The role of ASXL1 in hematopoiesis and myeloid malignancies
Asada, Shuhei, Fujino, Takeshi, Goyama, Susumu, Kitamura, Toshio
Published in Cellular and molecular life sciences : CMLS (01.07.2019)
Published in Cellular and molecular life sciences : CMLS (01.07.2019)
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Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
Nagase, Reina, Inoue, Daichi, Pastore, Alessandro, Fujino, Takeshi, Hou, Hsin-An, Yamasaki, Norimasa, Goyama, Susumu, Saika, Makoto, Kanai, Akinori, Sera, Yasuyuki, Horikawa, Sayuri, Ota, Yasunori, Asada, Shuhei, Hayashi, Yasutaka, Kawabata, Kimihito Cojin, Takeda, Reina, Tien, Hwei-Fang, Honda, Hiroaki, Abdel-Wahab, Omar, Kitamura, Toshio
Published in The Journal of experimental medicine (04.06.2018)
Published in The Journal of experimental medicine (04.06.2018)
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Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway
Fujino, Takeshi, Goyama, Susumu, Sugiura, Yuki, Inoue, Daichi, Asada, Shuhei, Yamasaki, Satoshi, Matsumoto, Akiko, Yamaguchi, Kiyoshi, Isobe, Yumiko, Tsuchiya, Akiho, Shikata, Shiori, Sato, Naru, Morinaga, Hironobu, Fukuyama, Tomofusa, Tanaka, Yosuke, Fukushima, Tsuyoshi, Takeda, Reina, Yamamoto, Keita, Honda, Hiroaki, Nishimura, Emi K., Furukawa, Yoichi, Shibata, Tatsuhiro, Abdel-Wahab, Omar, Suematsu, Makoto, Kitamura, Toshio
Published in Nature communications (23.03.2021)
Published in Nature communications (23.03.2021)
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UBC9 inhibits myeloid differentiation in collaboration with AML1-MTG8
Fukuyama, Tomofusa, Kitamura, Toshio, Kozu, Tomoko
Published in International journal of hematology (01.05.2022)
Published in International journal of hematology (01.05.2022)
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Identification of Tim4 as a phosphatidylserine receptor
Uchiyama, Yasuo, Koike, Masato, Kitamura, Toshio, Nagata, Shigekazu, Miyanishi, Masanori, Tada, Kazutoshi
Published in Nature (15.11.2007)
Published in Nature (15.11.2007)
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Exit from germinal center to become quiescent memory B cells depends on metabolic reprograming and provision of a survival signal
Inoue, Takeshi, Shinnakasu, Ryo, Kawai, Chie, Ise, Wataru, Kawakami, Eiryo, Sax, Nicolas, Oki, Toshihiko, Kitamura, Toshio, Yamashita, Kazuo, Fukuyama, Hidehiro, Kurosaki, Tomohiro
Published in The Journal of experimental medicine (04.01.2021)
Published in The Journal of experimental medicine (04.01.2021)
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Induction of human cardiomyocyte-like cells from fibroblasts by defined factors
Wada, Rie, Muraoka, Naoto, Inagawa, Kohei, Yamakawa, Hiroyuki, Miyamoto, Kazutaka, Sadahiro, Taketaro, Umei, Tomohiko, Kaneda, Ruri, Suzuki, Tomoyuki, Kamiya, Kaichiro, Tohyama, Shugo, Yuasa, Shinsuke, Kokaji, Kiyokazu, Aeba, Ryo, Yozu, Ryohei, Yamagishi, Hiroyuki, Kitamura, Toshio, Fukuda, Keiichi, Ieda, Masaki
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2013)
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PD-L1/L2 protein levels rapidly increase on monocytes via trogocytosis from tumor cells in classical Hodgkin lymphoma
Kawashima, Masaharu, Carreras, Joaquim, Higuchi, Hiroshi, Kotaki, Ryutaro, Hoshina, Takahiro, Okuyama, Kazuki, Suzuki, Naoto, Kakizaki, Masatoshi, Miyatake, Yuji, Ando, Kiyoshi, Nakayama, Masafumi, Umezu, Shinjiro, Horie, Ryouichi, Higuchi, Yuriko, Katagiri, Koko, Goyama, Susumu, Kitamura, Toshio, Chamoto, Kenji, Yano, Shingo, Nakamura, Naoya, Kotani, Ai
Published in Leukemia (01.09.2020)
Published in Leukemia (01.09.2020)
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Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML
Oki, Toshihiko, Mercier, Francois, Kato, Hiroki, Jung, Yookyung, McDonald, Thomas O., Spencer, Joel A., Mazzola, Michael C., van Gastel, Nick, Lin, Charles P., Michor, Franziska, Kitamura, Toshio, Scadden, David T.
Published in Nature communications (11.01.2021)
Published in Nature communications (11.01.2021)
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CHIP‐associated mutant ASXL1 in blood cells promotes solid tumor progression
Liu, Xiaoxiao, Sato, Naru, Shimosato, Yuko, Wang, Teh‐Wei, Denda, Tamami, Chang, Yu‐Hsuan, Yabushita, Tomohiro, Fujino, Takeshi, Asada, Shuhei, Tanaka, Yosuke, Fukuyama, Tomofusa, Enomoto, Yutaka, Ota, Yasunori, Sakamoto, Takeharu, Kitamura, Toshio, Goyama, Susumu
Published in Cancer science (01.04.2022)
Published in Cancer science (01.04.2022)
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Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis
Asada, Shuhei, Goyama, Susumu, Inoue, Daichi, Shikata, Shiori, Takeda, Reina, Fukushima, Tsuyoshi, Yonezawa, Taishi, Fujino, Takeshi, Hayashi, Yasutaka, Kawabata, Kimihito Cojin, Fukuyama, Tomofusa, Tanaka, Yosuke, Yokoyama, Akihiko, Yamazaki, Satoshi, Kozuka-Hata, Hiroko, Oyama, Masaaki, Kojima, Shinya, Kawazu, Masahito, Mano, Hiroyuki, Kitamura, Toshio
Published in Nature communications (16.07.2018)
Published in Nature communications (16.07.2018)
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Role of exosomes as a proinflammatory mediator in the development of EBV-associated lymphoma
Higuchi, Hiroshi, Yamakawa, Natsuko, Imadome, Ken-Ichi, Yahata, Takashi, Kotaki, Ryutaro, Ogata, Jun, Kakizaki, Masatoshi, Fujita, Koji, Lu, Jun, Yokoyama, Kazuaki, Okuyama, Kazuki, Sato, Ai, Takamatsu, Masako, Kurosaki, Natsumi, Alba, Syakira Mohamad, Azhim, Azran, Horie, Ryouichi, Watanabe, Toshiki, Kitamura, Toshio, Ando, Kiyoshi, Kashiwagi, Takao, Matsui, Toshimitsu, Okamoto, Akinao, Handa, Hiroshi, Kuroda, Masahiko, Nakamura, Naoya, Kotani, Ai
Published in Blood (07.06.2018)
Published in Blood (07.06.2018)
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Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors
Tanaka, Yosuke, Takeda, Reina, Fukushima, Tsuyoshi, Mikami, Keiko, Tsuchiya, Shun, Tamura, Moe, Adachi, Keito, Umemoto, Terumasa, Asada, Shuhei, Watanabe, Naoki, Morishita, Soji, Imai, Misa, Nagata, Masayoshi, Araki, Marito, Takizawa, Hitoshi, Fukuyama, Tomofusa, Lamagna, Chrystelle, Masuda, Esteban S., Ito, Ryoji, Goyama, Susumu, Komatsu, Norio, Takaku, Tomoiku, Kitamura, Toshio
Published in Nature communications (12.01.2022)
Published in Nature communications (12.01.2022)
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Genetic regulation of the RUNX transcription factor family has antitumor effects
Morita, Ken, Suzuki, Kensho, Maeda, Shintaro, Matsuo, Akihiko, Mitsuda, Yoshihide, Tokushige, Chieko, Kashiwazaki, Gengo, Taniguchi, Junichi, Maeda, Rina, Noura, Mina, Hirata, Masahiro, Kataoka, Tatsuki, Yano, Ayaka, Yamada, Yoshimi, Kiyose, Hiroki, Tokumasu, Mayu, Matsuo, Hidemasa, Tanaka, Sunao, Okuno, Yasushi, Muto, Manabu, Naka, Kazuhito, Ito, Kosei, Kitamura, Toshio, Kaneda, Yasufumi, Liu, Paul P, Bando, Toshikazu, Adachi, Souichi, Sugiyama, Hiroshi, Kamikubo, Yasuhiko
Published in The Journal of clinical investigation (30.06.2017)
Published in The Journal of clinical investigation (30.06.2017)
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Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
Miyamoto, Ryo, Okuda, Hiroshi, Kanai, Akinori, Takahashi, Satoshi, Kawamura, Takeshi, Matsui, Hirotaka, Kitamura, Toshio, Kitabayashi, Issay, Inaba, Toshiya, Yokoyama, Akihiko
Published in Cell reports (Cambridge) (29.09.2020)
Published in Cell reports (Cambridge) (29.09.2020)
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