A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1
Das, Debanu, Duncton, Matthew A J, Georgiadis, Taxiarchis M, Pellicena, Patricia, Clark, Jennifer, Sobol, Robert W, Georgiadis, Millie M, King-Underwood, John, Jobes, David V, Chang, Caleb, Gao, Yang, Deacon, Ashley M, Wilson, 3rd, David M
Published in International journal of molecular sciences (01.12.2023)
Published in International journal of molecular sciences (01.12.2023)
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조절제로서의 테트라하이드로피리도피리미딘 유도체
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Year of Publication 04.05.2021
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Year of Publication 04.05.2021
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P38 MAP 1--3-4-2--4--1- 1-PYRAZOLYL-3-4-2-ANILINOPYRIMIDIN-4-YLOXY NAPTHTHALEN-1-YL UREAS AS P38 MAP KINASE INHIBITORS
KING UNDERWOOD JOHN, FILLIERS WALTER, BROECKX RUDY, LONGSHAW ALISTAIR IAN, ITO KAZUHIRO, CHARRON CATHERINE ELISABETH, COPMANS ALEX, ONIONS STUART THOMAS
Year of Publication 03.07.2019
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Year of Publication 03.07.2019
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AROMATIC HETEROCYCLIC COMPOUNDS AS ANTIINFLAMMATORY COMPOUNDS
KING UNDERWOOD JOHN, VENABLE JENNIFER DIANE, FORDYCE EUAN ALEXANDER FRASER, LONGSHAW ALISTAIR IAN, ONIONS STUART THOMAS
Year of Publication 06.10.2016
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Year of Publication 06.10.2016
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3 -43- QUINAZOLIN-4 3H -ONE DERIVATIVES USED AS PI3 KINASE INHIBITORS
KING UNDERWOOD JOHN, MURRAY PETER JOHN, HARDY GEORGE, BROWN CHRISTOPHER JOHN, ITO KAZUHIRO, BROOKFIELD FREDERICK ARTHUR
Year of Publication 23.12.2013
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Year of Publication 23.12.2013
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In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection
Colley, Thomas, Alanio, Alexandre, Kelly, Steven L, Sehra, Gurpreet, Kizawa, Yasuo, Warrilow, Andrew G S, Parker, Josie E, Kelly, Diane E, Kimura, Genki, Anderson-Dring, Lauren, Nakaoki, Takahiro, Sunose, Mihiro, Onions, Stuart, Crepin, Damien, Lagasse, Franz, Crittall, Matthew, Shannon, Jonathan, Cooke, Michael, Bretagne, Stéphane, King-Underwood, John, Murray, John, Ito, Kazuhiro, Strong, Pete, Rapeport, Garth
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Published in Antimicrobial agents and chemotherapy (01.05.2017)
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1-PYRAZOLYL-3-(4-((2-ANILINOPYRIMIDIN-4-YL)OXY) NAPTHTHALEN-1-YL) UREAS AS P38 MAP KINASE INHIBITORS
KING UNDERWOOD JOHN, FILLIERS WALTER, BROECKX RUDY, LONGSHAW ALISTAIR IAN, ITO KAZUHIRO, CHARRON CATHERINE ELISABETH, COPMANS ALEX, ONIONS STUART THOMAS
Year of Publication 18.06.2014
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Year of Publication 18.06.2014
Patent
Compouds
KING UNDERWOOD JOHN, MURRAY PETER JOHN, HARDY GEORGE, BROWN CHRISTOPHER JOHN, ITO KAZUHIRO, BROOKFIELD FREDERICK ARTHUR
Year of Publication 16.10.2012
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Year of Publication 16.10.2012
Patent
PYRAZOLYL-UREAS AS KINASE INHIBITORS
CARIOU CLAIRE ANNE MARIE, KING UNDERWOOD JOHN, FYFE MATTHEW COLIN THOR, HAMZA DANIEL, WATSON HAYLEY TEGAN ANGELA, FORDYCE EUAN ALEXANDER FRASER, THOM STEPHEN MALCOLM, MURRAY PETER JOHN, CHARRON CATHERINE ELISABETH, ITO KAZUHIRO, ONIONS STUART THOMAS, WILLIAMS JONATHAN GARETH
Year of Publication 27.05.2015
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Year of Publication 27.05.2015
Patent
In Vitro and In Vivo Efficacy of a Novel and Long-Acting Fungicidal Azole, PC1244, on Aspergillus fumigatus Infection
Colley, Thomas, Sehra, Gurpreet, Chowdhary, Anuradha, Alanio, Alexandre, Kelly, Steven L, Kizawa, Yasuo, Armstrong-James, Darius, Fisher, Matthew C, Warrilow, Andrew G S, Parker, Josie E, Kelly, Diane E, Kimura, Genki, Nishimoto, Yuki, Sunose, Mihiro, Onions, Stuart, Crepin, Damien, Lagasse, Franz, Crittall, Matthew, Shannon, Jonathan, McConville, Matthew, King-Underwood, John, Naylor, Alan, Bretagne, Stéphane, Murray, John, Ito, Kazuhiro, Strong, Pete, Rapeport, Garth
Published in Antimicrobial agents and chemotherapy (01.05.2018)
Published in Antimicrobial agents and chemotherapy (01.05.2018)
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Synthesis and Activity of a Novel Autotaxin Inhibitor–Icodextrin Conjugate
Fisher, Natalie, Edwards, Michael G, Hemming, Ryan, Allin, Steven M, Wallis, John D, Bulman Page, Philip C, Mckenzie, Michael J, Jones, Stefanie M, Elsegood, Mark R. J, King-Underwood, John, Richardson, Alan
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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Discovery of Narrow Spectrum Kinase Inhibitors: New Therapeutic Agents for the Treatment of COPD and Steroid-Resistant Asthma
Onions, Stuart T, Ito, Kazuhiro, Charron, Catherine E, Brown, Richard J, Colucci, Marie, Frickel, Fritz, Hardy, George, Joly, Kevin, King-Underwood, John, Kizawa, Yasuo, Knowles, Ian, Murray, P. John, Novak, Andrew, Rani, Anjna, Rapeport, Garth, Smith, Alun, Strong, Peter, Taddei, David M, Williams, Jonathan G
Published in Journal of medicinal chemistry (10.03.2016)
Published in Journal of medicinal chemistry (10.03.2016)
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P38 MAP KINASE INHIBITORS
KING UNDERWOOD JOHN, STRONG PETER, MURRAY PETER JOHN, RAPEPORT WILLIAM GARTH, ITO KAZUHIRO, ONIONS STUART, CHARRON CATHERINE ELISABETH, WILLIAMS JONATHAN GARETH
Year of Publication 17.01.2012
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Year of Publication 17.01.2012
Patent
Discovery of novel benzothienoazepine derivatives as potent inhibitors of respiratory syncytial virus
Fordyce, Euan A.F., Brookes, Daniel W., Lise-Ciana, Claire, Coates, Matthew S., Hunt, S. Fraser, Ito, Kazuhiro, King-Underwood, John, Onions, Stuart T., Parra, Guillaume F., Rapeport, Garth, Sherbukhin, Vladimir, Stockwell, Jennifer A., Strong, Peter, Thomas, Jennifer C., Murray, John
Published in Bioorganic & medicinal chemistry letters (15.05.2017)
Published in Bioorganic & medicinal chemistry letters (15.05.2017)
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P38 MAP KINASE INHIBITORS
KING UNDERWOOD JOHN, STRONG PETER, MURRAY PETER JOHN, RAPEPORT WILLIAM GARTH, ITO KAZUHIRO, CHARRON CATHERINE ELISABETH, ONIONS STUART THOMAS, JOLY KEVIN, WILLIAMS JONATHAN GARETH
Year of Publication 19.08.2011
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Year of Publication 19.08.2011
Patent
P38 MAP KINASE INHIBITORS
KING UNDERWOOD JOHN, STRONG PETER, MURRAY PETER JOHN, RAPEPORT WILLIAM GARTH, ITO KAZUHIRO, CHARRON CATHERINE ELISABETH, ONIONS STUART THOMAS, WILLIAMS JONATHAN GARETH
Year of Publication 15.06.2011
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Year of Publication 15.06.2011
Patent
Conformationally restricted benzothienoazepine respiratory syncytial virus inhibitors: their synthesis, structural analysis and biological activitiesElectronic supplementary information (ESI) available. See DOI: 10.1039/c8md00033f
Fordyce, Euan A. F, Fraser Hunt, S, Crepin, Damien, Onions, Stuart T, Parra, Guillaume F, Sleigh, Chris J, King-Underwood, John, Finch, Harry, Murray, John
Year of Publication 20.03.2018
Year of Publication 20.03.2018
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Conformationally restricted benzothienoazepine respiratory syncytial virus inhibitors: their synthesis, structural analysis and biological activities† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00033f
Fordyce, Euan A. F., Fraser Hunt, S., Crepin, Damien, Onions, Stuart T., Parra, Guillaume F., Sleigh, Chris J., King-Underwood, John, Finch, Harry, Murray, John
Published in MedChemComm (20.02.2018)
Published in MedChemComm (20.02.2018)
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