Different Effects of L/N-Type and L-Type Calcium Channel Blockers on the Renin-Angiotensin-Aldosterone System in SHR/Izm
Konda, Tomoyuki, Enomoto, Azusa, Aritomi, Shizuka, Niinuma, Kazumi, Koganei, Hajime, Ogawa, Tetsuya, Nitta, Kosaku
Published in American journal of nephrology (01.01.2009)
Published in American journal of nephrology (01.01.2009)
Get full text
Journal Article
Discovery and evaluation of selective N-type calcium channel blockers: 6-Unsubstituted-1,4-dihydropyridine-5-carboxylic acid derivatives
Yamamoto, Takashi, Niwa, Seiji, Tokumasu, Munetaka, Onishi, Tomoyuki, Ohno, Seiji, Hagihara, Masako, Koganei, Hajime, Fujita, Shin-ichi, Takeda, Tomoko, Saitou, Yuki, Iwayama, Satoshi, Takahara, Akira, Iwata, Seinosuke, Shoji, Masataka
Published in Bioorganic & medicinal chemistry letters (01.06.2012)
Published in Bioorganic & medicinal chemistry letters (01.06.2012)
Get full text
Journal Article
Asymmetric synthesis and biological evaluations of (+)- and (−)-6-dimethoxymethyl-1,4-dihydropyridine-3-carboxylic acid derivatives blocking N-type calcium channels
Yamamoto, Takashi, Ohno, Seiji, Niwa, Seiji, Tokumasu, Munetaka, Hagihara, Masako, Koganei, Hajime, Fujita, Shin-ichi, Takeda, Tomoko, Saitou, Yuki, Iwayama, Satoshi, Takahara, Akira, Iwata, Seinosuke, Shoji, Masataka
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Get full text
Journal Article
The N-type and L-type calcium channel blocker cilnidipine suppresses renal injury in Dahl rats fed a high-salt diet
Aritomi, Shizuka, Koganei, Hajime, Wagatsuma, Hirotaka, Mitsui, Akira, Ogawa, Tetsuya, Nitta, Kosaku, Konda, Tomoyuki
Published in Heart and vessels (01.11.2010)
Published in Heart and vessels (01.11.2010)
Get full text
Journal Article
The structure–activity relationship study on 2-, 5-, and 6-position of the water soluble 1,4-dihydropyridine derivatives blocking N-type calcium channels
Yamamoto, Takashi, Niwa, Seiji, Ohno, Seiji, Tokumasu, Munetaka, Masuzawa, Yoko, Nakanishi, Chika, Nakajo, Akira, Onishi, Tomoyuki, Koganei, Hajime, Fujita, Shin-ichi, Takeda, Tomoko, Kito, Morikazu, Ono, Yukitsugu, Saitou, Yuki, Takahara, Akira, Iwata, Seinosuke, Shoji, Masataka
Published in Bioorganic & medicinal chemistry (01.09.2008)
Published in Bioorganic & medicinal chemistry (01.09.2008)
Get full text
Journal Article
Structure–activity relationship study of 1,4-dihydropyridine derivatives blocking N-type calcium channels
Yamamoto, Takashi, Niwa, Seiji, Ohno, Seiji, Onishi, Tomoyuki, Matsueda, Hiroyuki, Koganei, Hajime, Uneyama, Hisayuki, Fujita, Shin-ichi, Takeda, Tomoko, Kito, Morikazu, Ono, Yukitsugu, Saitou, Yuki, Takahara, Akira, Iwata, Seinosuke, Shoji, Masataka
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Get full text
Journal Article
Discovery, structure–activity relationship study, and oral analgesic efficacy of cyproheptadine derivatives possessing N-type calcium channel inhibitory activity
Yamamoto, Takashi, Niwa, Seiji, Iwayama, Satoshi, Koganei, Hajime, Fujita, Shin-ichi, Takeda, Tomoko, Kito, Morikazu, Ono, Yukitsugu, Saitou, Yuki, Takahara, Akira, Iwata, Seinosuke, Yamamoto, Hiroshi, Shoji, Masataka
Published in Bioorganic & medicinal chemistry (01.08.2006)
Published in Bioorganic & medicinal chemistry (01.08.2006)
Get full text
Journal Article
Neuronal Ca2+ Channel Blocking Action of an Antihypertensive Drug, Cilnidipine, in IMR-32 Human Neuroblastoma Cells
TAKAHARA, Akira, FUJITA, Shin-ichi, MOKI, Keiko, ONO, Yukitsugu, KOGANEI, Hajime, IWAYAMA, Satoshi, YAMAMOTO, Hiroshi
Published in Hypertension Research (2003)
Published in Hypertension Research (2003)
Get full text
Journal Article
Antithrombotic activity of AT-1015, a potent 5-HT2A receptor antagonist, in rat arterial thrombosis model and its effect on bleeding time
KIHARA, Hideaki, KOGANEI, Hajime, HIROSE, Ken, YAMAMOTO, Hiroshi, YOSHIMOTO, Ryota
Published in European journal of pharmacology (21.12.2001)
Published in European journal of pharmacology (21.12.2001)
Get full text
Journal Article
Isolation and Characterization of Aminopeptidase (Jc-peptidase) from Japanese Cedar Pollen (Cryptomeria japonica)
Noguchi, Yukinori, Nagata, Hiroyuki, Koganei, Hajime, Kodera, Yoh, Hiroto, Misao, Nishimura, Hiroyuki, Inada, Yuji, Matsushima, Ayako
Published in Journal of agricultural and food chemistry (05.06.2002)
Published in Journal of agricultural and food chemistry (05.06.2002)
Get full text
Journal Article
AT-1015, a novel serotonin (5-HT)2 receptor antagonist, blocks vascular and platelet 5-HT2A receptors and prevents the laurate-induced peripheral vascular lesion in rats
Kihara, H, Hirose, K, Koganei, H, Sasaki, N, Yamamoto, H, Kimura, A, Nishimori, T, Shoji, M, Yoshimoto, R
Published in Journal of cardiovascular pharmacology (01.04.2000)
Published in Journal of cardiovascular pharmacology (01.04.2000)
Get more information
Journal Article
Effect of AT-1015, a novel serotonin (5-HT)2 receptor antagonist, on laurate induced peripheral vascular disease model in rats
Kihara, Hideaki, Sasaki, Noriko, Hirose, Ken, Koganei, Hajime, Yamamoto, Hiroshi, Shoji, Masataka, Yoshimoto, Ryota
Published in Japanese Journal of Pharmacology (1998)
Published in Japanese Journal of Pharmacology (1998)
Get full text
Journal Article
Antithrombotic activity of AT-1015, a potent 5-HT 2A receptor antagonist, in rat arterial thrombosis model and its effect on bleeding time
Kihara, Hideaki, Koganei, Hajime, Hirose, Ken, Yamamoto, Hiroshi, Yoshimoto, Ryota
Published in European journal of pharmacology (2001)
Published in European journal of pharmacology (2001)
Get full text
Journal Article