Reduction of mitomycin C is catalysed by human recombinant NRH:quinone oxidoreductase 2 using reduced nicotinamide adenine dinucleotide as an electron donating co-factor
JAMIESON, D, TUNG, A. T. Y, KNOX, R. J, BODDY, A. V
Published in British journal of cancer (06.11.2006)
Published in British journal of cancer (06.11.2006)
Get full text
Journal Article
Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2 : A novel co-substrate-mediated antitumor prodrug therapy
KNOX, R. J, JENKINS, T. C, HOBBS, S. M, SHIUAN CHEN, MELTON, R. G, BURKE, P. J
Published in Cancer research (Chicago, Ill.) (01.08.2000)
Get full text
Published in Cancer research (Chicago, Ill.) (01.08.2000)
Journal Article
A thallium-sensitive, fluorescence-based assay for detecting and characterizing potassium channel modulators in mammalian cells
Weaver, C David, Harden, David, Dworetzky, Steven I, Robertson, Barbara, Knox, Ronald J
Published in Journal of biomolecular screening (01.12.2004)
Published in Journal of biomolecular screening (01.12.2004)
Get full text
Journal Article
Evolution of an Enzyme Activity: Crystallographic Structure at 2- Å Resolution of Cephalosporinase from the ampC Gene of Enterobacter cloacae P99 and Comparison with a Class A Penicillinase
Lobkovsky, Emil, Moews, Paul C., Liu, Hansong, Zhao, Haiching, Frere, Jean-Marie, Knox, James R.
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.1993)
Get full text
Journal Article
Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954
Bridgewater, J.A., Springer, C.J., Knox, R.J., Minton, N.P., Michael, N.P., Collins, M.K.
Published in European journal of cancer (1990) (01.12.1995)
Published in European journal of cancer (1990) (01.12.1995)
Get full text
Journal Article
Criterion-related validity of the cultural web when assessing safety culture
Cooper, M.D., Collins, M., Bernard, R., Schwann, S., Knox, R.J.
Published in Safety science (01.01.2019)
Published in Safety science (01.01.2019)
Get full text
Journal Article
Regulation of insulin of a unique neuronal Ca2+ pool and of neuropeptide secretion
JONAS, E. A, KNOX, R. J, SMITH, T. C. M, WAYNE, N. L, CONNOR, J. A, KACZMAREK, L. K
Published in Nature (London) (23.01.1997)
Published in Nature (London) (23.01.1997)
Get full text
Journal Article
Beta-lactamase of Bacillus licheniformis 749/C at 2 A resolution
Moews, P C, Knox, J R, Dideberg, O, Charlier, P, Frère, J M
Published in Proteins, structure, function, and bioinformatics (1990)
Published in Proteins, structure, function, and bioinformatics (1990)
Get more information
Journal Article
Bioactivation of dinitrobenzamide mustards by an E. coli B nitroreductase
Anlezark, G.M., Melton, R.G., Sherwood, R.F., Wilson, W.R., Denny, W.A., Palmer, B.D., Knox, R.J., Friedlos, F., Williams, A.
Published in Biochemical pharmacology (25.08.1995)
Published in Biochemical pharmacology (25.08.1995)
Get full text
Journal Article
Brain‐Derived Neurotrophic Factor Induces Excitotoxic Sensitivity in Cultured Embryonic Rat Spinal Motor Neurons Through Activation of the Phosphatidylinositol 3‐Kinase Pathway
Fryer, Hugh J. L., Wolf, Daniel H., Knox, Ronald J., Strittmatter, Stephen M., Pennica, Diane, O'Leary, Rhona M., Russell, David S., Kalb, Robert G.
Published in Journal of neurochemistry (01.02.2000)
Published in Journal of neurochemistry (01.02.2000)
Get full text
Journal Article
Role of Ser-238 and Lys-240 in the hydrolysis of third-generation cephalosporins by SHV-type beta-lactamases probed by site-directed mutagenesis and three-dimensional modeling
HULETSKY, A, KNOX, J. R, LEVESQUE, R. C
Published in The Journal of biological chemistry (15.02.1993)
Published in The Journal of biological chemistry (15.02.1993)
Get full text
Journal Article
Excitotoxic Death of a Subset of Embryonic Rat Motor Neurons In Vitro
Fryer, Hugh J. L., Knox, Ronald J., Strittmatter, Stephen M., Kalb, Robert
Published in Journal of neurochemistry (01.02.1999)
Published in Journal of neurochemistry (01.02.1999)
Get full text
Journal Article
Insulin receptor in Aplysia neurons: characterization, molecular cloning, and modulation of ion currents
Jonas, EA, Knox, RJ, Kaczmarek, LK, Schwartz, JH, Solomon, DH
Published in The Journal of neuroscience (01.03.1996)
Published in The Journal of neuroscience (01.03.1996)
Get full text
Journal Article
Characterization of a new TEM-derived beta-lactamase produced in a Serratia marcescens strain
PERILLI, M, FELICI, A, FRANCESCHINI, N, DE SANTIS, A, PAGANI, L, LUZZARO, F, ORATORE, A, ROSSOLINI, G. M, KNOX, J. R, AMICOSANTE, G
Published in Antimicrobial Agents and Chemotherapy (01.11.1997)
Published in Antimicrobial Agents and Chemotherapy (01.11.1997)
Get full text
Journal Article
Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum (II) and cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA
KNOX, R. J, FRIEDLOS, F, LYDALL, D. A, ROBERTS, J. J
Published in Cancer research (Chicago, Ill.) (01.04.1986)
Get full text
Published in Cancer research (Chicago, Ill.) (01.04.1986)
Journal Article