Search Results - "KOBERSTEIN, RALF" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Promotion of sleep by targeting the orexin system in rats, dogs and humans

Promotion of sleep by targeting the orexin system in rats, dogs and humans

by Jenck, François, Brisbare-Roch, Catherine, Dingemanse, Jasper, Koberstein, Ralf, Hoever, Petra, Aissaoui, Hamed, Flores, Susan, Mueller, Celia, Nayler, Oliver, van Gerven, Joop, de Haas, Sanne L, Hess, Patrick, Qiu, Changbin, Buchmann, Stephan, Scherz, Michael, Weller, Thomas, Fischli, Walter, Clozel, Martine
Published in Nature medicine (01.02.2007)

Get full text

Journal Article

Structure–activity relationship studies and sleep-promoting activity of novel 1-chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 2

Structure–activity relationship studies and sleep-promoting activity of novel 1-chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 2

by Sifferlen, Thierry, Koberstein, Ralf, Cottreel, Emmanuelle, Boller, Amandine, Weller, Thomas, Gatfield, John, Brisbare-Roch, Catherine, Jenck, Francois, Boss, Christoph
Published in Bioorganic & medicinal chemistry letters (01.07.2013)

Get full text

Journal Article

Synthesis, structure–activity relationship studies, and identification of novel 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 1

Synthesis, structure–activity relationship studies, and identification of novel 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 1

by Sifferlen, Thierry, Koberstein, Ralf, Cottreel, Emmanuelle, Boller, Amandine, Weller, Thomas, Gatfield, John, Brisbare-Roch, Catherine, Jenck, Francois, Boss, Christoph
Published in Bioorganic & medicinal chemistry letters (01.04.2013)

Get full text

Journal Article

Orexin Receptor Antagonism: A New Principle in Neuroscience

Orexin Receptor Antagonism: A New Principle in Neuroscience

by Christoph Boss, Catherine Brisbare-Roch, Francois Jenck, Hamed Aissaoui, Ralf Koberstein, Thierry Sifferlen, Thomas Weller
Published in Chimia (01.01.2008)

Get full text

Journal Article

Tetrahydroisoquinolines as orexin receptor antagonists: Strategies for lead optimization by solution-phase chemistry

Tetrahydroisoquinolines as orexin receptor antagonists: Strategies for lead optimization by solution-phase chemistry

by Koberstein, R, Aissaoui, H, Bur, D, Clozel, M, Fischli, W, Jenck, F, Mueller, C, Nayler, O, Sifferlen, T, Treiber, A, Weller, T
Published in Chimia (01.05.2003)

Get full text

Journal Article

N-Glycine-sulfonamides as potent dual orexin 1/orexin 2 receptor antagonists

N-Glycine-sulfonamides as potent dual orexin 1/orexin 2 receptor antagonists

by Aissaoui, Hamed, Koberstein, Ralf, Zumbrunn, Cornelia, Gatfield, John, Brisbare-Roch, Catherine, Jenck, Francois, Treiber, Alexander, Boss, Christoph
Published in Bioorganic & medicinal chemistry (01.11.2008)

Get full text

Journal Article

Novel pyrazolo-tetrahydropyridines as potent orexin receptor antagonists

Novel pyrazolo-tetrahydropyridines as potent orexin receptor antagonists

by Sifferlen, Thierry, Boss, Christoph, Cottreel, Emmanuelle, Koberstein, Ralf, Gude, Markus, Aissaoui, Hamed, Weller, Thomas, Gatfield, John, Brisbare-Roch, Catherine, Jenck, Francois
Published in Bioorganic & medicinal chemistry letters (01.03.2010)

Get full text

Journal Article

Reply to 'Promotion of sleep by targeting the orexin system in rats, dogs and humans'

Reply to 'Promotion of sleep by targeting the orexin system in rats, dogs and humans'

by Jenck, Francois, Brisbare-Roch, Catherine, Scherz, Michael, Flores, Susan, Koberstein, Ralf, Nayler, Oliver, Dingemanse, Jasper, Clozel, Martine
Published in Nature medicine (01.05.2007)

Get full text

Journal Article

5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE COMPOUNDS

5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE COMPOUNDS

by AISSAOUI HAMED, SIEGRIST ROMAIN, SIFFERLEN THIERRY, KOBERSTEIN RALF, BOSS CHRISTOPH
Year of Publication 06.04.2011

Get full text

Patent

2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES

2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES

by TRACHSEL DANIEL, AISSAOUI HAMED, SIFFERLEN THIERRY, KOBERSTEIN RALF, BOSS CHRISTOPH
Year of Publication 09.11.2010

Get full text

Patent

1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS

1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS

by GUDE MARKUS, AISSAOUI HAMED, SIFFERLEN THIERRY, KOBERSTEIN RALF, BOSS CHRISTOPH
Year of Publication 26.05.2010

Get full text

Patent

3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS

3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS

by GUDE MARKUS, AISSAOUI HAMED, SIFFERLEN THIERRY, KOBERSTEIN RALF, BOSS CHRISTOPH
Year of Publication 22.04.2010

Get full text

Patent

PIPERIDINE AND PYRROLIDINE COMPOUNDS

PIPERIDINE AND PYRROLIDINE COMPOUNDS

by TRACHSEL DANIEL, AISSAOUI HAMED, SIEGRIST ROMAIN, SIFFERLEN THIERRY, KOBERSTEIN RALF, BOSS CHRISTOPH
Year of Publication 27.12.2010

Get full text

Patent

2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES

2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES

by TRACHSEL DANIEL, GUDE MARKUS, AISSAOUI HAMED, SIFFERLEN THIERRY, KOBERSTEIN RALF, BOSS CHRISTOPH
Year of Publication 04.05.2010

Get full text

Patent

PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES

PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES

by TRACHSEL DANIEL, AISSAOUI HAMED, SIEGRIST ROMAIN, SIFFERLEN THIERRY, WILLIAMS JODI T, KOBERSTEIN RALF, BOSS CHRISTOPH, BROTSCHI CHRISTINE
Year of Publication 27.06.2011

Get full text

Patent

TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS

TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS

by AISSAOUI HAMED, GATFIELD JOHN, SIEGRIST ROMAIN, SIFFERLEN THIERRY, WILLIAMS JODI T, KOBERSTEIN RALF, BOSS CHRISTOPH, BROTSCHI CHRISTINE
Year of Publication 03.03.2011

Get full text

Patent

2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

by TRACHSEL DANIEL, GUDE MARKUS, AISSAOUI HAMED, SIFFERLEN THIERRY, KOBERSTEIN RALF, BOSS CHRISTOPH
Year of Publication 03.09.2009

Get full text

Patent

TRISUBSTITUTED 3,4-DIHYDRO-1H-ISOQUINOLIN COMPOUND, PROCESS FOR ITS PREPARATION, AND ITS USE

TRISUBSTITUTED 3,4-DIHYDRO-1H-ISOQUINOLIN COMPOUND, PROCESS FOR ITS PREPARATION, AND ITS USE

by NAZIR ZARGHUN, DOMIN DORIS, DE VRIES ANDREAS HENDRIKUS MARIA, VERZIJL GERARDUS KAREL MARIA, IMBODEN CHRISTOPH, SKRANC WOLFGANG, KOBERSTEIN RALF, STANEK MICHAEL, HELMS MATTHIAS, TSCHEBULL WILHELM
Year of Publication 12.10.2010

Get full text

Patent

The stereochemistry of a retro-carbolithiation reaction

The stereochemistry of a retro-carbolithiation reaction

by Hoffmann, RW, Koberstein, R
Published in Chemical communications (Cambridge, England) (07.01.1999)

Get full text

Journal Article

Pressure medium cylinder e.g. hydraulic master cylinder, for e.g. hydraulic braking system, to actuate friction coupling of motor vehicle, has guide sleeve axially supported at housing and at safety element firmly connected with housing

Pressure medium cylinder e.g. hydraulic master cylinder, for e.g. hydraulic braking system, to actuate friction coupling of motor vehicle, has guide sleeve axially supported at housing and at safety element firmly connected with housing

by KOBERSTEIN, RALF
Year of Publication 27.05.2010

Get full text

Patent

1
2
3
4
5
6
7
8
9
10
11
Next
[20]