Mirogabalin inhibits scratching behavior of spontaneous model mouse of atopic dermatitis
Matsuda, Kosuke, Kitano, Yutaka, Sawahata, Masahito, Kume, Toshiaki, Uta, Daisuke
Published in Frontiers in pharmacology (26.06.2024)
Published in Frontiers in pharmacology (26.06.2024)
Get full text
Journal Article
Voltage-gated calcium channel subunit α2δ-1 in spinal dorsal horn neurons contributes to aberrant excitatory synaptic transmission and mechanical hypersensitivity after peripheral nerve injury
Koga, Keisuke, Kobayashi, Kenta, Tsuda, Makoto, Kubota, Kazufumi, Kitano, Yutaka, Furue, Hidemasa
Published in Frontiers in molecular neuroscience (23.03.2023)
Published in Frontiers in molecular neuroscience (23.03.2023)
Get full text
Journal Article
Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit
Kozai, Daisuke, Numoto, Nobutaka, Nishikawa, Kouki, Kamegawa, Akiko, Kawasaki, Shohei, Hiroaki, Yoko, Irie, Katsumasa, Oshima, Atsunori, Hanzawa, Hiroyuki, Shimada, Kousei, Kitano, Yutaka, Fujiyoshi, Yoshinori
Published in Journal of molecular biology (15.05.2023)
Published in Journal of molecular biology (15.05.2023)
Get full text
Journal Article
Analgesic effects of mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, in experimental animal models of fibromyalgia
Saeki, Kensuke, Yasuda, Shun-ichi, Kato, Masami, Kano, Mayumi, Domon, Yuki, Arakawa, Naohisa, Kitano, Yutaka
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.06.2019)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.06.2019)
Get full text
Journal Article
Mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, improves cognitive impairments in repeated intramuscular acidic saline injection model rats, an experimental model of fibromyalgia
Murasawa, Hiroyasu, Pawlak, Akiko, Kobayashi, Hiroyuki, Saeki, Kensuke, Yasuda, Shun-ichi, Kitano, Yutaka
Published in Biomedicine & pharmacotherapy (01.07.2021)
Published in Biomedicine & pharmacotherapy (01.07.2021)
Get full text
Journal Article
Discovery of a Novel Class of State-Dependent NaV1.7 Inhibitors for the Treatment of Neuropathic Pain
Tanaka, Kyosuke, Kobayashi, Hiroyuki, Suzuki, Sayaka, Shibuya, Satoshi, Kimoto, Hiroko, Domon, Yuki, Kubota, Kazufumi, Kitano, Yutaka, Yokoyama, Tomihisa, Shimizugawa, Akiko, Koishi, Ryuta, Fujiwara, Chie, Asano, Daigo, Shinozuka, Tsuyoshi
Published in Chemical & pharmaceutical bulletin (01.07.2020)
Published in Chemical & pharmaceutical bulletin (01.07.2020)
Get full text
Journal Article
Discovery of a Novel Class of State-Dependent Na(V)1.7 Inhibitors for the Treatment of Neuropathic Pain
Tanaka, Kyosuke, Kobayashi, Hiroyuki, Suzuki, Sayaka, Shibuya, Satoshi, Kimoto, Hiroko, Domon, Yuki, Kubota, Kazufumi, Kitano, Yutaka, Yokoyama, Tomihisa, Shimizugawa, Akiko, Koishi, Ryuta, Fujiwara, Chie, Asano, Daigo, Shinozuka, Tsuyoshi
Published in Chemical & pharmaceutical bulletin (01.07.2020)
Published in Chemical & pharmaceutical bulletin (01.07.2020)
Get full text
Journal Article
Infantile Pain Episodes Associated with Novel Nav1.9 Mutations in Familial Episodic Pain Syndrome in Japanese Families
Okuda, Hiroko, Noguchi, Atsuko, Kobayashi, Hatasu, Kondo, Daiki, Harada, Kouji H, Youssefian, Shohab, Shioi, Hirotomo, Kabata, Risako, Domon, Yuki, Kubota, Kazufumi, Kitano, Yutaka, Takayama, Yasunori, Hitomi, Toshiaki, Ohno, Kousaku, Saito, Yoshiaki, Asano, Takeshi, Tominaga, Makoto, Takahashi, Tsutomu, Koizumi, Akio
Published in PloS one (25.05.2016)
Published in PloS one (25.05.2016)
Get full text
Journal Article
Binding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium Channels
Domon, Yuki, Arakawa, Naohisa, Inoue, Tatsuya, Matsuda, Fumihiko, Takahashi, Makoto, Yamamura, Naotoshi, Kai, Kiyonori, Kitano, Yutaka
Published in The Journal of pharmacology and experimental therapeutics (01.06.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2018)
Get full text
Journal Article
Discovery of (phenoxy-2-hydroxypropyl)piperidines as a novel class of voltage-gated sodium channel 1.7 inhibitors
Suzuki, Sayaka, Kuroda, Takeshi, Kimoto, Hiroko, Domon, Yuki, Kubota, Kazufumi, Kitano, Yutaka, Yokoyama, Tomihisa, Shimizugawa, Akiko, Sugita, Ryusuke, Koishi, Ryuta, Asano, Daigo, Tamaki, Kazuhiko, Shinozuka, Tsuyoshi, Kobayashi, Hiroyuki
Published in Bioorganic & medicinal chemistry letters (15.11.2015)
Published in Bioorganic & medicinal chemistry letters (15.11.2015)
Get full text
Journal Article
DY-9760e, a Calmodulin Antagonist, Reduces Brain Damage after Permanent Focal Cerebral Ischemia in Cats
Sugimura, Masunobu, Takamori, Hideo, Fukushi, Hiromichi, Kitano, Yutaka, Kanazawa, Yoshito, Shirasaki, Yasufumi
Published in Biological & Pharmaceutical Bulletin (01.04.2005)
Published in Biological & Pharmaceutical Bulletin (01.04.2005)
Get full text
Journal Article
Effects of Nefiracetam, a Novel Pyrrolidone‐type Nootropic Agent, on the Amygdala‐kindled Seizures in Rats
Kitano, Yutaka, Komiyama, Chika, Makino, Mitsuhiro, Kasai, Yoshio, Takasuna, Kiyoshi, Kinoshita, Masakazu, Yamazaki, Osamu, Takazawa, Akira, Yamauchi, Toshio, Sakurada, Shinobu
Published in Epilepsia (Copenhagen) (01.10.2005)
Published in Epilepsia (Copenhagen) (01.10.2005)
Get full text
Journal Article
Anxiolytic effects of the novel [alpha].sub.2[delta] ligand mirogabalin in a rat model of chronic constriction injury, an experimental model of neuropathic pain
Murasawa, Hiroyasu, Kobayashi, Hiroyuki, Saeki, Kensuke, Kitano, Yutaka
Published in Psychopharmacology (01.01.2020)
Published in Psychopharmacology (01.01.2020)
Get full text
Journal Article
The Novel Gabapentinoid Mirogabalin Prevents Upregulation of α2δ-1 Subunit of Voltage-Gated Calcium Channels in Spinal Dorsal Horn in a Rat Model of Spinal Nerve Ligation
Domon, Yuki, Kobayashi, Naoko, Kubota, Kazufumi, Kitano, Yutaka, Ueki, Hideaki, Shimojo, Yumiko, Ishikawa, Kayoko, Ofune, Yuka
Published in Drug research (01.01.2023)
Published in Drug research (01.01.2023)
Get full text
Journal Article