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Vu, Ly P, Pickering, Brian F, Cheng, Yuanming, Zaccara, Sara, Nguyen, Diu, Minuesa, Gerard, Chou, Timothy, Chow, Arthur, Saletore, Yogesh, MacKay, Matthew, Schulman, Jessica, Famulare, Christopher, Patel, Minal, Klimek, Virginia M, Garrett-Bakelman, Francine E, Melnick, Ari, Carroll, Martin, Mason, Christopher E, Jaffrey, Samie R, Kharas, Michael G
Published in Nature medicine (01.11.2017)
Published in Nature medicine (01.11.2017)
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Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis
Gao, Teng, Ptashkin, Ryan, Bolton, Kelly L., Sirenko, Maria, Fong, Christopher, Spitzer, Barbara, Menghrajani, Kamal, Ossa, Juan E. Arango, Zhou, Yangyu, Bernard, Elsa, Levine, Max, Martinez, Juan S. Medina, Zhang, Yanming, Franch-Expósito, Sebastià, Patel, Minal, Braunstein, Lior Z., Kelly, Daniel, Yabe, Mariko, Benayed, Ryma, Caltabellotta, Nicole M., Philip, John, Paraiso, Ederlinda, Mantha, Simon, Solit, David B., Diaz, Luis A., Berger, Michael F., Klimek, Virginia, Levine, Ross L., Zehir, Ahmet, Devlin, Sean M., Papaemmanuil, Elli
Published in Nature communications (12.01.2021)
Published in Nature communications (12.01.2021)
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H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers
Seiler, Michael, Yoshimi, Akihide, Darman, Rachel, Chan, Betty, Keaney, Gregg, Thomas, Michael, Agrawal, Anant A, Caleb, Benjamin, Csibi, Alfredo, Sean, Eckley, Fekkes, Peter, Karr, Craig, Klimek, Virginia, Lai, George, Lee, Linda, Kumar, Pavan, Lee, Stanley Chun-Wei, Liu, Xiang, Mackenzie, Crystal, Meeske, Carol, Mizui, Yoshiharu, Padron, Eric, Park, Eunice, Pazolli, Ermira, Peng, Shouyong, Prajapati, Sudeep, Taylor, Justin, Teng, Teng, Wang, John, Warmuth, Markus, Yao, Huilan, Yu, Lihua, Zhu, Ping, Abdel-Wahab, Omar, Smith, Peter G, Buonamici, Silvia
Published in Nature medicine (01.04.2018)
Published in Nature medicine (01.04.2018)
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Phase IIB Trial of Oral Midostaurin (PKC412), the FMS-Like Tyrosine Kinase 3 Receptor (FLT3) and Multi-Targeted Kinase Inhibitor, in Patients With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome With Either Wild-Type or Mutated FLT3
FISCHER, Thomas, STONE, Richard M, KLIMEK, Virginia M, NIMER, Stephen D, GILLILAND, D. Gary, DUTREIX, Catherine, HUNTSMAN-LABED, Alice, VIRKUS, Jodi, GILES, Francis J, DEANGELO, Daniel J, GALINSKY, Ilene, ESTEY, Elihu, LANZA, Carlo, FOX, Edward, EHNINGER, Gerhard, FELDMAN, Eric J, SCHILLER, Gary J
Published in Journal of clinical oncology (01.10.2010)
Published in Journal of clinical oncology (01.10.2010)
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Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
Kotini, Andriana G., Chang, Chan-Jung, Chow, Arthur, Yuan, Han, Ho, Tzu-Chieh, Wang, Tiansu, Vora, Shailee, Solovyov, Alexander, Husser, Chrystel, Olszewska, Malgorzata, Teruya-Feldstein, Julie, Perumal, Deepak, Klimek, Virginia M., Spyridonidis, Alexandros, Rampal, Raajit K., Silverman, Lewis, Reddy, E. Premkumar, Papaemmanuil, Elli, Parekh, Samir, Greenbaum, Benjamin D., Leslie, Christina S., Kharas, Michael G., Papapetrou, Eirini P.
Published in Cell stem cell (02.03.2017)
Published in Cell stem cell (02.03.2017)
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CD99 is a therapeutic target on disease stem cells in myeloid malignancies
Chung, Stephen S, Eng, William S, Hu, Wenhuo, Khalaj, Mona, Garrett-Bakelman, Francine E, Tavakkoli, Montreh, Levine, Ross L, Carroll, Martin, Klimek, Virginia M, Melnick, Ari M, Park, Christopher Y
Published in Science translational medicine (25.01.2017)
Published in Science translational medicine (25.01.2017)
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Progression of RAS-Mutant Leukemia during RAF Inhibitor Treatment
Callahan, Margaret K, Rampal, Raajit, Harding, James J, Klimek, Virginia M, Chung, Young Rock, Merghoub, Taha, Wolchok, Jedd D, Solit, David B, Rosen, Neal, Abdel-Wahab, Omar, Levine, Ross L, Chapman, Paul B
Published in The New England journal of medicine (13.12.2012)
Published in The New England journal of medicine (13.12.2012)
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Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells
Kotini, Andriana G, Chang, Chan-Jung, Boussaad, Ibrahim, Delrow, Jeffrey J, Dolezal, Emily K, Nagulapally, Abhinav B, Perna, Fabiana, Fishbein, Gregory A, Klimek, Virginia M, Hawkins, R David, Huangfu, Danwei, Murry, Charles E, Graubert, Timothy, Nimer, Stephen D, Papapetrou, Eirini P
Published in Nature biotechnology (01.06.2015)
Published in Nature biotechnology (01.06.2015)
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Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML
Yoshimi, Akihide, Balasis, Maria E., Vedder, Alexis, Feldman, Kira, Ma, Yan, Zhang, Hailing, Lee, Stanley Chun-Wei, Letson, Christopher, Niyongere, Sandrine, Lu, Sydney X., Ball, Markus, Taylor, Justin, Zhang, Qing, Zhao, Yulong, Youssef, Salma, Chung, Young Rock, Zhang, Xiao Jing, Durham, Benjamin H., Yang, Wendy, List, Alan F., Loh, Mignon L., Klimek, Virginia, Berger, Michael F., Stieglitz, Elliot, Padron, Eric, Abdel-Wahab, Omar
Published in Blood (27.07.2017)
Published in Blood (27.07.2017)
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Giving Voice to Patient Values Throughout Cancer: A Novel Nurse-Led Intervention
Epstein, Andrew S., Desai, Anjali V., Bernal, Camila, Romano, Danielle, Wan, Peter J., Okpako, Molly, Anderson, Kelly, Chow, Kimberly, Kramer, Dana, Calderon, Claudia, Klimek, Virginia V., Rawlins-Duell, Robin, Reidy, Diane L., Goldberg, Jessica I., Cruz, Elizabeth, Nelson, Judith E.
Published in Journal of pain and symptom management (01.07.2019)
Published in Journal of pain and symptom management (01.07.2019)
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Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia
Shih, Alan H, Chung, Stephen S, Dolezal, Emily K, Zhang, Su-Jiang, Abdel-Wahab, Omar I, Park, Christopher Y, Nimer, Stephen D, Levine, Ross L, Klimek, Virginia M
Published in Haematologica (Roma) (01.06.2013)
Published in Haematologica (Roma) (01.06.2013)
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Phase 2 study of lenalidomide in transfusion-dependent, low-risk, and intermediate-1–risk myelodysplastic syndromes with karyotypes other than deletion 5q
Raza, Azra, Reeves, James A., Feldman, Eric J., Dewald, Gordon W., Bennett, John M., Deeg, H. Joachim, Dreisbach, Luke, Schiffer, Charles A., Stone, Richard M., Greenberg, Peter L., Curtin, Peter T., Klimek, Virginia M., Shammo, Jamile M., Thomas, Deborah, Knight, Robert D., Schmidt, Michele, Wride, Kenton, Zeldis, Jerome B., List, Alan F.
Published in Blood (01.01.2008)
Published in Blood (01.01.2008)
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Navigating a newly diagnosed cancer through clinician-facilitated discussions of health-related patient values: a qualitative analysis
Lynch, Kathleen A, Bernal, Camila, Romano, Danielle R, Shin, Paul, Nelson, Judith E, Okpako, Molly, Anderson, Kelley, Cruz, Elizabeth, Desai, Anjali V, Klimek, Virginia M, Epstein, Andrew S
Published in BMC palliative care (06.03.2022)
Published in BMC palliative care (06.03.2022)
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Molecular taxonomy of myelodysplastic syndromes and its clinical implications
Bernard, Elsa, Hasserjian, Robert P., Greenberg, Peter L., Arango Ossa, Juan E., Creignou, Maria, Tuechler, Heinz, Gutierrez-Abril, Jesus, Domenico, Dylan, Medina-Martinez, Juan S., Levine, Max, Liosis, Konstantinos, Farnoud, Noushin, Sirenko, Maria, Jädersten, Martin, Germing, Ulrich, Sanz, Guillermo, van de Loosdrecht, Arjan A., Nannya, Yasuhito, Kosmider, Olivier, Follo, Matilde Y., Thol, Felicitas, Zamora, Lurdes, Pinheiro, Ronald F., Pellagatti, Andrea, Elias, Harold K., Haase, Detlef, Ganster, Christina, Ades, Lionel, Tobiasson, Magnus, Palomo, Laura, Della Porta, Matteo Giovanni, Fenaux, Pierre, Belickova, Monika, Savona, Michael R., Klimek, Virginia M., Santos, Fabio P. S., Boultwood, Jacqueline, Kotsianidis, Ioannis, Santini, Valeria, Solé, Francesc, Platzbecker, Uwe, Heuser, Michael, Valent, Peter, Finelli, Carlo, Voso, Maria Teresa, Shih, Lee-Yung, Fontenay, Michaela, Jansen, Joop H., Cervera, José, Gattermann, Norbert, Ebert, Benjamin L., Bejar, Rafael, Malcovati, Luca, Ogawa, Seishi, Cazzola, Mario, Hellström-Lindberg, Eva, Papaemmanuil, Elli
Published in Blood (10.10.2024)
Published in Blood (10.10.2024)
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Micafungin versus posaconazole prophylaxis in acute leukemia or myelodysplastic syndrome: A randomized study
Epstein, David J., Seo, Susan K., Huang, Yao-Ting, Park, Jay H., Klimek, Virginia M., Berman, Ellin, Tallman, Martin S., Frattini, Mark G., Papanicolaou, Genovefa A.
Published in The Journal of infection (01.09.2018)
Published in The Journal of infection (01.09.2018)
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Tolerability, Pharmacodynamics, and Pharmacokinetics Studies of Depsipeptide (Romidepsin) in Patients with Acute Myelogenous Leukemia or Advanced Myelodysplastic Syndromes
KLIMEK, Virginia M, FIRCANIS, Sophia, MASLAK, Peter, GUERNAH, Llhem, BAUM, Michael, NIAN WU, PANAGEAS, Katherine, WRIGHT, John J, PAOLO PANDOLFI, Pier, NIMER, Stephen D
Published in Clinical cancer research (01.02.2008)
Published in Clinical cancer research (01.02.2008)
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Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study
Wesa, Kathleen M., Cunningham-Rundles, Susanna, Klimek, Virginia M., Vertosick, Emily, Coleton, Marci I., Yeung, K. Simon, Lin, Hong, Nimer, Stephen, Cassileth, Barrie R.
Published in Cancer Immunology, Immunotherapy (01.02.2015)
Published in Cancer Immunology, Immunotherapy (01.02.2015)
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