eIF2B activator prevents neurological defects caused by a chronic integrated stress response
Wong, Yao Liang, LeBon, Lauren, Basso, Ana M, Kohlhaas, Kathy L, Nikkel, Arthur L, Robb, Holly M, Donnelly-Roberts, Diana L, Prakash, Janani, Swensen, Andrew M, Rubinstein, Nimrod D, Krishnan, Swathi, McAllister, Fiona E, Haste, Nicole V, O'Brien, Jonathon J, Roy, Margaret, Ireland, Andrea, Frost, Jennifer M, Shi, Lei, Riedmaier, Stephan, Martin, Kathleen, Dart, Michael J, Sidrauski, Carmela
Published in eLife (09.01.2019)
Published in eLife (09.01.2019)
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An Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor Possessing Cognition-Enhancing Properties in Vivo
Timmermann, Daniel B., Grønlien, Jens Halvard, Kohlhaas, Kathy L., Nielsen, Elsebet Ø., Dam, Eva, Jørgensen, Tino D., Ahring, Philip K., Peters, Dan, Holst, Dorte, Chrsitensen, Jeppe K., Malysz, John, Briggs, Clark A., Gopalakrishnan, Murali, Olsen, Gunnar M.
Published in The Journal of pharmacology and experimental therapeutics (01.10.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2007)
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Journal Article
Preclinical abuse liability assessment of ABT-126, an agonist at the α7 nicotinic acetylcholine receptor (nAChR)
Hudzik, Thomas J, Basso, Ana M, Lynch, 3rd, James J, Bracken, William M, Mohler, Eric G, Kohlhaas, Kathy L, Xu, Hongyu, Haig, George, Gault, Laura
Published in Pharmacology, biochemistry and behavior (01.07.2017)
Published in Pharmacology, biochemistry and behavior (01.07.2017)
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Journal Article
Impact of neonatal NOS-1 inhibitor exposure on neurobehavioural measures and prefrontal-temporolimbic integration in the rat nucleus accumbens
Dec, Alexander M., Kohlhaas, Kathy L., Nelson, Christopher L., Hoque, Kristina E., Leilabadi, Solmaz N., Folk, Jessica, Wolf, Marina E., West, Anthony R.
Published in The international journal of neuropsychopharmacology (01.02.2014)
Published in The international journal of neuropsychopharmacology (01.02.2014)
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Journal Article
Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia
RUETER, Lynne E, BALLARD, Michael E, GALLAGHER, Kelly B, BASSO, Ana Maria, CURZON, Peter, KOHLHAAS, Kathy L
Published in Psychopharmacologia (01.11.2004)
Published in Psychopharmacologia (01.11.2004)
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Journal Article
4-Amino-5-aryl-6-arylethynylpyrimidines: Structure–activity relationships of non-nucleoside adenosine kinase inhibitors
Matulenko, Mark A., Paight, Ernest S., Frey, Robin R., Gomtsyan, Arthur, DiDomenico, Stanley, Jiang, Meiqun, Lee, Chih-Hung, Stewart, Andrew O., Yu, Haixia, Kohlhaas, Kathy L., Alexander, Karen M., McGaraughty, Steve, Mikusa, Joseph, Marsh, Kennan C., Muchmore, Steven W., Jakob, Clarissa L., Kowaluk, Elizabeth A., Jarvis, Michael F., Bhagwat, Shripad S.
Published in Bioorganic & medicinal chemistry (15.02.2007)
Published in Bioorganic & medicinal chemistry (15.02.2007)
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Journal Article
Effect of dopamine D3 antagonists on PPI in DBA/2J mice or PPI deficit induced by neonatal ventral hippocampal lesions in rats
MIN ZHANG, BALLARD, Michael E, RUETER, Lynne E, KOHLHAAS, Kathy L, BROWMAN, Kaitlin E, JONGEN-RELO, Ana-Lucia, UNGER, Liliane V, FOX, Gerard B, GROSS, Gerhard, DECKER, Michael W, DRESCHER, Karla U
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2006)
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2006)
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Journal Article
5-(3-Bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine: structure–activity relationships of 7-substituted heteroaryl analogs as non-nucleoside adenosine kinase inhibitors
Matulenko, Mark A., Lee, Chih-Hung, Jiang, Meiqun, Frey, Robin R., Cowart, Marlon D., Bayburt, Erol K., DiDomenico, Stanley, Gfesser, Gregory A., Gomtsyan, Arthur, Zheng, Guo Zhu, McKie, Jeffery A., Stewart, Andrew O., Yu, Haixia, Kohlhaas, Kathy L., Alexander, Karen M., McGaraughty, Steve, Wismer, Carol T., Mikusa, Joseph, Marsh, Kennan C., Snyder, Ronald D., Diehl, Marilyn S., Kowaluk, Elizabeth A., Jarvis, Michael F., Bhagwat, Shripad S.
Published in Bioorganic & medicinal chemistry (01.06.2005)
Published in Bioorganic & medicinal chemistry (01.06.2005)
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Journal Article
Synthesis and biological evaluation of 6,7-disubstituted 4-aminopyrido[2,3- d]pyrimidines as adenosine kinase inhibitors
Perner, Richard J., Lee, Chih-Hung, Jiang, Meiqun, Gu, Yu-Gui, DiDomenico, Stanley, Bayburt, Erol K., Alexander, Karen M., Kohlhaas, Kathy L., Jarvis, Michael F., Kowaluk, Elizabeth L., Bhagwat, Shripad S.
Published in Bioorganic & medicinal chemistry letters (02.06.2005)
Published in Bioorganic & medicinal chemistry letters (02.06.2005)
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Journal Article
Synthesis and Structure−Activity Relationships of 3,8-Diazabicyclo[4.2.0]octane Ligands, Potent Nicotinic Acetylcholine Receptor Agonists
Frost (née Pac, Jennifer M, Bunnelle, William H, Tietje, Karin R, Anderson, David J, Rueter, Lynne E, Curzon, Peter, Surowy, Carol S, Ji, Jianquo, Daanen, Jerome F, Kohlhaas, Kathy L, Buckley, Michael J, Henry, Rodger F, Dyhring, Tino, Ahring, Philip K, Meyer, Michael D
Published in Journal of medicinal chemistry (28.12.2006)
Published in Journal of medicinal chemistry (28.12.2006)
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Journal Article
Loss of functional neuronal nicotinic receptors in dorsal root ganglion neurons in a rat model of neuropathic pain
Dubé, Gilles R., Kohlhaas, Kathy L., Rueter, Lynne E., Surowy, Carol S., Meyer, Michael D., Briggs, Clark A.
Published in Neuroscience letters (07.03.2005)
Published in Neuroscience letters (07.03.2005)
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Journal Article
5,6,7-Trisubstituted 4-Aminopyrido[2,3-d]pyrimidines as Novel Inhibitors of Adenosine Kinase
Perner, Richard J, Gu, Yu-Gui, Lee, Chih-Hung, Bayburt, Erol K, McKie, Jeffery, Alexander, Karen M, Kohlhaas, Kathy L, Wismer, Carol T, Mikusa, Joe, Jarvis, Michael F, Kowaluk, Elizabeth A, Bhagwat, Shripad S
Published in Journal of medicinal chemistry (20.11.2003)
Published in Journal of medicinal chemistry (20.11.2003)
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Journal Article
Structure–activity studies of 5-substituted pyridopyrimidines as adenosine kinase inhibitors
Cowart, Marlon, Lee, Chih-Hung, Gfesser, Gregory A., Bayburt, Erol K., Bhagwat, Shripad S., Stewart, Andrew O., Yu, Haixia, Kohlhaas, Kathy L., McGaraughty, Steve, Wismer, Carol T., Mikusa, Joseph, Zhu, Chang, Alexander, Karen M., Jarvis, Michael F., Kowaluk, Elizabeth A.
Published in Bioorganic & medicinal chemistry letters (08.01.2001)
Published in Bioorganic & medicinal chemistry letters (08.01.2001)
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Journal Article
Induction by endotoxin of nitric oxide synthase in the rat mesentery: lack of effect on action of vasoconstrictors
Mitchell, Jane A., Kohlhaas, Kathy L., Sorrentino, Raffaella, Warner, Timothy D., Murad, Ferid, Vane, John R.
Published in British journal of pharmacology (01.05.1993)
Published in British journal of pharmacology (01.05.1993)
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