Pharmacovigilance‐based drug repurposing: The search for inverse signals via OpenVigil identifies putative drugs against viral respiratory infections
Böhm, Ruwen, Bulin, Claudia, Waetzig, Vicki, Cascorbi, Ingolf, Klein, Hans‐Joachim, Herdegen, Thomas
Published in British journal of clinical pharmacology (01.11.2021)
Published in British journal of clinical pharmacology (01.11.2021)
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Journal Article
An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome
Ng, Bernard, White, Charles C, Klein, Hans-Ulrich, Sieberts, Solveig K, McCabe, Cristin, Patrick, Ellis, Xu, Jishu, Yu, Lei, Gaiteri, Chris, Bennett, David A, Mostafavi, Sara, De Jager, Philip L
Published in Nature neuroscience (01.10.2017)
Published in Nature neuroscience (01.10.2017)
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Journal Article
Low-Field Magnetic Resonance Imaging
Klein, Hans-Martin
Published in RöFo : Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebende Verfahren (01.06.2020)
Published in RöFo : Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebende Verfahren (01.06.2020)
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Journal Article
Considerations for integrative multi‐omic approaches to explore Alzheimer's disease mechanisms
Ma, Yiyi, Klein, Hans‐Ulrich, De Jager, Philip L.
Published in Brain pathology (Zurich, Switzerland) (01.09.2020)
Published in Brain pathology (Zurich, Switzerland) (01.09.2020)
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Journal Article
The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes
Beumer, Wouter, Gibney, Sinead M., Drexhage, Roosmarijn C., Pont‐Lezica, Lorena, Doorduin, Janine, Klein, Hans C., Steiner, Johann, Connor, Thomas J., Harkin, Andrew, Versnel, Marjan A., Drexhage, Hemmo A.
Published in Journal of leukocyte biology (01.11.2012)
Published in Journal of leukocyte biology (01.11.2012)
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Journal Article
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease
Mostafavi, Sara, Gaiteri, Chris, Sullivan, Sarah E., White, Charles C., Tasaki, Shinya, Xu, Jishu, Taga, Mariko, Klein, Hans-Ulrich, Patrick, Ellis, Komashko, Vitalina, McCabe, Cristin, Smith, Robert, Bradshaw, Elizabeth M., Root, David E., Regev, Aviv, Yu, Lei, Chibnik, Lori B., Schneider, Julie A., Young-Pearse, Tracy L., Bennett, David A., De Jager, Philip L.
Published in Nature neuroscience (01.06.2018)
Published in Nature neuroscience (01.06.2018)
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Journal Article
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia
Göllner, Stefanie, Oellerich, Thomas, Agrawal-Singh, Shuchi, Schenk, Tino, Klein, Hans-Ulrich, Rohde, Christian, Pabst, Caroline, Sauer, Tim, Lerdrup, Mads, Tavor, Sigal, Stölzel, Friedrich, Herold, Sylvia, Ehninger, Gerhard, Köhler, Gabriele, Pan, Kuan-Ting, Urlaub, Henning, Serve, Hubert, Dugas, Martin, Spiekermann, Karsten, Vick, Binje, Jeremias, Irmela, Berdel, Wolfgang E, Hansen, Klaus, Zelent, Arthur, Wickenhauser, Claudia, Müller, Lutz P, Thiede, Christian, Müller-Tidow, Carsten
Published in Nature medicine (01.01.2017)
Published in Nature medicine (01.01.2017)
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Journal Article
The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes
Grodstein, Francine, Lemos, Bernardo, Yu, Lei, Klein, Hans-Ulrich, Iatrou, Artemis, Buchman, Aron S., Shireby, Gemma L., Mill, Jonathan, Schneider, Julie A., De Jager, Philip L., Bennett, David A.
Published in Neurobiology of disease (01.09.2021)
Published in Neurobiology of disease (01.09.2021)
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Journal Article
Anti-inflammatory treatment for major depressive disorder: implications for patients with an elevated immune profile and non-responders to standard antidepressant therapy
Kopschina Feltes, Paula, Doorduin, Janine, Klein, Hans C, Juárez-Orozco, Luis Eduardo, Dierckx, Rudi AJO, Moriguchi-Jeckel, Cristina M, de Vries, Erik FJ
Published in Journal of Psychopharmacology (01.09.2017)
Published in Journal of Psychopharmacology (01.09.2017)
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Book Review
Journal Article
Tau Activates Transposable Elements in Alzheimer’s Disease
Guo, Caiwei, Jeong, Hyun-Hwan, Hsieh, Yi-Chen, Klein, Hans-Ulrich, Bennett, David A., De Jager, Philip L., Liu, Zhandong, Shulman, Joshua M.
Published in Cell reports (Cambridge) (05.06.2018)
Published in Cell reports (Cambridge) (05.06.2018)
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Journal Article
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
Schenk, Tino, Chen, Weihsu Claire, Göllner, Stefanie, Howell, Louise, Jin, Liqing, Hebestreit, Katja, Klein, Hans-Ulrich, Popescu, Andreea C, Burnett, Alan, Mills, Ken, Casero, Robert A, Marton, Laurence, Woster, Patrick, Minden, Mark D, Dugas, Martin, Wang, Jean C Y, Dick, John E, Müller-Tidow, Carsten, Petrie, Kevin, Zelent, Arthur
Published in Nature medicine (01.04.2012)
Published in Nature medicine (01.04.2012)
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Journal Article
Epigenetic dysregulation of KCa3.1 channels induces poor prognosis in lung cancer
Bulk, Etmar, Ay, Anne‐Sophie, Hammadi, Mehdi, Ouadid‐Ahidouch, Halima, Schelhaas, Sonja, Hascher, Antje, Rohde, Christian, Thoennissen, Nils H., Wiewrodt, Rainer, Schmidt, Eva, Marra, Alessandro, Hillejan, Ludger, Jacobs, Andreas H., Klein, Hans‐Ulrich, Dugas, Martin, Berdel, Wolfgang E., Müller‐Tidow, Carsten, Schwab, Albrecht
Published in International journal of cancer (01.09.2015)
Published in International journal of cancer (01.09.2015)
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Journal Article
Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer's disease brain
Klein, Hans-Ulrich, Trumpff, Caroline, Yang, Hyun-Sik, Lee, Annie J, Picard, Martin, Bennett, David A, De Jager, Philip L
Published in Molecular neurodegeneration (06.11.2021)
Published in Molecular neurodegeneration (06.11.2021)
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Journal Article