The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, Capecitabine
SHIMMA, N, UMEDA, I, KURUMA, I, HORII, I, ISHITSUKA, H, ARASAKI, M, MURASAKI, C, MASUBUCHI, K, KOHCHI, Y, MIWA, M, URA, M, SAWADA, N, TAHARA, H
Published in Bioorganic & medicinal chemistry (01.07.2000)
Published in Bioorganic & medicinal chemistry (01.07.2000)
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Discovery of CH7057288 as an Orally Bioavailable, Selective, and Potent pan-TRK Inhibitor
Ito, Toshiya, Kinoshita, Kazutomo, Tomizawa, Masaki, Shinohara, Shojiro, Nishii, Hiroki, Matsushita, Masayuki, Hattori, Kazuo, Kohchi, Yasunori, Kohchi, Masami, Hayase, Tadakatsu, Watanabe, Fumio, Hasegawa, Kiyoshi, Tanaka, Hiroshi, Kuramoto, Shino, Takanashi, Kenji, Oikawa, Nobuhiro
Published in Journal of medicinal chemistry (22.09.2022)
Published in Journal of medicinal chemistry (22.09.2022)
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Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent
Isshiki, Yoshiaki, Kohchi, Yasunori, Iikura, Hitoshi, Matsubara, Yasuaki, Asoh, Kohsuke, Murata, Takeshi, Kohchi, Masami, Mizuguchi, Eisaku, Tsujii, Shinji, Hattori, Kazuo, Miura, Takaaki, Yoshimura, Yasushi, Aida, Satoshi, Miwa, Masanori, Saitoh, Ryoichi, Murao, Naoaki, Okabe, Hisafumi, Belunis, Charles, Janson, Cheryl, Lukacs, Christine, Schück, Verena, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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ORALLY ADMINISTRABLE VIRIDIOFUNGIN DERIVATIVE HAVING ANTI-HCV ACTIVITY
NAKAMA, KIMITAKA, KOHCHI, YASUNORI, KOMIYAMA, SUSUMU, WATANABE, FUMIO
Year of Publication 20.02.2014
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Year of Publication 20.02.2014
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Design and synthesis of novel prodrugs of 2′-deoxy-2′-methylidenecytidine activated by membrane dipeptidase overexpressed in tumor tissues
Kohchi, Yasunori, Hattori, Kazuo, Oikawa, Nobuhiro, Mizuguchi, Eisaku, Isshiki, Yoshiaki, Aso, Kohsuke, Yoshinari, Kiyoshi, Shirai, Haruyoshi, Miwa, Masanori, Inagaki, Yukiko, Ura, Masako, Ogawa, Kotaroh, Okabe, Hisafumi, Ishitsuka, Hideo, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
Published in Bioorganic & medicinal chemistry letters (15.04.2007)
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PROCESS FOR PRODUCTION OF 2,3,4-TRIFLUORO-5-(IODO OR BROMO)BENZOIC ACID
KOYANO, HIROSHI, KOHCHI, YASUNORI, ISSHIKI, YOSHIAKI, IIKURA, HITOSHI
Year of Publication 19.10.2006
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Year of Publication 19.10.2006
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Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine
Hattori, Kazuo, Kohchi, Yasunori, Oikawa, Nobuhiro, Suda, Hitomi, Ura, Masako, Ishikawa, Tohru, Miwa, Masanori, Endoh, Mika, Eda, Hiroyuki, Tanimura, Hiromi, Kawashima, Akira, Horii, Ikuo, Ishitsuka, Hideo, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
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NOVEL 4-PHENYLAMINO-BENZALDOXIME DERIVATIVE AND USE THEREOF AS MEK INHIBITOR
SHIMMA, NOBUO, MATSUBARA, YASUAKI, MIWA, MASANORI, HATTORI, KAZUO, INAGAKI, NAOHITO, KOHCHI, YASUNORI, ISSHIKI, YOSHIAKI, IIKURA, HITOSHI
Year of Publication 31.03.2005
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Year of Publication 31.03.2005
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Synthesis and structure–activity relationships of novel fungal chitin synthase inhibitors
Masubuchi, Kazunao, Taniguchi, Mikio, Umeda, Isao, Hattori, Kazuo, Suda, Hitomi, Kohchi, Yasunori, Isshiki, Yoshiaki, Sakai, Toshiya, Kohchi, Masami, Shirai, Michio, Okabe, Hisafumi, Sudoh, Masayuki, Yamazaki, Toshikazu, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (03.07.2000)
Published in Bioorganic & medicinal chemistry letters (03.07.2000)
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5-SUBSTITUTED-2-PHENYLAMINO-BENZAMIDE AS MEK INHIBITOR
MATSUBARA, YASUAKI, SHIMMA, NOBUO, MIWA, MASANORI, TSUJII, SHINJI, AIDA, SATOSHI, KOHCHI, YASUNORI, KOHCHI, MASAMI, MIZUGUCHI, EISAKU, ISSHIKI, YOSHIAKI, IIKURA, HITOSHI, MURATA, TAKESHI, ASO, KOSUKE
Year of Publication 02.02.2006
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Year of Publication 02.02.2006
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ORALLY ADMINISTRABLE VIRIDIOFUNGIN DERIVATIVE HAVING ANTI-HCV ACTIVITY
NAKAMA, KIMITAKA, KOHCHI, YASUNORI, KOMIYAMA, SUSUMU, WATANABE, FUMIO
Year of Publication 27.01.2016
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Year of Publication 27.01.2016
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ORALLY ADMINISTRABLE VIRIDIOFUNGIN DERIVATIVE HAVING ANTI-HCV ACTIVITY
NAKAMA, KIMITAKA, KOHCHI, YASUNORI, KOMIYAMA, SUSUMU, WATANABE, FUMIO
Year of Publication 24.06.2015
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Year of Publication 24.06.2015
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Determination of absolute stereochemistry of acyclic 1,3-polyols by a difference CD method
Mori, Yuji, Kohchi, Yasunori, Suzuki, Makoto, Furukawa, Hiroshi
Published in Journal of the American Chemical Society (01.04.1992)
Published in Journal of the American Chemical Society (01.04.1992)
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Determination of absolute stereochemistry of acyclic 1,3-polyols by a difference CD method. [Erratum to document cited in CA116(19):193389d]
Mori, Yuji, Kohchi, Yasunori, Suzuki, Makoto, Furukawa, Hiroshi
Published in Journal of the American Chemical Society (01.11.1992)
Published in Journal of the American Chemical Society (01.11.1992)
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Process for production of 2,3,4-trifluoro-5-(iodo or bromo)-benzoic acid
Koyano, Hiroshi, Iikura, Hitoshi, Isshiki, Yoshiaki, Kohchi, Yasunori
Year of Publication 20.09.2011
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Year of Publication 20.09.2011
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