Design and Synthesis of Fluoro Analogues of Vitamin D
Kawagoe, Fumihiro, Mototani, Sayuri, Kittaka, Atsushi
Published in International journal of molecular sciences (01.08.2021)
Published in International journal of molecular sciences (01.08.2021)
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Chiral peptide nucleic acids with a substituent in the N-(2-aminoethy)glycine backbone
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Journal Article
Book Review
The First Convergent Synthesis of 23,23-Difluoro-25-hydroxyvitamin D3 and Its 24-Hydroxy Derivatives: Preliminary Assessment of Biological Activities
Mototani, Sayuri, Kawagoe, Fumihiro, Yasuda, Kaori, Mano, Hiroki, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in Molecules (Basel, Switzerland) (22.08.2022)
Published in Molecules (Basel, Switzerland) (22.08.2022)
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Journal Article
Efficient Stereo-Selective Fluorination on Vitamin D3 Side-Chain Using Electrophilic Fluorination
Kawagoe, Fumihiro, Mototani, Sayuri, Kittaka, Atsushi
Published in Biomolecules (Basel, Switzerland) (01.01.2024)
Published in Biomolecules (Basel, Switzerland) (01.01.2024)
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Journal Article
Stereoselective Synthesis of 24-Fluoro-25-Hydroxyvitamin D3 Analogues and Their Stability to hCYP24A1-Dependent Catabolism
Kawagoe, Fumihiro, Mototani, Sayuri, Yasuda, Kaori, Mano, Hiroki, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in International journal of molecular sciences (01.11.2021)
Published in International journal of molecular sciences (01.11.2021)
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Journal Article
Synthesis of New 26,27-Difluoro- and 26,26,27,27-Tetrafluoro-25-hydroxyvitamin D3: Effects of Terminal Fluorine Atoms on Biological Activity and Half-life
Kawagoe, Fumihiro, Mototani, Sayuri, Yasuda, Kaori, Mano, Hiroki, Takeuchi, Akiko, Saitoh, Hiroshi, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in Chemical & pharmaceutical bulletin (01.09.2023)
Published in Chemical & pharmaceutical bulletin (01.09.2023)
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Journal Article
The Synthesis and Biological Evaluation of D-Ring-Modified Vitamin D Analogues
Kawagoe, Fumihiro, Mototani, Sayuri, Kittaka, Atsushi
Published in Biomolecules (Basel, Switzerland) (04.11.2021)
Published in Biomolecules (Basel, Switzerland) (04.11.2021)
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Journal Article
Novel biosensor using split-luciferase for detecting vitamin D receptor ligands based on the interaction between vitamin D receptor and coactivator
Mano, Hiroki, Takano, Masashi, Ikushiro, Shinichi, Kittaka, Atsushi, Sakaki, Toshiyuki
Published in Biochemical and biophysical research communications (28.10.2018)
Published in Biochemical and biophysical research communications (28.10.2018)
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Journal Article
Development of a highly sensitive in vitro system to detect and discriminate between vitamin D receptor agonists and antagonists based on split-luciferase technique
Mano, Hiroki, Ikushiro, Shinichi, Saito, Nozomi, Kittaka, Atsushi, Sakaki, Toshiyuki
Published in The Journal of steroid biochemistry and molecular biology (01.04.2018)
Published in The Journal of steroid biochemistry and molecular biology (01.04.2018)
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Journal Article
Robust osteogenic efficacy of 2α-heteroarylalkyl vitamin D analogue AH-1 in VDR (R270L) hereditary vitamin D-dependent rickets model rats
Nishikawa, Miyu, Murose, Naruhiro, Mano, Hiroki, Yasuda, Kaori, Isogai, Yasuhiro, Kittaka, Atsushi, Takano, Masashi, Ikushiro, Shinichi, Sakaki, Toshiyuki
Published in Scientific reports (22.07.2022)
Published in Scientific reports (22.07.2022)
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Development of In Vitro and In Vivo Evaluation Systems for Vitamin D Derivatives and Their Application to Drug Discovery
Yasuda, Kaori, Nishikawa, Miyu, Mano, Hiroki, Takano, Masashi, Kittaka, Atsushi, Ikushiro, Shinichi, Sakaki, Toshiyuki
Published in International journal of molecular sciences (31.10.2021)
Published in International journal of molecular sciences (31.10.2021)
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Journal Article
Stereoselective Synthesis of Four Calcitriol Lactone Diastereomers at C23 and C25
Nagata, Akiko, Akagi, Yusuke, Masoud, Shadi Sedghi, Yamanaka, Masahiro, Kittaka, Atsushi, Uesugi, Motonari, Odagi, Minami, Nagasawa, Kazuo
Published in Journal of organic chemistry (21.06.2019)
Published in Journal of organic chemistry (21.06.2019)
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Journal Article
Elucidation of metabolic pathways of 25-hydroxyvitamin D3 mediated by CYP24A1 and CYP3A using Cyp24a1 knockout rats generated by CRISPR/Cas9 system
Yasuda, Kaori, Nishikawa, Miyu, Okamoto, Kairi, Horibe, Kyohei, Mano, Hiroki, Yamaguchi, Mana, Okon, Risa, Nakagawa, Kimie, Tsugawa, Naoko, Okano, Toshio, Kawagoe, Fumihiro, Kittaka, Atsushi, Ikushiro, Shinichi, Sakaki, Toshiyuki
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Synthesis and characterization of PNA oligomers containing preQ1 as a positively charged guanine analogue
Moriya, Shun-suke, Shibasaki, Hatsune, Kohara, Misaki, Kuwata, Keiko, Imamura, Yasutada, Demizu, Yosuke, Kurihara, Masaaki, Kittaka, Atsushi, Sugiyama, Toru
Published in Bioorganic & medicinal chemistry letters (01.05.2021)
Published in Bioorganic & medicinal chemistry letters (01.05.2021)
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Journal Article
Introduction of fluorine atoms to vitamin D3 side-chain and synthesis of 24,24-difluoro-25-hydroxyvitamin D3
Kawagoe, Fumihiro, Mototani, Sayuri, Yasuda, Kaori, Nagasawa, Kazuo, Uesugi, Motonari, Sakaki, Toshiyuki, Kittaka, Atsushi
Published in The Journal of steroid biochemistry and molecular biology (01.12.2019)
Published in The Journal of steroid biochemistry and molecular biology (01.12.2019)
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Journal Article
Ligand chirality can affect histidine protonation of vitamin-D receptor: ab initio molecular orbital calculations in water
Terauchi, Yuta, Suzuki, Rie, Takeda, Ryosuke, Kobayashi, Ittetsu, Kittaka, Atsushi, Takimoto-Kamimura, Midori, Kurita, Noriyuki
Published in The Journal of steroid biochemistry and molecular biology (01.02.2019)
Published in The Journal of steroid biochemistry and molecular biology (01.02.2019)
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Journal Article
Proposal of novel inhibitors for vitamin-D receptor: Molecular docking, molecular mechanics and ab initio molecular orbital simulations
Nakamura, Shunya, Saito, Ryosuke, Yamamoto, Shohei, Terauchi, Yuta, Kittaka, Atsushi, Takimoto-Kamimura, Midori, Kurita, Noriyuki
Published in Biophysical chemistry (01.03.2021)
Published in Biophysical chemistry (01.03.2021)
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