Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer
Uhlitz, Florian, Bischoff, Philip, Peidli, Stefan, Sieber, Anja, Trinks, Alexandra, Lüthen, Mareen, Obermayer, Benedikt, Blanc, Eric, Ruchiy, Yana, Sell, Thomas, Mamlouk, Soulafa, Arsie, Roberto, Wei, Tzu‐Ting, Klotz‐Noack, Kathleen, Schwarz, Roland F, Sawitzki, Birgit, Kamphues, Carsten, Beule, Dieter, Landthaler, Markus, Sers, Christine, Horst, David, Blüthgen, Nils, Morkel, Markus
Published in EMBO molecular medicine (07.10.2021)
Published in EMBO molecular medicine (07.10.2021)
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Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
Ozkan-Dagliyan, Irem, Diehl, J. Nathaniel, George, Samuel D., Schaefer, Antje, Papke, Bjoern, Klotz-Noack, Kathleen, Waters, Andrew M., Goodwin, Craig M., Gautam, Prson, Pierobon, Mariaelena, Peng, Sen, Gilbert, Thomas S.K., Lin, Kevin H., Dagliyan, Onur, Wennerberg, Krister, Petricoin, Emanuel F., Tran, Nhan L., Bhagwat, Shripad V., Tiu, Ramon V., Peng, Sheng-Bin, Herring, Laura E., Graves, Lee M., Sers, Christine, Wood, Kris C., Cox, Adrienne D., Der, Channing J.
Published in Cell reports (Cambridge) (16.06.2020)
Published in Cell reports (Cambridge) (16.06.2020)
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SCFFbxw7/hCdc4 targets cyclin E2 for ubiquitin-dependent proteolysis
Klotz, Kathleen, Cepeda, Diana, Tan, YingMeei, Sun, Dahui, Sangfelt, Olle, Spruck, Charles
Published in Experimental cell research (01.07.2009)
Published in Experimental cell research (01.07.2009)
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SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells
Klotz-Noack, Kathleen, Klinger, Bertram, Rivera, Maria, Bublitz, Natalie, Uhlitz, Florian, Riemer, Pamela, Lüthen, Mareen, Sell, Thomas, Kasack, Katharina, Gastl, Bastian, Ispasanie, Sylvia S.S., Simon, Tincy, Janssen, Nicole, Schwab, Matthias, Zuber, Johannes, Horst, David, Blüthgen, Nils, Schäfer, Reinhold, Morkel, Markus, Sers, Christine
Published in Cell reports (Cambridge) (22.09.2020)
Published in Cell reports (Cambridge) (22.09.2020)
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FBXW7/hCDC4 is a general tumor suppressor in human cancer
AKHOONDI, Shahab, DAHUI SUN, MUELLER-HOLZNER, Elisabeth, CORCORAN, Martin, DAGNELL, Markus, SEPIDEH ZABIHI NEJAD, BABAK NOORI NAYER, MOHAMMAD REZA ZALI, HANSSON, Johan, EGYHAZI, Susanne, PETERSSON, Fredrik, SANGFELT, Per, VON DER LEHR, Natalie, NORDGREN, Hans, GRANDER, Dan, REED, Steven I, WIDSCHWENDTER, Martin, SANGFELT, Olle, SPRUCK, Charles, APOSTOLIDOU, Sophia, KLOTZ, Kathleen, MALJUKOVA, Alena, CEPEDA, Diana, FIEGL, Heidi, DOFOU, Dimitra, MARTH, Christian
Published in Cancer research (Chicago, Ill.) (01.10.2007)
Published in Cancer research (Chicago, Ill.) (01.10.2007)
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A cluster of ring stage-specific genes linked to a locus implicated in cytoadherence in Plasmodium falciparum codes for PEXEL-negative and PEXEL-positive proteins exported into the host cell
Spielmann, Tobias, Hawthorne, Paula L, Dixon, Matthew W A, Hannemann, Mandy, Klotz, Kathleen, Kemp, David J, Klonis, Nectarios, Tilley, Leann, Trenholme, Katharine R, Gardiner, Donald L
Published in Molecular biology of the cell (01.08.2006)
Published in Molecular biology of the cell (01.08.2006)
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Journal Article
SCF(Fbxw7/hCdc4) targets cyclin E2 for ubiquitin-dependent proteolysis
Klotz, Kathleen, Cepeda, Diana, Tan, Yingmeei, Sun, Dahui, Sangfelt, Olle, Spruck, Charles
Published in Experimental cell research (01.07.2009)
Published in Experimental cell research (01.07.2009)
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Journal Article
SCF Fbxw7/hCdc4 targets cyclin E2 for ubiquitin-dependent proteolysis
Klotz, Kathleen, Cepeda, Diana, Tan, YingMeei, Sun, Dahui, Sangfelt, Olle, Spruck, Charles
Published in Experimental cell research (2009)
Published in Experimental cell research (2009)
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Journal Article
Abstract A20: Depletion of replication factor MCM7 is synthetically lethal to oncogenic KRAS expression
Gastl, Bastian, Klotz-Noack, Kathleen, Klinger, Bertram, Zuber, Johannes, Blüthgen, Nils, Schäfer, Reinhold, Sers, Christine
Published in Molecular cancer therapeutics (01.10.2017)
Published in Molecular cancer therapeutics (01.10.2017)
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Abstract 5170: HDAC inhibitors and the mechanism of resistance in colorectal cancer: RAS and MYC - the partners in crime
Ispasanie, Sylvia S., Boehme, Lena, Eilers, Martin, Brummer, Tilman, Klotz-Noack, Kathleen, Kuhn, Natalia, Gastl, Bastian, Sers, Christine
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Mutation-specific effects of NRAS oncogenes in colorectal cancer cells
Kuhn, Natalia, Klinger, Bertram, Uhlitz, Florian, Sieber, Anja, Rivera, Maria, Klotz-Noack, Kathleen, Fichtner, Iduna, Hoffmann, Jens, Blüthgen, Nils, Falk, Christine, Sers, Christine, Schäfer, Reinhold
Published in Advances in biological regulation (01.01.2021)
Published in Advances in biological regulation (01.01.2021)
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Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe
Gastl, Bastian, Klotz-Noack, Kathleen, Klinger, Bertram, Ispasanie, Sylvia, Salib, Krenoula Hani Fouad, Zuber, Johannes, Mamlouk, Soulafa, Bublitz, Natalie, Blüthgen, Nils, Horst, David, Morkel, Markus, Schäfer, Reinhold, Sers, Christine
Published in Cell death & disease (01.07.2020)
Published in Cell death & disease (01.07.2020)
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PP2A-B55β Antagonizes Cyclin E1 Proteolysis and Promotes Its Dysregulation in Cancer
YINGMEEI TAN, DAHUI SUN, WEIJIAN JIANG, KLOTZ-NOACK, Kathleen, VASHISHT, Ajay A, WOHLSCHLEGEL, James, WIDSCHWENDTER, Martin, SPRUCK, Charles
Published in Cancer research (Chicago, Ill.) (01.04.2014)
Published in Cancer research (Chicago, Ill.) (01.04.2014)
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Journal Article
SFPQ Depletion Is Synthetically Lethal with BRAF V600E in Colorectal Cancer Cells
Klotz-Noack, Kathleen, Klinger, Bertram, Rivera, Maria, Bublitz, Natalie, Uhlitz, Florian, Riemer, Pamela, Lüthen, Mareen, Sell, Thomas, Kasack, Katharina, Gastl, Bastian, Ispasanie, Sylvia S S, Simon, Tincy, Janssen, Nicole, Schwab, Matthias, Zuber, Johannes, Horst, David, Blüthgen, Nils, Schäfer, Reinhold, Morkel, Markus, Sers, Christine
Published in Cell reports (Cambridge) (22.09.2020)
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Published in Cell reports (Cambridge) (22.09.2020)
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Proteolytic degradation of neuronal benzodiazepine binding sites
Klotz, K L, Bocchetta, A, Neale, J H, Thomas, J W, Tallman, J F
Published in Life sciences (1973) (01.01.1984)
Published in Life sciences (1973) (01.01.1984)
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Journal Article
Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer
Uhlitz, Florian, Bischoff, Philip, Peidli, Stefan, Sieber, Anja, Obermayer, Benedikt, Blanc, Eric, Trinks, Alexandra, Lüthen, Mareen, Ruchiy, Yana, Sell, Thomas, Mamlouk, Soulafa, Arsie, Roberto, Tzu-Ting Wei, Klotz-Noack, Kathleen, Schwarz, Roland F, Sawitzki, Birgit, Kamphues, Carsten, Beule, Dieter, Landthaler, Markus, Sers, Christine, Horst, David, Blüthgen, Nils, Morkel, Markus
Published in bioRxiv (11.02.2021)
Published in bioRxiv (11.02.2021)
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