CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant
Sakamoto, Hiroshi, Tsukaguchi, Toshiyuki, Hiroshima, Sayuri, Kodama, Tatsushi, Kobayashi, Takamitsu, Fukami, Takaaki A., Oikawa, Nobuhiro, Tsukuda, Takuo, Ishii, Nobuya, Aoki, Yuko
Published in Cancer cell (17.05.2011)
Published in Cancer cell (17.05.2011)
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Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice
Suzuki, Masayuki, Honda, Kiyofumi, Fukazawa, Masanori, Ozawa, Kazuharu, Hagita, Hitoshi, Kawai, Takahiro, Takeda, Minako, Yata, Tatsuo, Kawai, Mio, Fukuzawa, Taku, Kobayashi, Takamitsu, Sato, Tsutomu, Kawabe, Yoshiki, Ikeda, Sachiya
Published in The Journal of pharmacology and experimental therapeutics (01.06.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2012)
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Design and synthesis of a highly selective, orally active and potent anaplastic lymphoma kinase inhibitor (CH5424802)
Kinoshita, Kazutomo, Asoh, Kohsuke, Furuichi, Noriyuki, Ito, Toshiya, Kawada, Hatsuo, Hara, Sousuke, Ohwada, Jun, Miyagi, Takuho, Kobayashi, Takamitsu, Takanashi, Kenji, Tsukaguchi, Toshiyuki, Sakamoto, Hiroshi, Tsukuda, Takuo, Oikawa, Nobuhiro
Published in Bioorganic & medicinal chemistry (01.02.2012)
Published in Bioorganic & medicinal chemistry (01.02.2012)
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Discovery of Tofogliflozin, a Novel C‑Arylglucoside with an O‑Spiroketal Ring System, as a Highly Selective Sodium Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes
Ohtake, Yoshihito, Sato, Tsutomu, Kobayashi, Takamitsu, Nishimoto, Masahiro, Taka, Naoki, Takano, Koji, Yamamoto, Keisuke, Ohmori, Masayuki, Yamaguchi, Marina, Takami, Kyoko, Yeu, Sang-Yong, Ahn, Koo-Hyeon, Matsuoka, Hiroharu, Morikawa, Kazumi, Suzuki, Masayuki, Hagita, Hitoshi, Ozawa, Kazuharu, Yamaguchi, Koji, Kato, Motohiro, Ikeda, Sachiya
Published in Journal of medicinal chemistry (13.09.2012)
Published in Journal of medicinal chemistry (13.09.2012)
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