Search Results - "KONDRU, RAMA K" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis

Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis

by Lou, Yan, Han, Xiaochun, Kuglstatter, Andreas, Kondru, Rama K., Sweeney, Zachary K., Soth, Michael, McIntosh, Joel, Litman, Renee, Suh, Judy, Kocer, Buelent, Davis, Dana, Park, Jaehyeon, Frauchiger, Sandra, Dewdney, Nolan, Zecic, Hasim, Taygerly, Joshua P., Sarma, Keshab, Hong, Junbae, Hill, Ronald J., Gabriel, Tobias, Goldstein, David M., Owens, Timothy D.
Published in Journal of medicinal chemistry (08.01.2015)

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Journal Article

Kinetic and Thermodynamic Assessment of Binding of Serotonin Transporter Inhibitors

Kinetic and Thermodynamic Assessment of Binding of Serotonin Transporter Inhibitors

by Martin, Renee S, Henningsen, Robert A, Suen, Alexander, Apparsundaram, Subbu, Leung, Becky, Jia, Zhongjiang, Kondru, Rama K, Milla, Marcos E
Published in The Journal of pharmacology and experimental therapeutics (01.12.2008)

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Journal Article

Optical Rotation Computation, Total Synthesis, and Stereochemistry Assignment of the Marine Natural Product Pitiamide A

Optical Rotation Computation, Total Synthesis, and Stereochemistry Assignment of the Marine Natural Product Pitiamide A

by Ribe, Seth, Kondru, Rama K, Beratan, David N, Wipf, Peter
Published in Journal of the American Chemical Society (17.05.2000)

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Journal Article

Bruton’s Tyrosine Kinase Inhibitors: Approaches to Potent and Selective Inhibition, Preclinical and Clinical Evaluation for Inflammatory Diseases and B Cell Malignancies

Bruton’s Tyrosine Kinase Inhibitors: Approaches to Potent and Selective Inhibition, Preclinical and Clinical Evaluation for Inflammatory Diseases and B Cell Malignancies

by Lou, Yan, Owens, Timothy D, Kuglstatter, Andreas, Kondru, Rama K, Goldstein, David M
Published in Journal of medicinal chemistry (24.05.2012)

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Journal Article

Atomic Contributions to the Optical Rotation Angle as a Quantitative Probe of Molecular Chirality

Atomic Contributions to the Optical Rotation Angle as a Quantitative Probe of Molecular Chirality

by Kondru, Rama K., Wipf, Peter, Beratan, David N.
Published in Science (American Association for the Advancement of Science) (18.12.1998)

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Journal Article

Theory-Assisted Determination of Absolute Stereochemistry for Complex Natural Products via Computation of Molar Rotation Angles

Theory-Assisted Determination of Absolute Stereochemistry for Complex Natural Products via Computation of Molar Rotation Angles

by Kondru, Rama K, Wipf, Peter, Beratan, David N
Published in Journal of the American Chemical Society (11.03.1998)

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Finding the perfect spot for fluorine: Improving potency up to 40-fold during a rational fluorine scan of a Bruton's Tyrosine Kinase (BTK) inhibitor scaffold

Finding the perfect spot for fluorine: Improving potency up to 40-fold during a rational fluorine scan of a Bruton's Tyrosine Kinase (BTK) inhibitor scaffold

by Lou, Yan, Sweeney, Zachary K., Kuglstatter, Andreas, Davis, Dana, Goldstein, David M., Han, Xiaochun, Hong, Junbae, Kocer, Buelent, Kondru, Rama K., Litman, Renee, McIntosh, Joel, Sarma, Keshab, Suh, Judy, Taygerly, Joshua, Owens, Timothy D.
Published in Bioorganic & medicinal chemistry letters (15.01.2015)

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Journal Article

Hepatitis C Virus NS5B Polymerase: QM/MM Calculations Show the Important Role of the Internal Energy in Ligand Binding

Hepatitis C Virus NS5B Polymerase: QM/MM Calculations Show the Important Role of the Internal Energy in Ligand Binding

by Parks, Jerry M, Kondru, Rama K, Hu, Hao, Beratan, David N, Yang, Weitao
Published in The journal of physical chemistry. B (13.03.2008)

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Journal Article

Structural and Conformational Dependence of Optical Rotation Angles

Structural and Conformational Dependence of Optical Rotation Angles

by Kondru, Rama K, Wipf, Peter, Beratan, David N
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (19.08.1999)

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Journal Article

Determining Absolute Configuration in Flexible Molecules: A Case Study

Determining Absolute Configuration in Flexible Molecules: A Case Study

by Specht, Kimberly Musa, Nam, Joonwoo, Ho, Douglas M, Berova, Nina, Kondru, Rama K, Beratan, David N, Wipf, Peter, Pascal, Robert A, Kahne, Daniel
Published in Journal of the American Chemical Society (19.09.2001)

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Journal Article

New peroxylactones from the Jamaican sponge Plakinastrella onkodes, with inhibitory activity against the AIDS opportunistic parasitic infection Toxoplasma gondii

New peroxylactones from the Jamaican sponge Plakinastrella onkodes, with inhibitory activity against the AIDS opportunistic parasitic infection Toxoplasma gondii

by Perry, Tony L, Dickerson, Amiee, Khan, Anis A, Kondru, Rama K, Beratan, David N, Wipf, Peter, Kelly, Michelle, Hamann, Mark T
Published in Tetrahedron (18.02.2001)

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Journal Article

INHIBITORS OF BRUTON'S TYROSINE KINASE

INHIBITORS OF BRUTON'S TYROSINE KINASE

by LOU YAN, KONDRU RAMA K, LOPEZ TAPIA FRANCISCO JAVIER, BROTHERTON PLEISS CHRISTINE E
Year of Publication 03.11.2015

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Patent

INHIBITORS OF BRUTON'S TYROSINE KINASE

INHIBITORS OF BRUTON'S TYROSINE KINASE

by LOU YAN, HILGENKAMP RAMONA, KONDRU RAMA K, LOPEZ TAPIA FRANCISCO JAVIER, BROTHERTON PLEISS CHRISTINE E
Year of Publication 20.05.2015

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Patent

NOVEL PHENYLIMIDAZOPYRAZINES

NOVEL PHENYLIMIDAZOPYRAZINES

by LOU YAN, KONDRU RAMA K, SJOGREN ERIC BRIAN, SOTH MICHAEL
Year of Publication 18.03.2011

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Patent

Chiral Action at a Distance: Remote Substituent Effects on the Optical Activity of Calyculins A and B

Chiral Action at a Distance: Remote Substituent Effects on the Optical Activity of Calyculins A and B

by Kondru, Rama K, Beratan, David N, Friestad, Gregory K, Smith, Amos B, Wipf, Peter
Published in Organic letters (01.06.2000)

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Journal Article

PYRROLOPYRAZINE KINASE INHIBITORS

PYRROLOPYRAZINE KINASE INHIBITORS

by HENDRICKS ROBERT THAN, LYNCH STEPHEN M, LOU YAN, KONDRU RAMA K, SOTH MICHAEL, OWENS TIMOTHY D, HERMANN JOHANNES CORNELIUS
Year of Publication 25.02.2013

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Patent

PYRROLOPYRAZINE DERIVATIVES AND THEIR USE AS JAK AND SYK INHIBITORS

PYRROLOPYRAZINE DERIVATIVES AND THEIR USE AS JAK AND SYK INHIBITORS

by HENDRICKS ROBERT THAN, LYNCH STEPHEN M, LOU YAN, KONDRU RAMA K, SOTH MICHAEL, OWENS TIMOTHY D, HERMANN JOHANNES CORNELIUS
Year of Publication 09.01.2013

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Patent

PYRROLOPYRAZINE DERIVATIVES AS SYK AND JAK INHIBITORS

PYRROLOPYRAZINE DERIVATIVES AS SYK AND JAK INHIBITORS

by YEE CALVIN WESLEY, HENDRICKS ROBERT THAN, LYNCH STEPHEN M, LOU YAN, KONDRU RAMA K, SOTH MICHAEL, OWENS TIMOTHY D, HERMANN JOHANNES CORNELIUS
Year of Publication 22.07.2013

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Patent

PYRROLO[2,3-B]PYRAZINE-7-CARBOXAMIDE DERIVATIVES AND THEIR USE AS JAK AND SYK INHIBITORS

PYRROLO[2,3-B]PYRAZINE-7-CARBOXAMIDE DERIVATIVES AND THEIR USE AS JAK AND SYK INHIBITORS

by YEE CALVIN WESLEY, HENDRICKS ROBERT THAN, LYNCH STEPHEN M, LOU YAN, JAIME FIGUEROA SAUL, KONDRU RAMA K, SOTH MICHAEL, OWENS TIMOTHY D, HERMANN JOHANNES CORNELIUS
Year of Publication 22.07.2013

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Patent

INHIBITORS OF BRUTON'S TYROSINE KINASE

INHIBITORS OF BRUTON'S TYROSINE KINASE

by LOU YAN, MORALES OMAR JOSE, KONDRU RAMA K, LOPEZ TAPIA FRANCISCO JAVIER, QIAN YIMIN, OWENS TIMOTHY D, SO SUNG SAU, WANNER JUTTA, THAKKAR KSHITIJ CHHABILBHAI, BILLEDEAU ROLAND J
Year of Publication 04.03.2014

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Patent

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