The mesenchymal context in inflammation, immunity and cancer
Koliaraki, Vasiliki, Prados, Alejandro, Armaka, Marietta, Kollias, George
Published in Nature immunology (01.09.2020)
Published in Nature immunology (01.09.2020)
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Journal Article
RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation
Danks, Lynett, Komatsu, Noriko, Guerrini, Matteo M, Sawa, Shinichiro, Armaka, Marietta, Kollias, George, Nakashima, Tomoki, Takayanagi, Hiroshi
Published in Annals of the rheumatic diseases (01.06.2016)
Published in Annals of the rheumatic diseases (01.06.2016)
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Journal Article
Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells
Jacques, Peggy, Lambrecht, Stijn, Verheugen, Eveline, Pauwels, Elin, Kollias, George, Armaka, Maria, Verhoye, Marleen, Van der Linden, Annemie, Achten, Rik, Lories, Rik J, Elewaut, Dirk
Published in Annals of the rheumatic diseases (01.02.2014)
Published in Annals of the rheumatic diseases (01.02.2014)
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Journal Article
Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche
Roulis, Manolis, Kaklamanos, Aimilios, Schernthanner, Marina, Bielecki, Piotr, Zhao, Jun, Kaffe, Eleanna, Frommelt, Laura-Sophie, Qu, Rihao, Knapp, Marlene S., Henriques, Ana, Chalkidi, Niki, Koliaraki, Vasiliki, Jiao, Jing, Brewer, J. Richard, Bacher, Maren, Blackburn, Holly N., Zhao, Xiaoyun, Breyer, Richard M., Aidinis, Vassilis, Jain, Dhanpat, Su, Bing, Herschman, Harvey R., Kluger, Yuval, Kollias, George, Flavell, Richard A.
Published in Nature (London) (23.04.2020)
Published in Nature (London) (23.04.2020)
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Journal Article
Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis
Cambré, Isabelle, Gaublomme, Djoere, Burssens, Arne, Jacques, Peggy, Schryvers, Nadia, De Muynck, Amélie, Meuris, Leander, Lambrecht, Stijn, Carter, Shea, de Bleser, Pieter, Saeys, Yvan, Van Hoorebeke, Luc, Kollias, George, Mack, Matthias, Simoens, Paul, Lories, Rik, Callewaert, Nico, Schett, Georg, Elewaut, Dirk
Published in Nature communications (05.11.2018)
Published in Nature communications (05.11.2018)
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Journal Article
Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
Frank-Bertoncelj, Mojca, Trenkmann, Michelle, Klein, Kerstin, Karouzakis, Emmanuel, Rehrauer, Hubert, Bratus, Anna, Kolling, Christoph, Armaka, Maria, Filer, Andrew, Michel, Beat A., Gay, Renate E., Buckley, Christopher D., Kollias, George, Gay, Steffen, Ospelt, Caroline
Published in Nature communications (23.03.2017)
Published in Nature communications (23.03.2017)
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Journal Article
ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts
Yan, Minglu, Komatsu, Noriko, Muro, Ryunosuke, Huynh, Nam Cong-Nhat, Tomofuji, Yoshihiko, Okada, Yukinori, Suzuki, Hiroshi I., Takaba, Hiroyuki, Kitazawa, Riko, Kitazawa, Sohei, Pluemsakunthai, Warunee, Mitsui, Yuichi, Satoh, Takashi, Okamura, Tadashi, Nitta, Takeshi, Im, Sin-Hyeog, Kim, Chan Johng, Kollias, George, Tanaka, Sakae, Okamoto, Kazuo, Tsukasaki, Masayuki, Takayanagi, Hiroshi
Published in Nature immunology (01.09.2022)
Published in Nature immunology (01.09.2022)
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Journal Article
Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia
Boillée, Séverine, Yamanaka, Koji, Lobsiger, Christian S, Copeland, Neal G, Jenkins, Nancy A, Kassiotis, George, Kollias, George, Cleveland, Don W
Published in Science (American Association for the Advancement of Science) (02.06.2006)
Published in Science (American Association for the Advancement of Science) (02.06.2006)
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Journal Article
Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma
Kerdidani, Dimitra, Chouvardas, Panagiotis, Arjo, Ares Rocanin, Giopanou, Ioanna, Ntaliarda, Giannoula, Guo, Yu Amanda, Tsikitis, Mary, Kazamias, Georgios, Potaris, Konstantinos, Stathopoulos, Georgios T., Zakynthinos, Spyros, Kalomenidis, Ioannis, Soumelis, Vassili, Kollias, George, Tsoumakidou, Maria
Published in Nature communications (29.03.2019)
Published in Nature communications (29.03.2019)
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Journal Article
Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology
Roulis, Manolis, Armaka, Maria, Manoloukos, Menelaos, Apostolaki, Maria, Kollias, George
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2011)
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Journal Article
Blockade of TNF-α rapidly inhibits pain responses in the central nervous system
Hess, Andreas, Axmann, Roland, Rech, Juergen, Finzel, Stefanie, Heindl, Cornelia, Kreitz, Silke, Sergeeva, Marina, Saake, Marc, Garcia, Meritxell, Kollias, George, Straub, Rainer H, Sporns, Olaf, Doerfler, Arnd, Brune, Kay, Schett, Georg
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2011)
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Journal Article
In Silico Identification and Evaluation of Natural Products as Potential Tumor Necrosis Factor Function Inhibitors Using Advanced Enalos Asclepios KNIME Nodes
Papadopoulou, Dimitra, Drakopoulos, Antonios, Lagarias, Panagiotis, Melagraki, Georgia, Kollias, George, Afantitis, Antreas
Published in International journal of molecular sciences (23.09.2021)
Published in International journal of molecular sciences (23.09.2021)
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Journal Article
Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL)
Melagraki, Georgia, Ntougkos, Evangelos, Rinotas, Vagelis, Papaneophytou, Christos, Leonis, Georgios, Mavromoustakos, Thomas, Kontopidis, George, Douni, Eleni, Afantitis, Antreas, Kollias, George
Published in PLoS computational biology (01.04.2017)
Published in PLoS computational biology (01.04.2017)
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Journal Article
Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases
Armaka, Maria, Apostolaki, Maria, Jacques, Peggy, Kontoyiannis, Dimitris L, Elewaut, Dirk, Kollias, George
Published in The Journal of experimental medicine (18.02.2008)
Published in The Journal of experimental medicine (18.02.2008)
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Journal Article
Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice
Papazian, Irini, Tsoukala, Eleni, Boutou, Athena, Karamita, Maria, Kambas, Konstantinos, Iliopoulou, Lida, Fischer, Roman, Kontermann, Roland E, Denis, Maria C, Kollias, George, Lassmann, Hans, Probert, Lesley
Published in Journal of neuroinflammation (26.09.2021)
Published in Journal of neuroinflammation (26.09.2021)
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Journal Article
Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis
Nikitopoulou, Ioanna, Oikonomou, Nikos, Karouzakis, Emmanuel, Sevastou, Ioanna, Nikolaidou-Katsaridou, Nefeli, Zhao, Zhenwen, Mersinias, Vassilis, Armaka, Maria, Xu, Yan, Masu, Masayuki, Mills, Gordon B, Gay, Steffen, Kollias, George, Aidinis, Vassilis
Published in The Journal of experimental medicine (07.05.2012)
Published in The Journal of experimental medicine (07.05.2012)
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