Design, Synthesis, and Preliminary Evaluation of Doxazolidine Carbamates as Prodrugs Activated by Carboxylesterases
Burkhart, David J, Barthel, Benjamin L, Post, Glen C, Kalet, Brian T, Nafie, Jordan W, Shoemaker, Richard K, Koch, Tad H
Published in Journal of medicinal chemistry (30.11.2006)
Published in Journal of medicinal chemistry (30.11.2006)
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Journal Article
Doxazolidine Induction of Apoptosis by a Topoisomerase II Independent Mechanism
Kalet, Brian T, McBryde, Meagan B, Espinosa, Joaquin M, Koch, Tad H
Published in Journal of medicinal chemistry (06.09.2007)
Published in Journal of medicinal chemistry (06.09.2007)
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Journal Article
Doxazolidine, a Proposed Active Metabolite of Doxorubicin That Cross-links DNA
Post, Glen C, Barthel, Benjamin L, Burkhart, David J, Hagadorn, John R, Koch, Tad H
Published in Journal of medicinal chemistry (01.12.2005)
Published in Journal of medicinal chemistry (01.12.2005)
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Journal Article
Photocross-linking of nucleic acids to associated proteins
Meisenheimer, K.M, Koch, T.H
Published in Critical reviews in biochemistry and molecular biology (01.01.1997)
Published in Critical reviews in biochemistry and molecular biology (01.01.1997)
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Journal Article
Kinetic Analysis of Site-specific Photoaptamer–Protein Cross-linking
Koch, Tad H., Smith, Drew, Tabacman, Eduardo, Zichi, Dominic A.
Published in Journal of molecular biology (05.03.2004)
Published in Journal of molecular biology (05.03.2004)
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Journal Article
Antiestrogen Binding Site and Estrogen Receptor Mediate Uptake and Distribution of 4-Hydroxytamoxifen-Targeted Doxorubicin−Formaldehyde Conjugate in Breast Cancer Cells
Burke, Patrick J, Kalet, Brian T, Koch, Tad H
Published in Journal of medicinal chemistry (16.12.2004)
Published in Journal of medicinal chemistry (16.12.2004)
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Journal Article
Coordination Chemistry of Verdazyl Radicals: Group 12 Metal (Zn, Cd, Hg) Complexes of 1,4,5,6-Tetrahydro-2,4-dimethyl-6-(2‘-pyridyl)-1,2,4,5-tetrazin-3(2H)-one (pvdH3) and 1,5-Dimethyl-3-(2‘-pyridyl)-6-oxoverdazyl (pvd)
Brook, David J. R., Fornell, Spring, Stevens, Jonathan E., Noll, Bruce, Koch, Tad H., Eisfeld, Wolfgang
Published in Inorganic chemistry (07.02.2000)
Published in Inorganic chemistry (07.02.2000)
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Journal Article
Doxoform and Daunoform: Anthracycline−Formaldehyde Conjugates Toxic to Resistant Tumor Cells
Fenick, David J, Taatjes, Dylan J, Koch, Tad H
Published in Journal of medicinal chemistry (01.08.1997)
Published in Journal of medicinal chemistry (01.08.1997)
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Journal Article
Alkylation of DNA by the Anthracycline, Antitumor Drugs Adriamycin and Daunomycin
Taatjes, Dylan J, Gaudiano, Giorgio, Resing, Katheryn, Koch, Tad H
Published in Journal of medicinal chemistry (11.10.1996)
Published in Journal of medicinal chemistry (11.10.1996)
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Journal Article
Lack of glutathione conjugation to adriamycin in human breast cancer MCF-7/DOX cells: Inhibition of glutathione s-transferase p1–1 by glutathione conjugates from anthracyclines
Gaudiano, Giorgio, Koch, Tad H, Lo Bello, Mario, Nuccetelli, Marzia, Ravagnan, Giampietro, Serafino, Annalucia, Sinibaldi-Vallebona, Paola
Published in Biochemical pharmacology (15.12.2000)
Published in Biochemical pharmacology (15.12.2000)
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Journal Article
Telomeric Protein-DNA Point Contracts Identified by Photo-Crosslinking Using 5-Bromodeoxyuridine
Hicke, Brian J, Willis, Michael C, Koch, Tad H, Cech, Thomas R
Published in Biochemistry (Easton) (22.03.1994)
Published in Biochemistry (Easton) (22.03.1994)
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Journal Article
Mass Spectrometric Measurement of Formaldehyde Generated in Breast Cancer Cells upon Treatment with Anthracycline Antitumor Drugs
Kato, Shuji, Burke, Patrick J, Fenick, David J, Taatjes, Dylan J, Bierbaum, Veronica M, Koch, Tad H
Published in Chemical research in toxicology (01.06.2000)
Published in Chemical research in toxicology (01.06.2000)
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Journal Article
Doxorubicin-formaldehyde conjugates targeting αvβ3 integrin
Burkhart, David J., Kalet, Brian T., Coleman, Michael P., Post, Glen C., Koch, Tad H.
Published in Molecular cancer therapeutics (01.12.2004)
Published in Molecular cancer therapeutics (01.12.2004)
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