Internalization and desensitization of adenosine receptors
Klaasse, Elisabeth C., IJzerman, Adriaan P., de Grip, Willem J., Beukers, Margot W.
Published in Purinergic signalling (01.03.2008)
Published in Purinergic signalling (01.03.2008)
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N6-Cyclopentyl-2-(3-phenylaminocarbonyltriazene-1-yl)adenosine (TCPA), a Very Selective Agonist with High Affinity for the Human Adenosine A1 Receptor
BEUKERS, Margot W., WANNER, Martin J., VON FRIJTAG DRABBE KüNZEL, Jacobien K., KLAASSE, Elisabeth C., IJZERMAN, Adriaan P., KOOMEN, Gerrit-Jan
Published in Journal of medicinal chemistry (10.04.2003)
Published in Journal of medicinal chemistry (10.04.2003)
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Journal Article
Allosteric modulators of the hERG K+ channel
Yu, Zhiyi, Klaasse, Elisabeth, Heitman, Laura H., IJzerman, Adriaan P.
Published in Toxicology and applied pharmacology (01.01.2014)
Published in Toxicology and applied pharmacology (01.01.2014)
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Removal of Human Ether-à-go-go Related Gene (hERG) K+ Channel Affinity through Rigidity: A Case of Clofilium Analogues
Louvel, Julien, Carvalho, João F. S, Yu, Zhiyi, Soethoudt, Marjolein, Lenselink, Eelke B, Klaasse, Elisabeth, Brussee, Johannes, IJzerman, Adriaan P
Published in Journal of medicinal chemistry (12.12.2013)
Published in Journal of medicinal chemistry (12.12.2013)
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Journal Article
Strategies To Reduce hERG K+ Channel Blockade. Exploring Heteroaromaticity and Rigidity in Novel Pyridine Analogues of Dofetilide
Carvalho, João F. S, Louvel, Julien, Doornbos, Maarten L. J, Klaasse, Elisabeth, Yu, Zhiyi, Brussee, Johannes, IJzerman, Adriaan P
Published in Journal of medicinal chemistry (11.04.2013)
Published in Journal of medicinal chemistry (11.04.2013)
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Journal Article
Understanding of Molecular Substructures that Contribute to hERG K+ Channel Blockade: Synthesis and Biological Evaluation of E-4031 Analogues
Vilums, Maris, Overman, Jeroen, Klaasse, Elisabeth, Scheel, Olaf, Brussee, Johannes, IJzerman, Adriaan P.
Published in ChemMedChem (02.01.2012)
Published in ChemMedChem (02.01.2012)
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Characterization of [H]LUF5834: a novel non-ribose high-affinity agonist radioligand for the adenosine A receptor
Lane, J. Robert, Klaasse, Elisabeth, Lin, Judy, van Bruchem, John, Beukers, Margot W., Ijzerman, Adriaan P.
Published in Biochemical pharmacology (15.10.2010)
Published in Biochemical pharmacology (15.10.2010)
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Characterization of [3H]LUF5834: A novel non-ribose high-affinity agonist radioligand for the adenosine A1 receptor
LANE, J. Robert, KLAASSE, Elisabeth, LIN, Judy, VAN BRUCHEM, John, BEUKERS, Margot W, IJZERMAN, Adriaan P
Published in Biochemical pharmacology (15.10.2010)
Published in Biochemical pharmacology (15.10.2010)
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Journal Article
Characterization of [ 3H]LUF5834: A novel non-ribose high-affinity agonist radioligand for the adenosine A 1 receptor
Lane, J. Robert, Klaasse, Elisabeth, Lin, Judy, van Bruchem, John, Beukers, Margot W., IJzerman, Adriaan P.
Published in Biochemical pharmacology (2010)
Published in Biochemical pharmacology (2010)
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Cover Picture: Understanding of Molecular Substructures that Contribute to hERG K+ Channel Blockade: Synthesis and Biological Evaluation of E-4031 Analogues (ChemMedChem 1/2012)
Vilums, Maris, Overman, Jeroen, Klaasse, Elisabeth, Scheel, Olaf, Brussee, Johannes, IJzerman, Adriaan P.
Published in ChemMedChem (02.01.2012)
Published in ChemMedChem (02.01.2012)
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Journal Article
Exploring Chemical Substructures Essential for hERG K+ Channel Blockade by Synthesis and Biological Evaluation of Dofetilide Analogues
Shagufta, Guo, Dong, Klaasse, Elisabeth, de Vries, Henk, Brussee, Johannes, Nalos, Lukáš, Rook, Martin B., Vos, Marc A., van der Heyden, Marcel A. G., IJzerman, Adriaan P.
Published in ChemMedChem (01.10.2009)
Published in ChemMedChem (01.10.2009)
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Journal Article
Allosteric modulation and constitutive activity of fusion proteins between the adenosine A 1 receptor and different 351Cys-mutated G i α-subunits
Klaasse, Elisabeth, de Ligt, Rianne A.F., Roerink, Sophie F., Lorenzen, Anna, Milligan, Graeme, Leurs, Rob, IJzerman, Ad P.
Published in European journal of pharmacology (2004)
Published in European journal of pharmacology (2004)
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Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi α-subunits
KLAASSE, Elisabeth, DE LIGT, Rianne A. F, ROERINK, Sophie F, LORENZEN, Anna, MILLIGAN, Graeme, LEURS, Rob, IJZERMAN, Ad P
Published in European journal of pharmacology (19.09.2004)
Published in European journal of pharmacology (19.09.2004)
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N 6 -Cyclopentyl-2-(3-phenylaminocarbonyltriazene-1-yl)adenosine (TCPA), a Very Selective Agonist with High Affinity for the Human Adenosine A 1 Receptor
Beukers, Margot W., Wanner, Martin J., Von Frijtag Drabbe Künzel, Jacobien K., Klaasse, Elisabeth C., IJzerman, Adriaan P., Koomen, Gerrit-Jan
Published in Journal of medicinal chemistry (01.04.2003)
Published in Journal of medicinal chemistry (01.04.2003)
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Journal Article
N 6-Cyclopentyl-2-(3-phenylaminocarbonyltriazene-1-yl)adenosine (TCPA), a Very Selective Agonist with High Affinity for the Human Adenosine A1 Receptor
Beukers, Margot W, Wanner, Martin J, Von Frijtag Drabbe Künzel, Jacobien K, Klaasse, Elisabeth C, IJzerman, Adriaan P, Koomen, Gerrit-Jan
Published in Journal of medicinal chemistry (10.04.2003)
Published in Journal of medicinal chemistry (10.04.2003)
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Journal Article