INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors
Li, Qing, Jiang, Baishan, Guo, Jiaye, Shao, Hong, Del Priore, Isabella S, Chang, Qing, Kudo, Rei, Li, Zhiqiang, Razavi, Pedram, Liu, Bo, Boghossian, Andrew S, Rees, Matthew G, Ronan, Melissa M, Roth, Jennifer A, Donovan, Katherine A, Palafox, Marta, Reis-Filho, Jorge S, de Stanchina, Elisa, Fischer, Eric S, Rosen, Neal, Serra, Violeta, Koff, Andrew, Chodera, John D, Gray, Nathanael S, Chandarlapaty, Sarat
Published in Cancer discovery (01.02.2022)
Published in Cancer discovery (01.02.2022)
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Journal Article
ATRX is a regulator of therapy induced senescence in human cells
Kovatcheva, Marta, Liao, Will, Klein, Mary E, Robine, Nicolas, Geiger, Heather, Crago, Aimee M, Dickson, Mark A, Tap, William D, Singer, Samuel, Koff, Andrew
Published in Nature communications (30.08.2017)
Published in Nature communications (30.08.2017)
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Journal Article
Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma
D'Angelo, Sandra P, Richards, Allison L, Conley, Anthony P, Woo, Hyung Jun, Dickson, Mark A, Gounder, Mrinal, Kelly, Ciara, Keohan, Mary Louise, Movva, Sujana, Thornton, Katherine, Rosenbaum, Evan, Chi, Ping, Nacev, Benjamin, Chan, Jason E, Slotkin, Emily K, Kiesler, Hannah, Adamson, Travis, Ling, Lilan, Rao, Pavitra, Patel, Shreyaskumar, Livingston, Jonathan A, Singer, Samuel, Agaram, Narasimhan P, Antonescu, Cristina R, Koff, Andrew, Erinjeri, Joseph P, Hwang, Sinchun, Qin, Li-Xuan, Donoghue, Mark T A, Tap, William D
Published in Nature communications (16.06.2022)
Published in Nature communications (16.06.2022)
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Journal Article
A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma
Langthaler, Sonja, Rienmüller, Theresa, Scheruebel, Susanne, Pelzmann, Brigitte, Shrestha, Niroj, Zorn-Pauly, Klaus, Schreibmayer, Wolfgang, Koff, Andrew, Baumgartner, Christian
Published in PLoS computational biology (01.06.2021)
Published in PLoS computational biology (01.06.2021)
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Journal Article
PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence
Klein, Mary E, Dickson, Mark A, Antonescu, Cristina, Qin, Li-Xuan, Dooley, Scott J, Barlas, Afsar, Manova, Katia, Schwartz, Gary K, Crago, Aimee M, Singer, Samuel, Koff, Andrew, Tap, William D
Published in Oncogene (01.09.2018)
Published in Oncogene (01.09.2018)
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Journal Article
MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition
Kovatcheva, Marta, Liu, David D, Dickson, Mark A, Klein, Mary E, O'Connor, Rachael, Wilder, Fatima O, Socci, Nicholas D, Tap, William D, Schwartz, Gary K, Singer, Samuel, Crago, Aimee M, Koff, Andrew
Published in Oncotarget (10.04.2015)
Published in Oncotarget (10.04.2015)
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Journal Article
Cell-cycle inhibitors: three families united by a common cause
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Book Review
Journal Article
Phase 2 study of the CDK4 inhibitor abemaciclib in dedifferentiated liposarcoma
Dickson, Mark Andrew, Koff, Andrew, D'Angelo, Sandra P., Gounder, Mrinal M., Keohan, Mary Louise, Kelly, Ciara Marie, Chi, Ping, Antonescu, Cristina R., Landa, Jonathan, Qin, Li-Xuan, Crago, Aimee Marie, Singer, Samuel, Tap, William D.
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
Hdm2- and proteasome-dependent turnover limits p21 accumulation during S phase
Ciznadija, Daniel, Zhu, Xin-Hua, Koff, Andrew
Published in Cell cycle (Georgetown, Tex.) (15.08.2011)
Published in Cell cycle (Georgetown, Tex.) (15.08.2011)
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Journal Article
Interweaving the Cell Cycle Machinery with Cell Differentiation
Miller, Jeffrey P., Yeh, Nancy, Vidal, Anxo, Koff, Andrew
Published in Cell cycle (Georgetown, Tex.) (01.12.2007)
Published in Cell cycle (Georgetown, Tex.) (01.12.2007)
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Journal Article
The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior
Liu, Yan, Elf, Shannon E., Asai, Takashi, Miyata, Yasuhiko, Liu, Yuhui, Sashida, Goro, Huang, Gang, Di Giandomenico, Silvana, Koff, Andrew, Nimer, Stephen D.
Published in Cell cycle (Georgetown, Tex.) (01.10.2009)
Published in Cell cycle (Georgetown, Tex.) (01.10.2009)
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Journal Article
ZIC1 Overexpression Is Oncogenic in Liposarcoma
BRILL, Elliott, GOBBLE, Ryan, TAYLOR, Barry S, SANDER, Chris, KOFF, Andrew, SINGER, Samuel, ANGELES, Christina, LAGOS-QUINTANA, Mariana, CRAGO, Aimee, LAXA, Bernadette, DECAROLIS, Penelope, LEI ZHANG, ANTONESCU, Cristina, SOCCI, Nicholas D
Published in Cancer research (Chicago, Ill.) (01.09.2010)
Published in Cancer research (Chicago, Ill.) (01.09.2010)
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Journal Article
Misexpression of Cyclin B3 Leads to Aberrant Spermatogenesis
Refik-Rogers, Jale, Manova, Katia, Koff, Andrew
Published in Cell cycle (Georgetown, Tex.) (01.09.2006)
Published in Cell cycle (Georgetown, Tex.) (01.09.2006)
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Journal Article
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1)
Kiyokawa, H, Kineman, R D, Manova-Todorova, K O, Soares, V C, Hoffman, E S, Ono, M, Khanam, D, Hayday, A C, Frohman, L A, Koff, A
Published in Cell (31.05.1996)
Published in Cell (31.05.1996)
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Journal Article
A U-Rich Element in the 5′ Untranslated Region Is Necessary for the Translation of p27 mRNA
Millard, S. Sean, Vidal, Anxo, Markus, Maurice, Koff, Andrew
Published in Molecular and Cellular Biology (01.08.2000)
Published in Molecular and Cellular Biology (01.08.2000)
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Journal Article
Characterization and Expression of Mammalian Cyclin B3, a Prepachytene Meiotic Cyclin
Nguyen, T B, Manova, K, Capodieci, P, Lindon, C, Bottega, S, Wang, X, Refik-Rogers, J, Pines, J, Wolgemuth, D J, Koff, A
Published in The Journal of biological chemistry (01.11.2002)
Published in The Journal of biological chemistry (01.11.2002)
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Journal Article
Functional interaction of the retinoblastoma and Ini1/Snf5 tumor suppressors in cell growth and pituitary tumorigenesis
GUIDI, Cynthia J, MUDHASANI, Rajini, HOOVER, Kathleen, KOFF, Andrew, LEAV, Irwin, IMBALZANO, Anthony N, JONES, Stephen N
Published in Cancer research (Chicago, Ill.) (15.08.2006)
Published in Cancer research (Chicago, Ill.) (15.08.2006)
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