Design and synthesis of 4th generation EGFR inhibitors against human triple (Del19/T790M/C797S) mutation
Jeon, Jiyoung, Jang, Sun Young, Kwak, Eun Joo, Lee, Sun Hoe, Byun, Joo-Yun, Kim, Yu-Yon, Ahn, Young Gil, Singh, Pargat, Moon, Kyeongwon, Kim, In Su
Published in European journal of medicinal chemistry (05.12.2023)
Published in European journal of medicinal chemistry (05.12.2023)
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Journal Article
HM71224, a selective Bruton's tyrosine kinase inhibitor, attenuates the development of murine lupus
Kim, Yu-Yon, Park, Ki Tae, Jang, Sun Young, Lee, Kyu Hang, Byun, Joo-Yun, Suh, Kwee Hyun, Lee, Young-Mi, Kim, Young Hoon, Hwang, Kwang Woo
Published in Arthritis research & therapy (26.09.2017)
Published in Arthritis research & therapy (26.09.2017)
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Journal Article
HM71224, a novel Bruton's tyrosine kinase inhibitor, suppresses B cell and monocyte activation and ameliorates arthritis in a mouse model: a potential drug for rheumatoid arthritis
Park, Jin Kyun, Byun, Joo-Yun, Park, Ji Ah, Kim, Yu-Yon, Lee, Ye Ji, Oh, Jeong In, Jang, Sun Young, Kim, Young Hoon, Song, Yeong Wook, Son, Jeewoong, Suh, Kwee Hyun, Lee, Young-Mi, Lee, Eun Bong
Published in Arthritis research & therapy (18.04.2016)
Published in Arthritis research & therapy (18.04.2016)
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Journal Article
Belvarafenib penetrates the BBB and shows potent antitumor activity in a murine melanoma brain metastasis model
Kim, Yu-Yon, Park, Hyunjin, Song, Taehun, Choi, Kyungjin, Dolton, Michael, Mao, Jialin, Kim, Jisook, Ahn, Young Gil, Suh, Kwee Hyun, Kim, Young Hoon
Published in Clinical & experimental metastasis (01.04.2023)
Published in Clinical & experimental metastasis (01.04.2023)
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Journal Article
Eflapegrastim's enhancement of efficacy compared with pegfilgrastim in neutropenic rats supports potential for same-day dosing
Barrett, John A, Choi, Jaehyuk, Lakshmikanthan, Sribalaji, Kim, Yu-Yon, Greene, Douglas, Kolli, Prasad, Song, Tae Hun, Choi, In Young, Kim, Young Hoon, Lebel, Francois
Published in Experimental hematology (01.12.2020)
Published in Experimental hematology (01.12.2020)
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Journal Article
Abstract 1142: A novel and potent EZH1/2 dual inhibitor, HM97662, demonstrates antitumor activity in malignant tumors
Jung, Seung Hyun, Hong, DongJin, Hwang, Jiyoung, Park, Somin, Byun, Jooyun, Lee, Miyoung, Koo, Kyounghwa, Lee, Gunwoo, Kim, Yu-Yon, Bak, Yesol, Ahn, Young Gil, Kim, YoungHoon, Suh, Kwee Hyun
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel FMS inhibitors
Kim, Yu-Yon, Choi, Jaeyul, Choi, Kyungjin, Park, Changhee, Kim, Young Hoon, Suh, Kwee Hyun, Ham, Young Jin, Jang, Sun Young, Lee, Kyu-Hang, Hwang, Kwang Woo
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
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Journal Article
A Novel and Potent EZH1/2 Dual Inhibitor HM97594 for the Treatment of Hematological Malignancies
Jung, Seung Hyun, Hong, DongJin, Kim, SeoHee, Hwang, Jiyoung, Byun, Jooyun, Lee, Miyoung, Koo, Kyounghwa, Lee, Gunwoo, Song, TaeHun, Lim, SunYoung, Kim, Yu-Yon, Park, Hyunjin, Bak, Yesol, Ko, Myoungsil, Jung, Sunyoung, Han, Yuri, Ahn, YoungGil, Kim, YoungHoon, Suh, KweeHyun
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
ANTIGENIC PEPTIDE HAVING MULTIPLE KRAS VARIANT PEPTIDES LINKED THERETO, NUCLEIC ACID ENCODING THE SAME, AND USE THEREOF
SHIN, Seung Hyun, LIM, Chang Gyu, JEONG, Seong Ju, KIM, Yu Yon, LEE, Ji Hee, HEO, Yong Ho, KIM, Inn Ah, DONG, Joo Young, HAN, Young Jin
Year of Publication 27.06.2024
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Year of Publication 27.06.2024
Patent
NOVEL IMMUNOACTIVE INTERLEUKIN 2 ANALOG CONJUGATE AND METHOD FOR PREPARING SAME
KIM, Jin Young, KIM, Sang Yun, PARK, Jun Sub, OH, Euh Lim, PARK, Da Hyeon, LEE, A Ram, HEO, Yong Ho, KIM, Yu Yon
Year of Publication 06.10.2022
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Year of Publication 06.10.2022
Patent
A Novel and Potent EZH1/2 Dual Inhibitor, HM97662 Demonstrated a Wide Spectrum of Therapeutic Potential for Hematological Malignancies
Jung, Seung Hyun, Byun, Jooyun, Kim, Yu-Yon, Han, Seon Yeong, Lee, Miyoung, Lee, Gunwoo, Park, Junghwa, Ahn, Young Gil, Kim, Young Hoon, Suh, Kwee Hyun, Koh, Youngil
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Abstract CT116: Same-day administration of Eflapegrastim with chemotherapy enhances neutropenic recovery in neutropenic rats and in early-stage breast cancer patients
Barrett, John A., Chawla, Shanta, Kolli, Prasad S., Kim, Yu- Yon, Lakshmikanthan, Sri, Tugnait, Meera, Dreiling, Lyndah K., Lebel, Francois
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 2044: Chemotherapy induced neutropenia in rats following administration of eflapegrastim or pegfilgrastim on the same day at three different timepoints and at 24 hours post-chemotherapy
Kim, Yu-Yon, Kim, Eunjung, Han, Hyesun, Baek, Seungjae, Chawla, Shanta, Kolli, Prasad, Bhat, Gajanan, Lebel, Francois
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 1257: HM43239, a novel FLT3 inhibitor, has the potential to inhibit mutations resistant to FLT3 inhibitors
Bae, Inhwan, Choi, Jaeyul, Song, Jiyoung, Byun, Joo-Yun, Lee, Eunyoung, Song, Taehun, Kim, Yu-Yon, Bak, Yesol, Kim, Young Hoon, Ahn, Young Gil, Suh, Kwee Hyun
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 1704: Discovery and characterization of a novel triple A1/A2a/A2b adenosine receptor antagonist for cancer immunotherapy
Jang, Sunyoung, Jun, Seunah, Lee, Hosun, Lee, Yongtaek, Byun, Joo-Yun, Park, Junghwa, Kim, Yu-Yon, Ahn, Young Gil, Kim, YoungHoon, Suh, Kwee Hyun
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 1474: Antitumor activity of belvarafenib in melanoma brain metastasis and NRAS mutation melanoma models
Bae, Inhwan, Kim, Yu-Yon, Kim, Jisook, Park, Hyunjin, Song, Taehyun, Byun, Joo-Yun, Lim, Semi, Kim, Young Hoon, Ahn, Young Gil, Suh, Kwee Hyun
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 1135: Antitumor activity of novel reversible LSD1 inhibitors in preclinical models of AML and SCLC
Byun, Joo-Yun, Lee, Won Jong, Kim, Won jung, Kim, Minjeong, Bae, Inhwan, Hong, Seokhyun, Kim, Yu-Yon, Park, Hyunjin, Kim, Eunyoung, Kim, Young Hoon, Ahn, Young Gil, Suh, Kwee Hyun
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 1831: A long-acting and CD122-enhanced IL-2 analog, HM16390, synergizes with immune checkpoint inhibitor by remodeling an immune cell profile in tumor microenvironment
Choi, Jaehyuk, Kim, Jinyoung, Kim, Yu Yon, Jeong, Seongju, Bae, Sungmin, Kim, Daejin, Choi, In Young
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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