Mutational Replacement of Leu-293 in the Class C Enterobacter cloacae P99 β-Lactamase Confers Increased MIC of Cefepime
VAKULENKO, Sergei B, GOLEMI, Dasantila, GERYK, Bruce, SUVOROV, Maxim, KNOX, James R, MOBASHERY, Shahriar, LERNER, Stephen A
Published in Antimicrobial Agents and Chemotherapy (01.06.2002)
Published in Antimicrobial Agents and Chemotherapy (01.06.2002)
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Enzymes of vancomycin resistance: the structure of d-alanine– d-lactate ligase of naturally resistant Leuconostoc mesenteroides
Kuzin, Alexandre P, Sun, Tao, Jorczak-Baillass, Jodi, Healy, Vicki L, Walsh, Christopher T, Knox, James R
Published in Structure (London) (15.05.2000)
Published in Structure (London) (15.05.2000)
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Crystallographic Structure of a Phosphonate Derivative of the Enterobacter cloacae P99 Cephalosporinase: Mechanistic Interpretation of a .beta.-Lactamase Transition-State Analog
Lobkovsky, Emil, Billings, Eric M, Moews, Paul C, Rahil, Jubrail, Pratt, R. F, Knox, James R
Published in Biochemistry (Easton) (07.06.1994)
Published in Biochemistry (Easton) (07.06.1994)
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Inhibition of Class A β-Lactamases by Carbapenems: Crystallographic Observation of Two Conformations of Meropenem in SHV-1
Nukaga, Michiyosi, Bethel, Christopher R, Thomson, Jodi M, Hujer, Andrea M, Distler, Anne, Anderson, Vernon E, Knox, James R, Bonomo, Robert A
Published in Journal of the American Chemical Society (24.09.2008)
Published in Journal of the American Chemical Society (24.09.2008)
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Binding of cephalothin and cefotaxime to D-Ala-D-Ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum .beta.-lactamases
Kuzin, Alexandre P, Liu, Hansong, Kelly, Judith A, Knox, James R
Published in Biochemistry (Easton) (25.07.1995)
Published in Biochemistry (Easton) (25.07.1995)
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Ultrahigh Resolution Structure of a Class A β-Lactamase: On the Mechanism and Specificity of the Extended-spectrum SHV-2 Enzyme
Nukaga, Michiyoshi, Mayama, Kayoko, Hujer, Andrea M., Bonomo, Robert A., Knox, James R.
Published in Journal of molecular biology (18.04.2003)
Published in Journal of molecular biology (18.04.2003)
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Structure−Activity Relationship of 6-Methylidene Penems Bearing Tricyclic Heterocycles as Broad-Spectrum β-Lactamase Inhibitors: Crystallographic Structures Show Unexpected Binding of 1,4-Thiazepine Intermediates
Venkatesan, Aranapakam M, Gu, Yansong, Santos, Osvaldo Dos, Abe, Takao, Agarwal, Atul, Yang, Youjun, Petersen, Peter J, Weiss, William J, Mansour, Tarek S, Nukaga, Michiyoshi, Hujer, Andrea M, Bonomo, Robert A, Knox, James R
Published in Journal of medicinal chemistry (16.12.2004)
Published in Journal of medicinal chemistry (16.12.2004)
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Structure-Function Studies of Ser-289 in the Class C β-Lactamase from Enterobacter cloacae P99
TREPANIER, S, KNOX, J. R, CLAIROUX, N, SANSCHAGRIN, F, LEVESQUE, R. C, HULETSKY, A
Published in Antimicrobial Agents and Chemotherapy (01.03.1999)
Published in Antimicrobial Agents and Chemotherapy (01.03.1999)
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Structure-Activity Relationship of 6-Methylidene Penems Bearing 6,5 Bicyclic Heterocycles as Broad-Spectrum β-Lactamase Inhibitors: Evidence for 1,4-Thiazepine Intermediates with C7 R Stereochemistry by Computational Methods
Venkatesan, Aranapakam M, Agarwal, Atul, Abe, Takao, Ushirogochi, Hideki, Yamamura, Itsuka, Ado, Mihira, Tsuyoshi, Takasaki, Dos Santos, Osvaldo, Gu, Yansong, Sum, Fuk-Wah, Li, Zhong, Francisco, Gerry, Lin, Yang-I, Petersen, Peter J, Yang, Youjun, Kumagai, Toshio, Weiss, William J, Shlaes, David M, Knox, James R, Mansour, Tarek S
Published in Journal of medicinal chemistry (27.07.2006)
Published in Journal of medicinal chemistry (27.07.2006)
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Inhibition of Class A and Class C β-Lactamases by Penems: Crystallographic Structures of a Novel 1,4-Thiazepine Intermediate
Nukaga, Michiyoshi, Abe, Takao, Venkatesan, Aranapakam M, Mansour, Tarek S, Bonomo, Robert A, Knox, James R
Published in Biochemistry (Easton) (18.11.2003)
Published in Biochemistry (Easton) (18.11.2003)
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Inhibition of the SHV-1 β-Lactamase by Sulfones: Crystallographic Observation of Two Reaction Intermediates with Tazobactam
Kuzin, Alexandre P, Nukaga, Michiyoshi, Nukaga, Yasuko, Hujer, Andrea, Bonomo, Robert A, Knox, James R
Published in Biochemistry (Easton) (13.02.2001)
Published in Biochemistry (Easton) (13.02.2001)
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Structure of the SHV-1 β-Lactamase
Kuzin, Alexandre P, Nukaga, Michiyoshi, Nukaga, Yasuko, Hujer, Andrea M, Bonomo, Robert A, Knox, James R
Published in Biochemistry (Easton) (04.05.1999)
Published in Biochemistry (Easton) (04.05.1999)
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Structure of the Extended-Spectrum Class C β-Lactamase of Enterobacter cloacae GC1, a Natural Mutant with a Tandem Tripeptide Insertion
Crichlow, Gregg V, Kuzin, Alexandre P, Nukaga, Michiyoshi, Mayama, Kayoko, Sawai, Tetsuo, Knox, James R
Published in Biochemistry (Easton) (10.08.1999)
Published in Biochemistry (Easton) (10.08.1999)
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d-Alanine:d-Alanine Ligase: Phosphonate and Phosphinate Intermediates with Wild Type and the Y216F Mutant
Fan, Chang, Park, Il-Seon, Walsh, Christopher T, Knox, James R
Published in Biochemistry (Easton) (04.03.1997)
Published in Biochemistry (Easton) (04.03.1997)
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Structure of an extended-spectrum class A β-lactamase from Proteus vulgaris K1
Nukaga, Michiyoshi, Mayama, Kayoko, Crichlow, Gregg V, Knox, James R
Published in Journal of molecular biology (15.03.2002)
Published in Journal of molecular biology (15.03.2002)
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