Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer
Papachristofilou, Alexandros, Hipp, Madeleine M, Klinkhardt, Ute, Früh, Martin, Sebastian, Martin, Weiss, Christian, Pless, Miklos, Cathomas, Richard, Hilbe, Wolfgang, Pall, Georg, Wehler, Thomas, Alt, Jürgen, Bischoff, Helge, Geißler, Michael, Griesinger, Frank, Kallen, Karl-Josef, Fotin-Mleczek, Mariola, Schröder, Andreas, Scheel, Birgit, Muth, Anke, Seibel, Tobias, Stosnach, Claudia, Doener, Fatma, Hong, Henoch S, Koch, Sven D, Gnad-Vogt, Ulrike, Zippelius, Alfred
Published in Journal for immunotherapy of cancer (08.02.2019)
Published in Journal for immunotherapy of cancer (08.02.2019)
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Journal Article
A novel orf virus vector-based COVID-19 booster vaccine shows cross-neutralizing activity in the absence of anti-vector neutralizing immunity
Klinkardt, Ute, Schunk, Mirjam, Ervin, John, Schindler, Christoph, Sugimoto, Danny, Rankin, Bruce, Amann, Ralf, Monti, Martina, Kutschenko, Anna, Schumacher, Carsten, Huber, Kristina, Zeder, Andreas, Heikkila, Nelli, Didierlaurent, Arnaud M, Schwarz, Sylvia E, Derouazi, Madiha
Published in Human vaccines & immunotherapeutics (31.12.2024)
Published in Human vaccines & immunotherapeutics (31.12.2024)
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Journal Article
Novel Multi-Antigen Orf-Virus-Derived Vaccine Elicits Protective Anti-SARS-CoV-2 Response in Monovalent and Bivalent Formats
Burri, Dominique Julien, Renz, Louis, Mueller, Melanie, Pagallies, Felix, Klinkhardt, Ute, Amann, Ralf, Derouazi, Madiha
Published in Vaccines (Basel) (01.05.2024)
Published in Vaccines (Basel) (01.05.2024)
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Journal Article
The CX3C chemokine fractalkine mediates platelet adhesion via the von Willebrand receptor glycoprotein Ib
Meyer dos Santos, Sascha, Klinkhardt, Ute, Scholich, Klaus, Nelson, Karen, Monsefi, Nadejda, Deckmyn, Hans, Kuczka, Karina, Zorn, Anita, Harder, Sebastian
Published in Blood (05.05.2011)
Published in Blood (05.05.2011)
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Journal Article
Transition from argatroban to oral anticoagulation with phenprocoumon or acenocoumarol: effects on prothrombin time, activated partial thromboplastin time, and Ecarin Clotting Time
Harder, Sebastian, Graff, Jochen, Klinkhardt, Ute, von Hentig, Nils, Walenga, Jeanine M, Watanabe, Hikari, Osakabe, Masanori, Breddin, Hans-Klaus
Published in Thrombosis and haemostasis (01.06.2004)
Published in Thrombosis and haemostasis (01.06.2004)
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Journal Article
Angiotensin II infusion increases plasma erythropoietin levels via an angiotensin II type 1 receptor-dependent pathway
Gossmann, Jan, Burkhardt, Ralf, Harder, Sebastian, Lenz, Tomas, Sedlmeyer, Annette, Klinkhardt, Ute, Geiger, Helmut, Scheuermann, Ernst-Heinrich
Published in Kidney international (01.07.2001)
Published in Kidney international (01.07.2001)
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Journal Article
Close Relationship between the Platelet Activation Marker CD62 and the Granular Release of Platelet-Derived Growth Factor
Graff, Jochen, Klinkhardt, Ute, Schini-Kerth, Valérie B, Harder, Sebastian, Franz, Nicole, Bassus, Steffen, Kirchmaier, Carl M
Published in The Journal of pharmacology and experimental therapeutics (01.03.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2002)
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Journal Article
Abstract CT217: Phase I, first-in-human trial evaluating BI 1387446 (STING agonist) alone and in combination with ezabenlimab (BI 754091; anti-PD-1) in solid tumors
Harrington, Kevin, Parkes, Eileen, Weiss, Jared, Ingham, Mathew, Cervantes, Andrés, Calvo, Emiliano, Klinkhardt, Ute, Sikken, Patricia, Schmohl, Michael, Garralda, Elena
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 4522: Potent induction of a tumor-specific immune response by a cyclic dinucleotide STING agonist
Gremel, Gabriela, Impagnatiello, Maria A., Carotta, Sebastian, Schaaf, Otmar, Chetta, Paolo M., Oost, Thorsten, Zichner, Thomas, Hofmann, Marco, Blake, Sophia, Bretschneider, Tom, Fleck, Martin, Grube, Achim, Nar, Herbert, Rast, Georg, Schmidt, Esther, Klinkhardt, Ute, Arndt-Schmitz, Kirsten, Laux, Thorsten, Zinzalla, Vittoria, Sedgwick, Jonathon, Kraut, Norbert
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract LB-021: Intratumoral RNA-based TLR-7/-8 and RIG-I agonist CV8102 alone and in combination with anti-PD-1 in a Phase I dose-escalation and expansion trial in patients with advanced solid tumors
Eigentler, Thomas, Krauss, Juergen, Schreiber, Jutta, Weishaupt, Carsten, Terheyden, Patrick, Heinzerling, Lucie, Mohr, Peter, Weide, Benjamin, Gutzmer, Ralf, Becker, Juergen C., Kiecker, Felix, Daehling, Angelika, Funkner, Fatma, Heidenreich, Regina, Kays, Sarah-Katharina, Klinkhardt, Ute, Scheel, Birgit, Schoenborn-Kellenberger, Oliver, Seibel, Tobias, Stosnach, Claudia, Strack, Tanja, Gnad-Vogt, Ulrike
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Anticoagulation with argatroban for elective percutaneous coronary intervention: population pharmacokinetics and pharmacokinetic-pharmacodynamic relationship of coagulation parameters
Akimoto, Kei, Klinkhardt, Ute, Zeiher, Andreas, Niethammer, Margit, Harder, Sebastian
Published in Journal of clinical pharmacology (01.06.2011)
Published in Journal of clinical pharmacology (01.06.2011)
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Journal Article
Treatment outcome according to tumor RAS mutation status in OPUS study patients with metastatic colorectal cancer (mCRC) randomized to FOLFOX4 with/without cetuximab
Bokemeyer, Carsten, Kohne, Claus-Henning, Ciardiello, Fortunato, Lenz, Heinz-Josef, Heinemann, Volker, Klinkhardt, Ute, Beier, Frank, Duecker, Klaus, Tejpar, Sabine
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Clopidogrel but not aspirin reduces P-selectin expression and formation of platelet-leukocyte aggregates in patients with atherosclerotic vascular disease
Klinkhardt, Ute, Bauersachs, Rupert, Adams, Jan, Graff, Jochen, Lindhoff-Last, Edeltraud, Harder, Sebastian
Published in Clinical pharmacology and therapeutics (01.03.2003)
Published in Clinical pharmacology and therapeutics (01.03.2003)
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Journal Article
A novel μ-fluidic whole blood coagulation assay based on Rayleigh surface-acoustic waves as a point-of-care method to detect anticoagulants
Meyer dos Santos, Sascha, Zorn, Anita, Guttenberg, Zeno, Picard-Willems, Bettina, Kläffling, Christina, Nelson, Karen, Klinkhardt, Ute, Harder, Sebastian
Published in Biomicrofluidics (01.09.2013)
Published in Biomicrofluidics (01.09.2013)
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Journal Article
408 Phase I, first-in-human trial evaluating BI 1387446 (stimulator of interferon genes [STING] agonist) alone and combined with BI 754091 (anti-programmed cell death [PD]-1) in solid tumors
Harrington, Kevin, Parkes, Eileen, Weiss, Jared, Ingham, Mathew, Cervantes, Andrés, Calvo, Emiliano, Riese, Matthew, Klinkhardt, Ute, Sikken, Patricia, Schmohl, Michael, Garralda, Elena
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
The integrin antagonist, cilengitide, is a weak inhibitor of αIIbβ3 mediated platelet activation and inhibits platelet adhesion under flow
Meyer dos Santos, Sascha, Kuczka, Karina, Picard-Willems, Bettina, Nelson, Karen, Klinkhardt, Ute, Harder, Sebastian
Published in Platelets (Edinburgh) (01.02.2015)
Published in Platelets (Edinburgh) (01.02.2015)
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