Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes
Camunas-Soler, Joan, Dai, Xiao-Qing, Hang, Yan, Bautista, Austin, Lyon, James, Suzuki, Kunimasa, Kim, Seung K., Quake, Stephen R., MacDonald, Patrick E.
Published in Cell metabolism (05.05.2020)
Published in Cell metabolism (05.05.2020)
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A genetic strategy to measure insulin signaling regulation and physiology in Drosophila
Tsao, Deborah D, Chang, Kathleen R, Kockel, Lutz, Park, Sangbin, Kim, Seung K
Published in PLoS genetics (02.02.2023)
Published in PLoS genetics (02.02.2023)
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Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function
Arda, H. Efsun, Li, Lingyu, Tsai, Jennifer, Torre, Eduardo A., Rosli, Yenny, Peiris, Heshan, Spitale, Robert C., Dai, Chunhua, Gu, Xueying, Qu, Kun, Wang, Pei, Wang, Jing, Grompe, Markus, Scharfmann, Raphael, Snyder, Michael S., Bottino, Rita, Powers, Alvin C., Chang, Howard Y., Kim, Seung K.
Published in Cell metabolism (10.05.2016)
Published in Cell metabolism (10.05.2016)
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Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
Wong, David J, Chang, Howard Y, Hung, Tiffany, Wang, Yulei, Lin, Michael F, Koegel, Ashley K, Kotake, Yojiro, Grant, Gavin D, Horlings, Hugo M, Shah, Nilay, Umbricht, Christopher, Wang, Pei, Wang, Yu, Kong, Benjamin, Langerød, Anita, Børresen-Dale, Anne-Lise, Kim, Seung K, van de Vijver, Marc, Sukumar, Saraswati, Whitfield, Michael L, Kellis, Manolis, Xiong, Yue
Published in Nature genetics (01.07.2011)
Published in Nature genetics (01.07.2011)
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Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing
Chiou, Shin-Heng, Winters, Ian P, Wang, Jing, Naranjo, Santiago, Dudgeon, Crissy, Tamburini, Fiona B, Brady, Jennifer J, Yang, Dian, Grüner, Barbara M, Chuang, Chen-Hua, Caswell, Deborah R, Zeng, Hong, Chu, Pauline, Kim, Grace E, Carpizo, Darren R, Kim, Seung K, Winslow, Monte M
Published in Genes & development (15.07.2015)
Published in Genes & development (15.07.2015)
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Suppression of Insulin Production and Secretion by a Decretin Hormone
Alfa, Ronald W., Park, Sangbin, Skelly, Kathleen-Rose, Poffenberger, Gregory, Jain, Nimit, Gu, Xueying, Kockel, Lutz, Wang, Jing, Liu, Yinghua, Powers, Alvin C., Kim, Seung K.
Published in Cell metabolism (03.02.2015)
Published in Cell metabolism (03.02.2015)
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Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development
Duvall, Eliza, Benitez, Cecil M, Tellez, Krissie, Enge, Martin, Pauerstein, Philip T, Li, Lingyu, Baek, Songjoon, Quake, Stephen R, Smith, Jason P, Sheffield, Nathan C, Kim, Seung K, Arda, H Efsun
Published in Proceedings of the National Academy of Sciences - PNAS (28.06.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (28.06.2022)
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Neonatal β Cell Development in Mice and Humans Is Regulated by Calcineurin/NFAT
Goodyer, William R., Gu, Xueying, Liu, Yinghua, Bottino, Rita, Crabtree, Gerald R., Kim, Seung K.
Published in Developmental cell (17.07.2012)
Published in Developmental cell (17.07.2012)
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Discovering human diabetes-risk gene function with genetics and physiological assays
Peiris, Heshan, Park, Sangbin, Louis, Shreya, Gu, Xueying, Lam, Jonathan Y., Asplund, Olof, Ippolito, Gregory C., Bottino, Rita, Groop, Leif, Tucker, Haley, Kim, Seung K.
Published in Nature communications (21.09.2018)
Published in Nature communications (21.09.2018)
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Molecular and genetic regulation of pig pancreatic islet cell development
Kim, Seokho, Whitener, Robert L, Peiris, Heshan, Gu, Xueying, Chang, Charles A, Lam, Jonathan Y, Camunas-Soler, Joan, Park, Insung, Bevacqua, Romina J, Tellez, Krissie, Quake, Stephen R, Lakey, Jonathan R T, Bottino, Rita, Ross, Pablo J, Kim, Seung K
Published in Development (Cambridge) (30.03.2020)
Published in Development (Cambridge) (30.03.2020)
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Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells
Lee, Jonghyeob, Snyder, Emily R., Liu, Yinghua, Gu, Xueying, Wang, Jing, Flowers, Brittany M., Kim, Yoo Jung, Park, Sangbin, Szot, Gregory L., Hruban, Ralph H., Longacre, Teri A., Kim, Seung K.
Published in Nature communications (08.03.2017)
Published in Nature communications (08.03.2017)
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CRISPR-based genome editing in primary human pancreatic islet cells
Bevacqua, Romina J., Dai, Xiaoqing, Lam, Jonathan Y., Gu, Xueying, Friedlander, Mollie S. H., Tellez, Krissie, Miguel-Escalada, Irene, Bonàs-Guarch, Silvia, Atla, Goutham, Zhao, Weichen, Kim, Seung Hyun, Dominguez, Antonia A., Qi, Lei S., Ferrer, Jorge, MacDonald, Patrick E., Kim, Seung K.
Published in Nature communications (23.04.2021)
Published in Nature communications (23.04.2021)
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US–Guided, Direct Puncture Retrograde Thoracic Duct Access, Lymphangiography, and Embolization: Feasibility and Efficacy
Guevara, Carlos J., MD, Rialon, Kristy L., MD, Ramaswamy, Raja S., MD, Kim, Seung K., MD, Darcy, Michael D., MD
Published in Journal of vascular and interventional radiology (01.12.2016)
Published in Journal of vascular and interventional radiology (01.12.2016)
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Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells
Lee, Jonghyeob, Sugiyama, Takuya, Liu, Yinghua, Wang, Jing, Gu, Xueying, Lei, Ji, Markmann, James F, Miyazaki, Satsuki, Miyazaki, Jun-Ichi, Szot, Gregory L, Bottino, Rita, Kim, Seung K
Published in eLife (19.11.2013)
Published in eLife (19.11.2013)
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NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
Graef, Isabella A, Crabtree, Gerald R, Arron, Joseph R, Winslow, Monte M, Polleri, Alberto, Chang, Ching-Pin, Wu, Hai, Gao, Xin, Neilson, Joel R, Chen, Lei, Heit, Jeremy J, Kim, Seung K, Yamasaki, Nobuyuki, Miyakawa, Tsuyoshi, Francke, Uta
Published in Nature (01.06.2006)
Published in Nature (01.06.2006)
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