The Role of Neutrophil Elastase Inhibitors in Lung Diseases
Polverino, Eva, Rosales-Mayor, Edmundo, Dale, Glenn E, Dembowsky, Klaus, Torres, Antoni
Published in Chest (01.08.2017)
Published in Chest (01.08.2017)
Get more information
Journal Article
Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells
Karpova, Darja, Ritchey, Julie K., Holt, Matthew S., Abou-Ezzi, Grazia, Monlish, Darlene, Batoon, Lena, Millard, Susan, Spohn, Gabriele, Wiercinska, Eliza, Chendamarai, Ezhil, Yang, Wei, Christ, Stephanie, Gehrs, Leah, Schuettpelz, Laura G., Dembowsky, Klaus, Pettit, Allison R., Rettig, Michael P., Bonig, Halvard, DiPersio, John F.
Published in Blood (25.05.2017)
Published in Blood (25.05.2017)
Get full text
Journal Article
CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer
Xiang, Jingyu, Hurchla, Michelle A, Fontana, Francesca, Su, Xinming, Amend, Sarah R, Esser, Alison K, Douglas, Garry J, Mudalagiriyappa, Chidananda, Luker, Kathryn E, Pluard, Timothy, Ademuyiwa, Foluso O, Romagnoli, Barbara, Tuffin, Gérald, Chevalier, Eric, Luker, Gary D, Bauer, Michael, Zimmermann, Johann, Aft, Rebecca L, Dembowsky, Klaus, Weilbaecher, Katherine N
Published in Molecular cancer therapeutics (01.11.2015)
Published in Molecular cancer therapeutics (01.11.2015)
Get full text
Journal Article
Characterizing and targeting CD44v6+ cells in liver carcinoma
Srikanth, Akshaya, Dembowsky, Klaus, Schirmbeck, Reinhold, Lechel, André
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
Get full text
Journal Article
C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function
Wang, Yong, Dembowsky, Klaus, Chevalier, Eric, Stüve, Philipp, Korf-Klingebiel, Mortimer, Lochner, Matthias, Napp, L Christian, Frank, Heike, Brinkmann, Eva, Kanwischer, Anna, Bauersachs, Johann, Gyöngyösi, Mariann, Sparwasser, Tim, Wollert, Kai C
Published in Circulation (New York, N.Y.) (09.04.2019)
Published in Circulation (New York, N.Y.) (09.04.2019)
Get full text
Journal Article
Multifaceted C-X-C Chemokine Receptor 4 (CXCR4) Inhibition Interferes with Anti–Vascular Endothelial Growth Factor Therapy–Induced Glioma Dissemination
Gagner, Jean-Pierre, Sarfraz, Yasmeen, Ortenzi, Valerio, Alotaibi, Fawaz M., Chiriboga, Luis A., Tayyib, Awab T., Douglas, Garry J., Chevalier, Eric, Romagnoli, Barbara, Tuffin, Gérald, Schmitt, Michel, Lemercier, Guillaume, Dembowsky, Klaus, Zagzag, David
Published in The American journal of pathology (01.09.2017)
Published in The American journal of pathology (01.09.2017)
Get full text
Journal Article
Potent Stem Cell Mobilization with the Novel CXCR4 Antagonist POL6326 - Results of a Phase IIa Dose Escalation Study in Comparison to G-CSF
Karpova, Darja, Brauninger, Susanne, Wiercinska, Eliza, Kraemer, Ariane, Stock, Belinda, Graff, Jochen, Escot, Christophe, Douglas, Garry, Romagnoli, Barbara, Chevalier, Eric, Dembowsky, Klaus, Hooftman, Leon, Bonig, Halvard
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
Get full text
Journal Article
Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma
Barone, Amy, Sengupta, Rajarshi, Warrington, Nicole M, Smith, Erin, Wen, Patrick Y, Brekken, Rolf A, Romagnoli, Barbara, Douglas, Garry, Chevalier, Eric, Bauer, Michael P, Dembowsky, Klaus, Piwnica-Worms, David, Rubin, Joshua B
Published in Oncotarget (30.10.2014)
Published in Oncotarget (30.10.2014)
Get full text
Journal Article
The Novel CXCR4 Antagonist POL5551 Decreases Surface CXCR4 (s-CXCR4) Expression, Inhibits Chemotaxis, and Enhances Chemosensitivity in Acute Lymphoblastic Leukemia (ALL)
Sison, Edward Allan R., Magoon, Daniel, Chevalier, Eric, Dembowsky, Klaus, Brown, Patrick
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
Get full text
Journal Article
Abstract A20: A novel CXCR4 antagonist interferes with antivascular endothelial growth factor therapy-induced glioma dissemination
Gagner, Jean-Pierre, Sarfraz, Yasmeen, Alotaibi, Fawaz M., Ortenzi, Valerio, Tayyib, Awab T., Chiriboga, Luis A., Douglas, Garry J., Chevalier, Eric, Romagnoli, Barbara, Tuffin, Gerald, Dembowsky, Klaus, Zagzag, David
Published in Cancer research (Chicago, Ill.) (01.12.2015)
Published in Cancer research (Chicago, Ill.) (01.12.2015)
Get full text
Journal Article
Abstract 1114: Combination of a novel CXCR4 antagonist with chemotherapy reduces breast cancer bone metastatic tumor burden
Xiang, Jingyu, Hurchla, Michelle A., Luker, Kathryn, Douglas, Garry, Romagnoli, Barbara, Chevalier, Eric, Bauer, Michael, Zimmermann, Johann, Dembowsky, Klaus, Luker, Gary, Weilbaecher, Katherine N.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article
NO-independent regulatory site on soluble guanylate cyclase
Stasch, Johannes-Peter, Becker, Eva Maria, Alonso-Alija, Cristina, Apeler, Heiner, Dembowsky, Klaus, Feurer, Achim, Gerzer, Rupert, Minuth, Torsten, Perzborn, Elisabeth, Pleiß, Ulrich, Schröder, Henning, Schroeder, Werner, Stahl, Elke, Steinke, Wolfram, Straub, Alexander, Schramm, Matthias
Published in Nature (London) (08.03.2001)
Published in Nature (London) (08.03.2001)
Get full text
Journal Article
The CXCR4 antagonist POL5551 is equally effective as sirolimus in reducing neointima formation without impairing re-endothelialisation
Hamesch, Karim, Subramanian, Pallavi, Li, Xiaofeng, Dembowsky, Klaus, Chevalier, Eric, Weber, Christian, Schober, Andreas
Published in Thrombosis and haemostasis (01.02.2012)
Published in Thrombosis and haemostasis (01.02.2012)
Get more information
Journal Article
NO‐ and haem‐independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle
Stasch, Johannes‐Peter, Schmidt, Peter, Alonso‐Alija, Cristina, Apeler, Heiner, Dembowsky, Klaus, Haerter, Michael, Heil, Markus, Minuth, Torsten, Perzborn, Elisabeth, Pleiss, Ulrich, Schramm, Matthias, Schroeder, Werner, Schröder, Henning, Stahl, Elke, Steinke, Wolfram, Wunder, Frank
Published in British journal of pharmacology (01.07.2002)
Published in British journal of pharmacology (01.07.2002)
Get full text
Journal Article
Abstract P167: CXCR4 Antagonism Is Equally Effective as Sirolimus in Reducing Neointima Formation After Arterial Injury Without Impairing Reendothelialization
Hamesch, Karim, Subramanian, Pallavi, Li, Xiaofeng, Thiemann, Anna, Heyll, Kathrin, Dembowsky, Klaus, Chevalier, Eric, Weber, Christian, Schober, Andreas
Published in Circulation research (09.12.2011)
Published in Circulation research (09.12.2011)
Get full text
Journal Article
Atrial but Not Ventricular Fibrosis in Mice Expressing a Mutant Transforming Growth Factor-β1 Transgene in the Heart
Nakajima, Hidehiro, Nakajima, Hisako O, Salcher, Olga, Dittiè, Andrea S, Dembowsky, Klaus, Jing, Shaoliang, Field, Loren J
Published in Circulation research (17.03.2000)
Published in Circulation research (17.03.2000)
Get full text
Journal Article
Targeting CXCR4, SDF1 and Beta-Adrenergic Receptors In the AML Microenvironment by Novel Antagonist POL6326, G-CSF and Isoproterenol
Chen, Ye, Zeng, Zhihong, Shi, Yuexi, Jacamo, Rodrigo, Ludin, Christian, Dembowsky, Klaus, Frenette, Paul S., Konopleva, Marina, Andreeff, Michael
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
Get full text
Journal Article
Pharmacological actions of a novel NO‐independent guanylyl cyclase stimulator, BAY 41‐8543: in vitro studies
Stasch, Johannes‐Peter, Alonso‐Alija, Cristina, Apeler, Heiner, Dembowsky, Klaus, Feurer, Achim, Minuth, Torsten, Perzborn, Elisabeth, Schramm, Matthias, Straub, Alexander
Published in British journal of pharmacology (01.01.2002)
Published in British journal of pharmacology (01.01.2002)
Get full text
Journal Article