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Synthesis and Evaluation of 1H-Pyrrolo[2,3-b]pyridine Derivatives as Novel Immunomodulators Targeting Janus Kinase 3

Synthesis and Evaluation of 1H-Pyrrolo[2,3-b]pyridine Derivatives as Novel Immunomodulators Targeting Janus Kinase 3

by Nakajima, Yutaka, Tojo, Takashi, Morita, Masataka, Hatanaka, Keiko, Shirakami, Shohei, Tanaka, Akira, Sasaki, Hiroshi, Nakai, Kazuo, Mukoyoshi, Koichiro, Hamaguchi, Hisao, Takahashi, Fumie, Moritomo, Ayako, Higashi, Yasuyuki, Inoue, Takayuki
Published in Chemical & pharmaceutical bulletin (01.05.2015)

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Journal Article

The '2+1' Construction of Homooxacalix[3]arenes Possessing Different Substituents on Their Upper Rims

The '2+1' Construction of Homooxacalix[3]arenes Possessing Different Substituents on Their Upper Rims

by TSUBAKI, Kazunori, MUKOYOSHI, Koichiro, OTSUBO, Tadamune, FUJI, Kaoru
Published in Chemical & pharmaceutical bulletin (01.06.2000)

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Journal Article

Discovery and biological evaluation of novel pyrazolopyridine derivatives as potent and orally available PI3Kδ inhibitors

Discovery and biological evaluation of novel pyrazolopyridine derivatives as potent and orally available PI3Kδ inhibitors

by Hamajima, Toshihiro, Takahashi, Fumie, Kato, Koji, Mukoyoshi, Koichiro, Yoshihara, Kousei, Yamaki, Susumu, Sugano, Yukihito, Moritomo, Ayako, Yamagami, Kaoru, Yokoo, Koji, Fukahori, Hidehiko
Published in Bioorganic & medicinal chemistry (15.05.2018)

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Journal Article

Optimization of 2,4-diamino-5-fluoropyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug–drug interactions and P-gp liability

Optimization of 2,4-diamino-5-fluoropyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug–drug interactions and P-gp liability

by Kunikawa, Shigeki, Tanaka, Akira, Mukoyoshi, Koichiro, Nagashima, Shinya, Tominaga, Hiroaki, Chida, Noboru, Tasaki, Mamoru, Shirai, Fumiyuki
Published in Bioorganic & medicinal chemistry (01.07.2015)

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Journal Article

Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3

Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3

by Nakajima, Yutaka, Inoue, Takayuki, Nakai, Kazuo, Mukoyoshi, Koichiro, Hamaguchi, Hisao, Hatanaka, Keiko, Sasaki, Hiroshi, Tanaka, Akira, Takahashi, Fumie, Kunikawa, Shigeki, Usuda, Hiroyuki, Moritomo, Ayako, Higashi, Yasuyuki, Inami, Masamichi, Shirakami, Shohei
Published in Bioorganic & medicinal chemistry (01.08.2015)

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Journal Article

Corrigendum to “Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3” [Bioorg. Med. Chem. 23 (2015) 4871–4883]

Corrigendum to “Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3” [Bioorg. Med. Chem. 23 (2015) 4871–4883]

by Nakajima, Yutaka, Inoue, Takayuki, Nakai, Kazuo, Mukoyoshi, Koichiro, Hamaguchi, Hisao, Hatanaka, Keiko, Sasaki, Hiroshi, Tanaka, Akira, Takahashi, Fumie, Kunikawa, Shigeki, Usuda, Hiroyuki, Moritomo, Ayako, Higashi, Yasuyuki, Inami, Masamichi, Shirakami, Shohei
Published in Bioorganic & medicinal chemistry (15.05.2017)

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Journal Article

Corrigendum to “Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3” [Bioorg. Med. Chem. 23 (2015) 4871–4883]

Corrigendum to “Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3” [Bioorg. Med. Chem. 23 (2015) 4871–4883]

by Nakajima, Yutaka, Inoue, Takayuki, Nakai, Kazuo, Mukoyoshi, Koichiro, Hamaguchi, Hisao, Hatanaka, Keiko, Sasaki, Hiroshi, Tanaka, Akira, Takahashi, Fumie, Kunikawa, Shigeki, Usuda, Hiroyuki, Moritomo, Ayako, Higashi, Yasuyuki, Inami, Masamichi, Shirakami, Shohei
Published in Bioorganic & medicinal chemistry (15.09.2016)

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Journal Article

Enantiomeric recognition of amino acids using a chiral spiropyran derivative

Enantiomeric recognition of amino acids using a chiral spiropyran derivative

by Tsubaki, Kazunori, Mukoyoshi, Koichiro, Morikawa, Hiroshi, Kinoshita, Takayoshi, Fuji, Kaoru
Published in Chirality (New York, N.Y.) (2002)

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Journal Article

Cristal de sal de un compuesto de piridina fusionado

Cristal de sal de un compuesto de piridina fusionado

by YASUDA, Hironobu, MUKOYOSHI, Koichiro, KIKUCHI, Takashi, GATO, Katsuhiko, KAWAKAMI, Takeshi, KITAMURA, Tsuyoshi
Year of Publication 14.04.2016

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Patent

CRYSTAL OF FUSED PYRIDINE COMPOUND SALT

CRYSTAL OF FUSED PYRIDINE COMPOUND SALT

by KAWAKAMI, TAKESHI, GATO, KATSUHIKO, MUKOYOSHI, KOICHIRO, KITAMURA, TSUYOSHI, YASUDA, HIRONOBU, KIKUCHI, TAKASHI
Year of Publication 24.02.2016

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Patent

composto 2,4-diaminopirimidina

composto 2,4-diaminopirimidina

by KOICHIRO MUKOYOSHI, SHIGEKI KUNIKAWA, JUN MAEDA, AKIRA TANAKA, YUJI TAKASUNA, SHINYA NAGASHIMA, NOBORU CHIDA
Year of Publication 01.12.2015

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Patent

Crystal of fused pyridine compound salt

Crystal of fused pyridine compound salt

by KITAMURA TSUYOSHI, GATO KATSUHIKO, KIKUCHI TAKASHI, YASUDA HIRONOBU, MUKOYOSHI KOICHIRO, KAWAKAMI TAKESHI
Year of Publication 15.07.2014

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Patent

compostos de piridina condensados ou sais farmaceuticamente aceitáveis dos mesmos, medicamentos, inibidor da jak3 e produto compreendendo os referidos compostos

compostos de piridina condensados ou sais farmaceuticamente aceitáveis dos mesmos, medicamentos, inibidor da jak3 e produto compreendendo os referidos compostos

by Kazuo Nakai, Yasuyuki Higashi, Shigeki Kunika Wa, Yutaka Nakajima, Taka Yuki Inoue, Hisao Hamaguchi, Shohei Shirakami, Akira Tanaka, Fumie Takahashi, Keiko Hatanaka, Koichiro Mukoyoshi, Hiroshi Sasaki
Year of Publication 25.05.2021

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Patent

CRYSTAL OF FUSED PYRIDINE COMPOUND SALT

CRYSTAL OF FUSED PYRIDINE COMPOUND SALT

by KAWAKAMI, TAKESHI, GATO, KATSUHIKO, MUKOYOSHI, KOICHIRO, KITAMURA, TSUYOSHI, YASUDA, HIRONOBU, KIKUCHI, TAKASHI
Year of Publication 15.01.2014

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Patent

compostos de piridina condensados ou sais farmaceuticamente aceitáveis dos mesmos, medicamentos, inibidor da jak3 e produto compreendendo os referidos compostos

compostos de piridina condensados ou sais farmaceuticamente aceitáveis dos mesmos, medicamentos, inibidor da jak3 e produto compreendendo os referidos compostos

by Kazuo Nakai, Yasuyuki Higashi, Shigeki Kunika Wa, Yutaka Nakajima, Taka Yuki Inoue, Hisao Hamaguchi, Shohei Shirakami, Akira Tanaka, Fumie Takahashi, Keiko Hatanaka, Koichiro Mukoyoshi, Hiroshi Sasaki
Year of Publication 17.11.2020

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Patent

CRYSTAL OF FUSED PYRIDINE COMPOUND SALT

CRYSTAL OF FUSED PYRIDINE COMPOUND SALT

by KAWAKAMI, TAKESHI, GATO, KATSUHIKO, MUKOYOSHI, KOICHIRO, KITAMURA, TSUYOSHI, YASUDA, HIRONOBU, KIKUCHI, TAKASHI
Year of Publication 15.05.2013

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Patent

CRYSTAL OF FUSED PYRIDINE COMPOUND SALT

CRYSTAL OF FUSED PYRIDINE COMPOUND SALT

by KITAMURA TSUYOSHI, GATO KATSUHIKO, KIKUCHI TAKASHI, YASUDA HIRONOBU, MUKOYOSHI KOICHIRO, KAWAKAMI TAKESHI
Year of Publication 25.04.2013

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Patent

HETEROCYCLIC JANUS KINASE 3 INHIBITORS

HETEROCYCLIC JANUS KINASE 3 INHIBITORS

by HAMAGUCHI, HISAO, TANAKA, AKIRA, HATANAKA, KEIKO, INOUE, TAKAYUKI, KUNIKAWA, SHIGEKI, SASAKI, HIROSHI, TAKAHASHI, FUMIE, MUKOYOSHI, KOICHIRO, HIGASHI, YASUYUKI, NAKAI, KAZUO, SHIRAKAMI, SHOHEI, NAKAJIMA, YUTAKA
Year of Publication 30.04.2015

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Patent

HETEROCYCLIC JANUS KINASE 3 INHIBITORS

HETEROCYCLIC JANUS KINASE 3 INHIBITORS

by SASAKI HIROSHI, NAKAI KAZUO, TANAKA AKIRA, NAKAJIMA YUTAKA, HIGASHI YASUYUKI, MUKOYOSHI KOICHIRO, HAMAGUCHI HISAO, TAKAHASHI FUMIE, SHIRAKAMI SHOHEI, HATANAKA KEIKO, KUNIKAWA SHIGEKI, INOUE TAKAYUKI
Year of Publication 27.02.2015

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Patent

HETEROCYKLISKE JANUS KINASE 3-INHIBITORER

HETEROCYKLISKE JANUS KINASE 3-INHIBITORER

by HAMAGUCHI, HISAO, TANAKA, AKIRA, HATANAKA, KEIKO, INOUE, TAKAYUKI, KUNIKAWA, SHIGEKI, SASAKI, HIROSHI, TAKAHASHI, FUMIE, MUKOYOSHI, KOICHIRO, HIGASHI, YASUYUKI, NAKAI, KAZUO, SHIRAKAMI, SHOHEI, NAKAJIMA, YUTAKA
Year of Publication 05.01.2015

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Patent