Lack of Gα i2 leads to dilative cardiomyopathy and increased mortality in β 1 -adrenoceptor overexpressing mice
Keller, Kirsten, Maass, Martina, Dizayee, Sara, Leiss, Veronika, Annala, Suvi, Köth, Jessica, Seemann, Wiebke K., Müller-Ehmsen, Jochen, Mohr, Klaus, Nürnberg, Bernd, Engelhardt, Stefan, Herzig, Stefan, Birnbaumer, Lutz, Matthes, Jan
Published in Cardiovascular research (01.12.2015)
Published in Cardiovascular research (01.12.2015)
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Design, Synthesis, and Action of Oxotremorine-Related Hybrid-Type Allosteric Modulators of Muscarinic Acetylcholine Receptors
Disingrini, Teresa, Muth, Mathias, Dallanoce, Clelia, Barocelli, Elisabetta, Bertoni, Simona, Kellershohn, Kerstin, Mohr, Klaus, De Amici, Marco, Holzgrabe, Ulrike
Published in Journal of medicinal chemistry (12.01.2006)
Published in Journal of medicinal chemistry (12.01.2006)
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Journal Article
Critical Amino Acid Residues of the Common Allosteric Site on the M 2 Muscarinic Acetylcholine Receptor: More Similarities than Differences between the Structurally Divergent Agents Gallamine and Bis(ammonio)alkane-Type Hexamethylene- bis -[dimethyl-(3-phthalimidopropyl)ammonium]dibromide
Huang, Xi-Ping, Prilla, Stefanie, Mohr, Klaus, Ellis, John
Published in Molecular pharmacology (01.09.2005)
Published in Molecular pharmacology (01.09.2005)
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Journal Article
Anterior screw fixation in type II odontoid fractures: is there a difference in outcome between age groups?
Börm, Wolfgang, Kast, Erich, Richter, Hans-Peter, Mohr, Klaus
Published in Neurosurgery (01.05.2003)
Published in Neurosurgery (01.05.2003)
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Journal Article
Rational design of dualsteric GPCR ligands: quests and promise : Molecular pharmacology of G protein-coupled receptors
MOHR, Klaus, TRÄNKLE, Christian, KOSTENIS, Evi, BAROCELLI, Elisabetta, DE AMICI, Marco, HOLZGRABE, Ulrike
Published in British journal of pharmacology (2010)
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Published in British journal of pharmacology (2010)
Journal Article
A biased ligand for OXE-R uncouples G[alpha] and G[beta][gamma] signaling within a heterotrimer
Blättermann, Stefanie, Peters, Lucas, Ottersbach, Philipp Aaron, Bock, Andreas, Konya, Viktoria, Weaver, C David, Gonzalez, Angel, Schröder, Ralf, Tyagi, Rahul, Luschnig, Petra, Gäb, Jürgen, Hennen, Stephanie, Ulven, Trond, Pardo, Leonardo, Mohr, Klaus, Gütschow, Michael, Heinemann, Akos, Kostenis, Evi
Published in Nature chemical biology (01.07.2012)
Published in Nature chemical biology (01.07.2012)
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Journal Article
Allosteric ligands for G protein-coupled receptors: A novel strategy with attractive therapeutic opportunities: ALLOSTERIC LIGANDS FOR G PROTEIN-COUPLED RECEPTORS
De Amici, Marco, Dallanoce, Clelia, Holzgrabe, Ulrike, Tränkle, Christian, Mohr, Klaus
Published in Medicinal research reviews (01.05.2010)
Published in Medicinal research reviews (01.05.2010)
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Journal Article
Allosteric Site on Muscarinic Acetylcholine Receptors: Identification of Two Amino Acids in the Muscarinic M 2 Receptor That Account Entirely for the M 2 /M 5 Subtype Selectivities of Some Structurally Diverse Allosteric Ligands in N -Methylscopolamine-Occupied Receptors
Voigtländer, Uta, Jöhren, Kirstin, Mohr, Marion, Raasch, Alexandra, Tränkle, Christian, Buller, Stefan, Ellis, John, Höltje, Hans-Dieter, Mohr, Klaus
Published in Molecular pharmacology (01.07.2003)
Published in Molecular pharmacology (01.07.2003)
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Journal Article
Spinal hematoma unrelated to previous surgery: analysis of 15 consecutive cases treated in a single institution within a 10-year period
Börm, Wolfgang, Mohr, Klaus, Hassepass, Uwe, Richter, Hans-Peter, Kast, Erich
Published in Spine (Philadelphia, Pa. 1976) (15.12.2004)
Published in Spine (Philadelphia, Pa. 1976) (15.12.2004)
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Journal Article
Interactions of Orthosteric and Allosteric Ligands with [ 3 H]Dimethyl-W84 at the Common Allosteric Site of Muscarinic M 2 Receptors
Tränkle, Christian, Weyand, Oliver, Voigtländer, Uta, Mynett, Anita, Lazareno, Sebastian, Birdsall, Nigel J. M., Mohr, Klaus
Published in Molecular pharmacology (01.07.2003)
Published in Molecular pharmacology (01.07.2003)
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Journal Article
Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M 2 and M 2 /M 5 Chimeric Receptors
Tränkle, Christian, Dittmann, Andreas, Schulz, Uwe, Weyand, Oliver, Buller, Stefan, Jöhren, Kirstin, Heller, Eberhard, Birdsall, Nigel J. M., Holzgrabe, Ulrike, Ellis, John, Höltje, Hans Dieter, Mohr, Klaus
Published in Molecular pharmacology (01.12.2005)
Published in Molecular pharmacology (01.12.2005)
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Journal Article
Synthesis and in vitro evaluation of a selective antagonist and the corresponding radioligand for the prostaglandin D 2 receptor CRTH2
Ulven, Trond, Gallen, Michael J., Nielsen, Mads C., Merten, Nicole, Schmidt, Carola, Mohr, Klaus, Tränkle, Christian, Kostenis, Evi
Published in Bioorganic & medicinal chemistry letters (01.11.2007)
Published in Bioorganic & medicinal chemistry letters (01.11.2007)
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Journal Article
Two-point kinetic experiments to quantify allosteric effects on radioligand dissociation
Kostenis, Evi, Mohr, Klaus
Published in Trends in pharmacological sciences (Regular ed.) (01.08.1996)
Published in Trends in pharmacological sciences (Regular ed.) (01.08.1996)
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Journal Article
Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist
Grossmüller, Maren, Antony, Johannes, Tränkle, Christian, Holzgrabe, Ulrike, Mohr, Klaus
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.01.2006)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.01.2006)
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