Suppression of the Epithelial–Mesenchymal Transition and Maintenance of the Liver Functions in Primary Hepatocytes through Dispersion Culture within a Dome-Shaped Collagen Matrix
Tonooka, Yoshino, Takaku, Tomoyuki, Toyoshima, Manabu, Takahashi, Yasuhiko, Kitamoto, Sachiko
Published in Biological & pharmaceutical bulletin (01.07.2024)
Published in Biological & pharmaceutical bulletin (01.07.2024)
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Comparative hepatotoxicity of a herbicide, epyrifenacil, in humans and rodents by comparing the dynamics and kinetics of its causal metabolite
Matsunaga, Kohei, Fukunaga, Satoki, Abe, Jun, Takeuchi, Hayato, Kitamoto, Sachiko, Tomigahara, Yoshitaka
Published in Journal of Pesticide Science (20.11.2021)
Published in Journal of Pesticide Science (20.11.2021)
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Lack of human relevance for rat developmental toxicity of flumioxazin is revealed by comparative heme synthesis assay using embryonic erythroid cells derived from human and rat pluripotent stem cells
Asano, Koji, Takahashi, Yasuhiko, Ueno, Manako, Fukuda, Takako, Otani, Mitsuhiro, Kitamoto, Sachiko, Tomigahara, Yoshitaka
Published in Journal of toxicological sciences (01.01.2022)
Published in Journal of toxicological sciences (01.01.2022)
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Elucidation of the species differences of epyrifenacil-induced hepatotoxicity between mice and humans by mass spectrometry imaging analysis in chimeric mice with humanized liver
Matsunaga, Kohei, Abe, Jun, Ogata, Keiko, Fukunaga, Satoki, Kitamoto, Sachiko
Published in Journal of toxicological sciences (2021)
Published in Journal of toxicological sciences (2021)
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Identification of the organic anion transporting polypeptides responsible for the hepatic uptake of the major metabolite of epyrifenacil, S‐3100‐CA, in mice
Sakurai, Kengo, Kuroda, Tomohiro, Abe, Jun, Toda, Hiroshi, Kitamoto, Sachiko
Published in Pharmacology research & perspectives (01.10.2021)
Published in Pharmacology research & perspectives (01.10.2021)
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JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results
Uno, Yoshifumi, Kojima, Hajime, Omori, Takashi, Corvi, Raffaella, Honma, Masamistu, Schechtman, Leonard M., Tice, Raymond R., Beevers, Carol, Boeck, Marlies De, Burlinson, Brian, Hobbs, Cheryl A., Kitamoto, Sachiko, Kraynak, Andrew R., McNamee, James, Nakagawa, Yuzuki, Pant, Kamala, Plappert-Helbig, Ulla, Priestley, Catherine, Takasawa, Hironao, Wada, Kunio, Wirnitzer, Uta, Asano, Norihide, Escobar, Patricia A., Lovell, David, Morita, Takeshi, Nakajima, Madoka, Ohno, Yasuo, Hayashi, Makoto
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.07.2015)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.07.2015)
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Increased susceptibility to hepatocarcinogenicity of Nrf2‐deficient mice exposed to 2‐amino‐3‐methylimidazo[4,5‐f]quinoline
Kitamura, Yasuki, Umemura, Takashi, Kanki, Keita, Kodama, Yukio, Kitamoto, Sachiko, Saito, Koichi, Itoh, Ken, Yamamoto, Masayuki, Masegi, Toshiaki, Nishikawa, Akiyoshi, Hirose, Masao
Published in Cancer science (01.01.2007)
Published in Cancer science (01.01.2007)
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KOJIC ACID -ABSENCE OF TUMOR-INITIATING ACTIVITY IN RAT LIVER, AND OF CARCINOGENIC AND PHOTO-GENOTOXIC POTENTIAL IN MOUSE SKIN
HIGA, Yoshitaka, KAWABE, Mayumi, NABAE, Kyoko, TODA, Yosuke, KITAMOTO, Sachiko, HARA, Takumi, TANAKA, Noriho, KARIYA, Kimio, TAKAHASHI, Michihito
Published in Journal of toxicological sciences (2007)
Published in Journal of toxicological sciences (2007)
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Comparison of cytokine profiles in bronchoalveolar lavage fluid of mice exposed to respiratory and contact sensitizers
Mori, Takashi, Tanimoto, Yoshiharu, Ota, Mika, Masakado, Takaomi, Kitamoto, Sachiko, Saito, Koichi, Isobe, Naohiko, Kaneko, Hideo
Published in Journal of toxicological sciences (2012)
Published in Journal of toxicological sciences (2012)
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Prediction of the human pharmacokinetics of epyrifenacil and its major metabolite, S-3100-CA, by a physiologically based pharmacokinetic modeling using chimeric mice with humanized liver
Hirasawa, Kota, Abe, Jun, Nagahori, Hirohisa, Kitamoto, Sachiko
Published in Toxicology and applied pharmacology (15.03.2022)
Published in Toxicology and applied pharmacology (15.03.2022)
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Journal Article
Club Cells Are the Primary Target for Permethrin-Induced Mouse Lung Tumor Formation
Ogata, Keiko, Liu, Yang, Ohara, Ayako, Kawamoto, Kensuke, Kondo, Miwa, Kobayashi, Kumiko, Fukuda, Takako, Asano, Hiroyuki, Kitamoto, Sachiko, Lake, Brian G, Cohen, Samuel M, Yamada, Tomoya
Published in Toxicological sciences (27.10.2021)
Published in Toxicological sciences (27.10.2021)
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Assessment of the performance of the Ames MPF™ assay: A multicenter collaborative study with six coded chemicals
Spiliotopoulos, Dimitrios, Koelbert, Cécile, Audebert, Marc, Barisch, Ilona, Bellet, Deborah, Constans, Mathilde, Czich, Andreas, Finot, Francis, Gervais, Véronique, Khoury, Laure, Kirchnawy, Christian, Kitamoto, Sachiko, Le Tesson, Audrey, Malesic, Laure, Matsuyama, Ryoko, Mayrhofer, Elisa, Mouche, Isabelle, Preikschat, Birgit, Prielinger, Lukas, Rainer, Bernhard, Roblin, Clémence, Wäse, Kerstin
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.01.2024)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.01.2024)
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Journal Article
Comparative hepatotoxicity of a herbicide, epyrifenacil, in humans and rodents by comparing the dynamics and kinetics of its causal metabolite
Matsunaga, Kohei, Fukunaga, Satoki, Abe, Jun, Takeuchi, Hayato, Kitamoto, Sachiko, Tomigahara, Yoshitaka
Published in Journal of Pesticide Science (2021)
Published in Journal of Pesticide Science (2021)
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Journal Article
Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT)
Speit, Günter, Kojima, Hajime, Burlinson, Brian, Collins, Andrew R., Kasper, Peter, Plappert-Helbig, Ulla, Uno, Yoshifumi, Vasquez, Marie, Beevers, Carol, De Boeck, Marlies, Escobar, Patricia A., Kitamoto, Sachiko, Pant, Kamala, Pfuhler, Stefan, Tanaka, Jin, Levy, Dan D.
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.05.2015)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.05.2015)
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Genotoxicity evaluation of benzene, di(2-ethylhexyl) phthalate, and trisodium ethylenediamine tetraacetic acid monohydrate using a combined rat comet/micronucleus assays
Kitamoto, Sachiko, Matsuyama, Ryoko, Uematsu, Yasuaki, Ogata, Keiko, Ota, Mika, Yamada, Toru, Miyata, Kaori, Kimura, Juki, Funabashi, Hitoshi, Saito, Koichi
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.07.2015)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.07.2015)
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Generation and purification of ACTH-secreting hPSC-derived pituitary cells for effective transplantation
Taga, Shiori, Suga, Hidetaka, Nakano, Tokushige, Kuwahara, Atsushi, Inoshita, Naoko, Kodani, Yu, Nagasaki, Hiroshi, Sato, Yoshitaka, Tsumura, Yusuke, Sakakibara, Mayu, Soen, Mika, Miwata, Tsutomu, Ozaki, Hajime, Kano, Mayuko, Watari, Kenji, Ikeda, Atsushi, Yamanaka, Mitsugu, Takahashi, Yasuhiko, Kitamoto, Sachiko, Kawaguchi, Yohei, Miyata, Takashi, Kobayashi, Tomoko, Sugiyama, Mariko, Onoue, Takeshi, Yasuda, Yoshinori, Hagiwara, Daisuke, Iwama, Shintaro, Tomigahara, Yoshitaka, Kimura, Toru, Arima, Hiroshi
Published in Stem cell reports (08.08.2023)
Published in Stem cell reports (08.08.2023)
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