Molecular Determinants of Dofetilide Block of HERG K+ Channels
Ficker, Eckhard, Jarolimek, Wolfgang, Kiehn, Johann, Baumann, Arnd, Brown, Arthur M
Published in Circulation research (23.02.1998)
Published in Circulation research (23.02.1998)
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The antipsychotic drug chlorpromazine inhibits HERG potassium channels
Thomas, Dierk, Wu, Kezhong, Kathöfer, Sven, Katus, Hugo A, Schoels, Wolfgang, Kiehn, Johann, Karle, Christoph A
Published in British journal of pharmacology (01.06.2003)
Published in British journal of pharmacology (01.06.2003)
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Deletion of Protein Kinase A Phosphorylation Sites in the HERG Potassium Channel Inhibits Activation Shift by Protein Kinase A
Thomas, Dierk, Zhang, Wei, Karle, Christoph A., Kathöfer, Sven, Schöls, Wolfgang, Kübler, Wolfgang, Kiehn, Johann
Published in The Journal of biological chemistry (24.09.1999)
Published in The Journal of biological chemistry (24.09.1999)
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High-Affinity Blockade of Human Ether-A-Go-Go-Related Gene Human Cardiac Potassium Channels by the Novel Antiarrhythmic Drug BRL-32872
Thomas, D, Wendt-Nordahl, G, Röckl, K, Ficker, E, Brown, A M, Kiehn, J
Published in The Journal of pharmacology and experimental therapeutics (01.05.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.2001)
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Inhibition of cardiac HERG channels by grapefruit flavonoid naringenin: implications for the influence of dietary compounds on cardiac repolarisation
Scholz, Eberhard P, Zitron, Edgar, Kiesecker, Claudia, Lück, Sonja, Thomas, Dierk, Kathöfer, Sven, Kreye, Volker A W, Katus, Hugo A, Kiehn, Johann, Schoels, Wolfgang, Karle, Christoph A
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.06.2005)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.06.2005)
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Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone
Zitron, Edgar, Kiesecker, Claudia, Scholz, Eberhard, Lück, Sonja, Bloehs, Ramona, Kathöfer, Sven, Thomas, Dierk, Kiehn, Johann, Kreye, Volker A W, Katus, Hugo A, Schoels, Wolfgang, Karle, Christoph A
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.08.2004)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.08.2004)
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Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine
Scholz, Eberhard P, Zitron, Edgar, Kiesecker, Claudia, Lueck, Sonja, Kathöfer, Sven, Thomas, Dierk, Weretka, Slawomir, Peth, Simon, Kreye, Volker A W, Schoels, Wolfgang, Katus, Hugo A, Kiehn, Johann, Karle, Christoph A
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.11.2003)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.11.2003)
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Comparison of Binding and Block Produced by Alternatively Spliced Kvβ1 Subunits
Wang, Zhiguo, Kiehn, Johann, Yang, Qing, Brown, Arthur M., Wible, Barbara A.
Published in The Journal of biological chemistry (01.11.1996)
Published in The Journal of biological chemistry (01.11.1996)
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Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by ?1A-adrenoceptors
Thomas, Dierk, Wu, Kezhong, Wimmer, Anna-Britt, Zitron, Edgar, Hammerling, Bettina C., Kath fer, Sven, Lueck, Sonja, Bloehs, Ramona, Kreye, Volker A. W., Kiehn, Johann, Katus, Hugo A., Schoels, Wolfgang, Karle, Christoph A.
Published in Journal of molecular medicine (Berlin, Germany) (01.12.2004)
Published in Journal of molecular medicine (Berlin, Germany) (01.12.2004)
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Human ?3-adrenoreceptors couple to KvLQT1/MinK potassium channels in Xenopus oocytes via protein kinase C phosphorylation of the KvLQT1 protein
Kath fer, Sven, R ckl, Katja, Zhang, Wei, Thomas, Dierk, Katus, Hugo, Kiehn, Johann, Kreye, Volker, Schoels, Wolfgang, Karle, Christoph
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.08.2003)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.08.2003)
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Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing
THOMAS, Dierk, KIEHN, Johann, KATUS, Hugo A, KARLE, Christoph A
Published in Cardiovascular research (01.11.2003)
Published in Cardiovascular research (01.11.2003)
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QTc prolongation by grapefruit juice and its potential pharmacological basis: HERG channel blockade by flavonoids
ZITRON, Edgar, SCHOLZ, Eberhard, KATUS, Hugo A, SCHOELS, Wolfgang, KARLE, Christoph A, OWEN, Robert W, LÜCK, Sonja, KIESECKER, Claudia, THOMAS, Dierk, KATHÖFER, Sven, NIROOMAND, Feraydoon, KIEHN, Johann, KREYE, Volker A. W
Published in Circulation (New York, N.Y.) (22.02.2005)
Published in Circulation (New York, N.Y.) (22.02.2005)
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Journal Article
Doxazosin induces apoptosis of cells expressing hERG K + channels
Thomas, Dierk, Bloehs, Ramona, Koschny, Ronald, Ficker, Eckhard, Sykora, Jaromir, Kiehn, Johann, Schlömer, Kathrin, Gierten, Jakob, Kathöfer, Sven, Zitron, Edgar, Scholz, Eberhard P., Kiesecker, Claudia, Katus, Hugo A., Karle, Christoph A.
Published in European journal of pharmacology (28.01.2008)
Published in European journal of pharmacology (28.01.2008)
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Human cardiac inwardly rectifying current IKir2.2 is upregulated by activation of protein kinase A
ZITRON, Edgar, KIESECKER, Claudia, LÜCK, Sonja, KATHÖFER, Sven, THOMAS, Dierk, KREYE, Volker A. W, KIEHN, Johann, KATUS, Hugo A, SCHOELS, Wolfgang, KARLE, Christoph A
Published in Cardiovascular research (15.08.2004)
Published in Cardiovascular research (15.08.2004)
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Journal Article
Molecular physiology and pharmacology of HERG : Single-channel currents and block by dofetilide
KIEHN, J, LACERDA, A. E, WIBLE, B, BROWN, A. M
Published in Circulation (New York, N.Y.) (15.11.1996)
Published in Circulation (New York, N.Y.) (15.11.1996)
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Human cardiac inwardly-rectifying K+ channel Kir2.1b is inhibited by direct protein kinase C-dependent regulation in human isolated cardiomyocytes and in an expression system
KARLE, Christoph A, ZITRON, Edgar, KIEHN, Johann, WEI ZHANG, WENDT-NORDAHL, Gunnar, KATHÖFER, Sven, THOMAS, Dierk, GUT, Bernd, SCHOLZ, Eberhard, VAHL, Christian-Friedrich, KATUS, Hugo A
Published in Circulation (New York, N.Y.) (17.09.2002)
Published in Circulation (New York, N.Y.) (17.09.2002)
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