Aptamer-based multiplexed proteomic technology for biomarker discovery
Gold, Larry, Ayers, Deborah, Bertino, Jennifer, Bock, Christopher, Bock, Ashley, Brody, Edward N, Carter, Jeff, Dalby, Andrew B, Eaton, Bruce E, Fitzwater, Tim, Flather, Dylan, Forbes, Ashley, Foreman, Trudi, Fowler, Cate, Gawande, Bharat, Goss, Meredith, Gunn, Magda, Gupta, Shashi, Halladay, Dennis, Heil, Jim, Heilig, Joe, Hicke, Brian, Husar, Gregory, Janjic, Nebojsa, Jarvis, Thale, Jennings, Susan, Katilius, Evaldas, Keeney, Tracy R, Kim, Nancy, Koch, Tad H, Kraemer, Stephan, Kroiss, Luke, Le, Ngan, Levine, Daniel, Lindsey, Wes, Lollo, Bridget, Mayfield, Wes, Mehan, Mike, Mehler, Robert, Nelson, Sally K, Nelson, Michele, Nieuwlandt, Dan, Nikrad, Malti, Ochsner, Urs, Ostroff, Rachel M, Otis, Matt, Parker, Thomas, Pietrasiewicz, Steve, Resnicow, Daniel I, Rohloff, John, Sanders, Glenn, Sattin, Sarah, Schneider, Daniel, Singer, Britta, Stanton, Martin, Sterkel, Alana, Stewart, Alex, Stratford, Suzanne, Vaught, Jonathan D, Vrkljan, Mike, Walker, Jeffrey J, Watrobka, Mike, Waugh, Sheela, Weiss, Allison, Wilcox, Sheri K, Wolfson, Alexey, Wolk, Steven K, Zhang, Chi, Zichi, Dom
Published in PloS one (07.12.2010)
Published in PloS one (07.12.2010)
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Journal Article
DNA repair in response to anthracycline-DNA adducts: a role for both homologous recombination and nucleotide excision repair
Spencer, Damian M S, Bilardi, Rebecca A, Koch, Tad H, Post, Glen C, Nafie, Jordan W, Kimura, Ken-Ichi, Cutts, Suzanne M, Phillips, Don R
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (01.02.2008)
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (01.02.2008)
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Journal Article
Preclinical Efficacy of a Carboxylesterase 2-Activated Prodrug of Doxazolidine
Barthel, Benjamin L, Zhang, Zhiyong, Rudnicki, Daniel L, Coldren, Christopher D, Polinkovsky, Margaret, Sun, Hengrui, Koch, Gary G, Chan, Daniel C. F, Koch, Tad H
Published in Journal of medicinal chemistry (10.12.2009)
Published in Journal of medicinal chemistry (10.12.2009)
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Journal Article
Identification of Human Intestinal Carboxylesterase as the Primary Enzyme for Activation of a Doxazolidine Carbamate Prodrug
Barthel, Benjamin L, Torres, Renee C, Hyatt, Janice L, Edwards, Carol C, Hatfield, M. Jason, Potter, Philip M, Koch, Tad H
Published in Journal of medicinal chemistry (24.01.2008)
Published in Journal of medicinal chemistry (24.01.2008)
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Journal Article
Sensitivity and Specificity of Photoaptamer Probes
Smith, Drew, Collins, Brian D, Heil, James, Koch, Tad H
Published in Molecular & cellular proteomics (01.01.2003)
Published in Molecular & cellular proteomics (01.01.2003)
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Journal Article
Photoactivatable Prodrug of Doxazolidine Targeting Exosomes
Tamura, Ryo, Balabanova, Alla, Frakes, Samuel A, Bargmann, Austin, Grimm, Jan, Koch, Tad H, Yin, Hang
Published in Journal of medicinal chemistry (28.02.2019)
Published in Journal of medicinal chemistry (28.02.2019)
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Journal Article
Diagnostic potential of photoSELEX-evolved ssDNA aptamers
GOLDEN, Mace C, COLLINS, Brian D, WILLIS, Michael C, KOCH, Tad H
Published in Journal of biotechnology (25.08.2000)
Published in Journal of biotechnology (25.08.2000)
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Journal Article
Colloidal Drug Aggregate Stability in High Serum Conditions and Pharmacokinetic Consequence
Ganesh, Ahil N, Aman, Ahmed, Logie, Jennifer, Barthel, Ben L, Cogan, Peter, Al-awar, Rima, Koch, Tad H, Shoichet, Brian K, Shoichet, Molly S
Published in ACS chemical biology (19.04.2019)
Published in ACS chemical biology (19.04.2019)
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Journal Article
Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs
Xiao, Da, Shi, Deshi, Yang, Dongfang, Barthel, Benjamin, Koch, Tad H., Yan, Bingfang
Published in Biochemical pharmacology (01.02.2013)
Published in Biochemical pharmacology (01.02.2013)
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Journal Article
Correlation of in Situ Oxazolidine Formation with Highly Synergistic Cytotoxicity and DNA Cross-Linking in Cancer Cells from Combinations of Doxorubicin and Formaldehyde
Barthel, Benjamin L, Mooz, Erin L, Wiener, Laura Elizabeth, Koch, Gary G, Koch, Tad H
Published in Journal of medicinal chemistry (10.03.2016)
Published in Journal of medicinal chemistry (10.03.2016)
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Journal Article
Chemical Ionization Mass Spectrometric Determination of Acrolein in Human Breast Cancer Cells
Kato, Shuji, Post, Glen C., Bierbaum, Veronica M., Koch, Tad H.
Published in Analytical biochemistry (15.06.2002)
Published in Analytical biochemistry (15.06.2002)
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Journal Article
Using in vitro Selection to Direct the Covalent Attachment of Human Immunodeficiency Virus Type 1 Rev Protein to High-Affinity RNA Ligands
Jensen, K B, Atkinson, B L, Willis, M C, Koch, T H, Gold, L
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.1995)
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.1995)
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Journal Article
Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins
WILLIS, M. C, HICKE, B. J, UHLENBECK, O. C, CECH, T. R, KOCH, T. H
Published in Science (American Association for the Advancement of Science) (19.11.1993)
Published in Science (American Association for the Advancement of Science) (19.11.1993)
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Journal Article
Production of Formaldehyde and DNA−Adriamycin or DNA−Daunomycin Adducts, Initiated through Redox Chemistry of Dithiothreitol/Iron, Xanthine Oxidase/NADH/Iron, or Glutathione/Iron
Taatjes, Dylan J, Gaudiano, Giorgio, Koch, Tad H
Published in Chemical research in toxicology (01.09.1997)
Published in Chemical research in toxicology (01.09.1997)
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Journal Article