G‑Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5) Agonists Reduce the Production of Proinflammatory Cytokines and Stabilize the Alternative Macrophage Phenotype
Högenauer, Klemens, Arista, Luca, Schmiedeberg, Niko, Werner, Gudrun, Jaksche, Herbert, Bouhelal, Rochdi, Nguyen, Deborah G, Bhat, B. Ganesh, Raad, Layla, Rauld, Celine, Carballido, José M
Published in Journal of medicinal chemistry (26.12.2014)
Published in Journal of medicinal chemistry (26.12.2014)
Get full text
Journal Article
Total Synthesis of Five Thapsigargins: Guaianolide Natural Products Exhibiting Sub-Nanomolar SERCA Inhibition
Andrews, Stephen P., Ball, Matthew, Wierschem, Frank, Cleator, Ed, Oliver, Steven, Högenauer, Klemens, Simic, Oliver, Antonello, Alessandra, Hünger, Udo, Smith, Martin D., Ley, Steven V.
Published in Chemistry : a European journal (06.07.2007)
Published in Chemistry : a European journal (06.07.2007)
Get full text
Journal Article
A Route to the Thapsigargins from (S)-Carvone Providing a Substrate-Controlled Total Synthesis of Trilobolide, Nortrilobolide, and Thapsivillosin F
Oliver, Steven F., Högenauer, Klemens, Simic, Oliver, Antonello, Alessandra, Smith, Martin D., Ley, Steven V.
Published in Angewandte Chemie International Edition (15.12.2003)
Published in Angewandte Chemie International Edition (15.12.2003)
Get full text
Journal Article
Synthesis of the thapsigargins
Ley, S.V, Antonello, A, Balskus, E.P, Booth, D.T, Christensen, S.B, Cleator, E, Gold, H, Hogenauer, K, Hunger, U, Myers, R.M
Published in Proceedings of the National Academy of Sciences - PNAS (17.08.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (17.08.2004)
Get full text
Journal Article
S1P receptor mediated activity of FTY720 phosphate mimics
Högenauer, Klemens, Hinterding, Klaus, Nussbaumer, Peter
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Get full text
Journal Article
One-step labelling of sphingolipids via a scrambling cross-metathesis reaction
Nussbaumer, P, Ettmayer, P, Peters, C, Rosenbeiger, D, Hogenauer, K
Published in Chemical communications (Cambridge, England) (28.10.2005)
Published in Chemical communications (Cambridge, England) (28.10.2005)
Get more information
Journal Article
DIHYDRO-BENZO-OXAZINE AND DIHYDRO-PYRIDO-OXAZINE DERIVATIVES
KAMMERTOENS, KAREN, KALIS, CHRISTOPH, MOEBITZ, HENRIK, CARAVATTI, GIORGIO, WOLF, ROMAIN, CHAMOIN, SYLVIE, HOGENAUER, KLEMENS, SOLDERMANN, NICOLAS, ZECRI, FREDERIC, SMITH, ALEXANDER BAXTER, FURET, PASCAL, LEWIS, IAN, HURTH, KONSTANZE
Year of Publication 31.12.2019
Get full text
Year of Publication 31.12.2019
Patent
DIHYDRO-BENZO-OXAZINE AND DIHYDRO-PYRIDO-OXAZINE DERIVATIVES
ZECRI,FREDERIC, KAMMERTOENS, KAREN, KALIS, CHRISTOPH, MOEBITZ, HENRIK, CARAVATTI, GIORGIO, CHAMOIN, SYLVIE, SMITH,ALEXANDER BAXTER, SOLDERMANN,NICOLAS, HOGENAUER, KLEMENS, FURET, PASCAL, WOLF,ROMAIN, LEWIS, IAN, HURTH, KONSTANZE
Year of Publication 18.09.2019
Get full text
Year of Publication 18.09.2019
Patent
USE OF INHIBITORS OF THE ACTIVITY OR FUNCTION OF PI3K
KALIS, CHRISTOPH, STRANG, ROSS, WOLF, ROMAIN, HOGENAUER, KLEMENS, SOLDERMANN, NICOLAS, ZECRI, FREDERIC, STOWASSER, FRANK, TUFILLI, NICOLA, SMITH, ALEXANDER BAXTER, FERNANDES GOMES DOS SANTOS, PAULO ANTONIO, COOKE, NIGEL GRAHAM, FURET, PASCAL, HEBACH, CHRISTINA, HOLLINGWORTH, GREGORY, LEWIS, IAN, VON MATT, ANETTE, STAUFFER, FREDERIC
Year of Publication 25.08.2020
Get full text
Year of Publication 25.08.2020
Patent
2,3-Dihydro-benzo(1,4)oxazine derivatives and related compounds as phosphoinositide-3 kinase (PI3K) inhibitors for the treatment of e.g. rheumatoid arthritis
SOLDERMANN Nicolas, LEWIS Ian, MOEBITZ Henrik, SMITH Alexander Baxter, ZECRI Frederic, KAMMERTOENS Karen, CARAVATTI Giorgio, WOLF Romain, CHAMOIN Sylvie, HURTH Konstanze, FURET Pascal, HOGENAUER Klemens, KALIS Christoph
Year of Publication 30.03.2018
Get full text
Year of Publication 30.03.2018
Patent
Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives
Smith Alexander Baxter, Hogenauer Klemens, Wolf Romain, Zecri Frederic, Furet Pascal, Moebitz Henrik, Caravatti Giorgio, Hurth Konstanze, Kammertoens Karen, Lewis Ian, Soldermann Nicolas, Chamoin Sylvie
Year of Publication 19.09.2017
Get full text
Year of Publication 19.09.2017
Patent
Quinoline Derivatives
ZECRI FREDERIC, SOLDERMANN NICOLAS, HURTH KONSTANZE, HOGENAUER KLEMENS, KALIS CHRISTOPH, MOEBITZ HENRIK
Year of Publication 28.05.2015
Get full text
Year of Publication 28.05.2015
Patent