Pharmacokinetics and Pharmacodynamics of ASP2151, a Helicase-Primase Inhibitor, in a Murine Model of Herpes Simplex Virus Infection
KATSUMATA, Kiyomitsu, CHONO, Koji, KATO, Kota, OHTSU, Yoshiaki, TAKAKURA, Shoji, KONTANI, Toru, SUZUKI, Hiroshi
Published in Antimicrobial Agents and Chemotherapy (01.03.2013)
Published in Antimicrobial Agents and Chemotherapy (01.03.2013)
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Susceptibility of Herpes Simplex Virus Isolated from Genital Herpes Lesions to ASP2151, a Novel Helicase-Primase Inhibitor
KATSUMATA, Kiyomitsu, WEINBERG, Adriana, CHONO, Koji, TAKAKURA, Shoji, KONTANI, Toru, SUZUKI, Hiroshi
Published in Antimicrobial Agents and Chemotherapy (01.07.2012)
Published in Antimicrobial Agents and Chemotherapy (01.07.2012)
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Design, synthesis, and pharmacological evaluation of N-(3-carbamoyl-1H-pyrazol-4-yl)-1,3-oxazole-4-carboxamide derivatives as interleukin-1 receptor-associated kinase 4 inhibitors with reduced potential for cytochrome P450 1A2 induction
Inami, Hiroshi, Mizutani, Tsuyoshi, Watanabe, Junko, Hayashida, Hisashi, Ito, Tomonori, Terasawa, Takeshi, Kontani, Toru, Yamagishi, Hiroaki, Usuda, Hiroyuki, Aoyama, Naohiro, Imamura, Emiko, Ishikawa, Takeshi
Published in Bioorganic & medicinal chemistry (03.05.2023)
Published in Bioorganic & medicinal chemistry (03.05.2023)
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ASP2151, a novel helicase–primase inhibitor, possesses antiviral activity against varicella–zoster virus and herpes simplex virus types 1 and 2
Chono, Koji, Katsumata, Kiyomitsu, Kontani, Toru, Kobayashi, Masayuki, Sudo, Kenji, Yokota, Tomoyuki, Konno, Kenji, Shimizu, Yasuaki, Suzuki, Hiroshi
Published in Journal of antimicrobial chemotherapy (01.08.2010)
Published in Journal of antimicrobial chemotherapy (01.08.2010)
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Novel quinuclidinyl heteroarylcarbamate derivatives as muscarinic receptor antagonists
Nagashima, Shinya, Matsushima, Yuji, Hamaguchi, Hisao, Nagata, Hiroshi, Kontani, Toru, Moritomo, Ayako, Koshika, Tadatsura, Takeuchi, Makoto
Published in Bioorganic & medicinal chemistry (01.07.2014)
Published in Bioorganic & medicinal chemistry (01.07.2014)
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Identification, Synthesis, and Biological Evaluation of 6‑[(6R)‑2-(4-Fluorophenyl)-6-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo[1,5‑a]pyrimidin-3-yl]-2-(2-methylphenyl)pyridazin-3(2H)‑one (AS1940477), a Potent p38 MAP Kinase Inhibitor
Asano, Toru, Yamazaki, Hitoshi, Kasahara, Chiyoshi, Kubota, Hirokazu, Kontani, Toru, Harayama, Yu, Ohno, Kazuki, Mizuhara, Hidekazu, Yokomoto, Masaharu, Misumi, Keiji, Kinoshita, Tomohiko, Ohta, Mitsuaki, Takeuchi, Makoto
Published in Journal of medicinal chemistry (13.09.2012)
Published in Journal of medicinal chemistry (13.09.2012)
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Identification, Synthesis, and Biological Evaluation of 6‑[(6R)‑2-(4-Fluorophenyl)-6-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo[1,5‑a]pyrimidin-3-yl]-2-(2-methylphenyl)pyridazin-3(2H)‑one (AS1940477), a Potent p38 MAP Kinase Inhibitor
Asano, Toru, Yamazaki, Hitoshi, Kasahara, Chiyoshi, Kubota, Hirokazu, Kontani, Toru, Harayama, Yu, Ohno, Kazuki, Mizuhara, Hidekazu, Yokomoto, Masaharu, Misumi, Keiji, Kinoshita, Tomohiko, Ohta, Mitsuaki, Takeuchi, Makoto
Published in Journal of medicinal chemistry (28.08.2014)
Published in Journal of medicinal chemistry (28.08.2014)
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Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors
Nagashima, Shinya, Hondo, Takeshi, Nagata, Hiroshi, Ogiyama, Takashi, Maeda, Jun, Hoshii, Hiroaki, Kontani, Toru, Kuromitsu, Sadao, Ohga, Keiko, Orita, Masaya, Ohno, Kazuki, Moritomo, Ayako, Shiozuka, Koichi, Furutani, Masako, Takeuchi, Makoto, Ohta, Mitsuaki, Tsukamoto, Shin-ichi
Published in Bioorganic & medicinal chemistry (01.10.2009)
Published in Bioorganic & medicinal chemistry (01.10.2009)
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Novel 7 H-pyrrolo[2,3- d]pyrimidine derivatives as potent and orally active STAT6 inhibitors
Nagashima, Shinya, Hondo, Takeshi, Nagata, Hiroshi, Ogiyama, Takashi, Maeda, Jun, Hoshii, Hiroaki, Kontani, Toru, Kuromitsu, Sadao, Ohga, Keiko, Orita, Masaya, Ohno, Kazuki, Moritomo, Ayako, Shiozuka, Koichi, Furutani, Masako, Takeuchi, Makoto, Ohta, Mitsuaki, Tsukamoto, Shin-ichi
Published in Bioorganic & medicinal chemistry (2009)
Published in Bioorganic & medicinal chemistry (2009)
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Studies of non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Synthesis and structure–activity relationships of 2-cyano and 2-hydroxy thiazolidenebenzenesulfonamide derivatives
Masuda, Naoyuki, Yamamoto, Osamu, Fujii, Masahiro, Ohgami, Tetsuro, Fujiyasu, Jiro, Kontani, Toru, Moritomo, Ayako, Orita, Masaya, Kurihara, Hiroyuki, Koga, Hironobu, Kageyama, Shunji, Ohta, Mitsuaki, Inoue, Hiroshi, Hatta, Toshifumi, Shintani, Masafumi, Suzuki, Hiroshi, Sudo, Kenji, Shimizu, Yasuaki, Kodama, Eiichi, Matsuoka, Masao, Fujiwara, Masatoshi, Yokota, Tomoyuki, Shigeta, Shiro, Baba, Masanori
Published in Bioorganic & medicinal chemistry (15.02.2005)
Published in Bioorganic & medicinal chemistry (15.02.2005)
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