfvarson, J, Törkvist, L, D'Amato, M, Saavalainen, P, Einarsdottir, E
Published in Genes and immunity (01.09.2012)
Published in Genes and immunity (01.09.2012)
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