First-in-human study of a liver-directed AAV gene therapy (FLT190) in Fabry disease
Hughes, Derralynn A., Patel, Niten, Kinch, Russell, Dronfield, Leanne, Short, Gerard, Sheridan, Rose, Kia, Azadeh, Jeyakumar, Jey, Corbau, Romuald, Nathwani, Amit
Published in Molecular genetics and metabolism (01.02.2020)
Published in Molecular genetics and metabolism (01.02.2020)
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Journal Article
Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA
Gueranger, Quentin, Kia, Azadeh, Frith, David, Karran, Peter
Published in Nucleic acids research (01.07.2011)
Published in Nucleic acids research (01.07.2011)
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Journal Article
Preclinical evaluation of FLT190, a liver-directed AAV gene therapy for Fabry disease
Jeyakumar, Jey M., Kia, Azadeh, Tam, Lawrence C. S., McIntosh, Jenny, Spiewak, Justyna, Mills, Kevin, Heywood, Wendy, Chisari, Elisa, Castaldo, Noemi, Verhoef, Daniël, Hosseini, Paniz, Kalcheva, Petya, Cocita, Clement, Miranda, Carlos J., Canavese, Miriam, Khinder, Jaminder, Rosales, Cecilia, Hughes, Derralynn, Sheridan, Rose, Corbau, Romuald, Nathwani, Amit
Published in Gene therapy (01.06.2023)
Published in Gene therapy (01.06.2023)
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Journal Article
ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2
Pedrini, Steve, Sau, Daniela, Guareschi, Stefania, Bogush, Marina, Brown, Robert H., Naniche, Nicole, Kia, Azadeh, Trotti, Davide, Pasinelli, Piera
Published in Human molecular genetics (01.08.2010)
Published in Human molecular genetics (01.08.2010)
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Journal Article
폴리뉴클레오티드
CORBAU ROMUALD, KIA AZADEH, FOLEY JONATHAN, CORREIA SAMANTHA, CANAVESE MIRIAM
Year of Publication 24.02.2023
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Year of Publication 24.02.2023
Patent
Efficacy Evaluation of Liver-Directed Gene Therapy in Fabry Mice
Kia, Azadeh, McIntosh, Jenny, Rosales, Cecilia, Hosseini, Paniz, Sheridan, Rose, Spiewak, Justyna, Mills, Kevin, Corbau, Romuald, Nathwani, Amit C
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
인자 VIII 폴리펩타이드
CORBAU ROMUALD, KIA AZADEH, COMPER FABRIZIO, DODEV TIHOMIR, MCINTOSH JENNY
Year of Publication 01.07.2022
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Year of Publication 01.07.2022
Patent
폴리뉴클레오티드
CORBAU ROMUALD, MIRANDA CARLOS, KIA AZADEH, NATHWANI AMIT, MCINTOSH JENNY
Year of Publication 07.12.2021
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Year of Publication 07.12.2021
Patent
Liver-directed gene therapy corrects Fabry disease in mice
Jeyakumar, Jey, Kia, Azadeh, McIntosh, Jenny, Verhoef, Daniel, Kalcheva, Petya, Hosseini, Paniz, Sheridan, Rose, Corbau, Romuald, Nathwani, Amit
Published in Molecular genetics and metabolism (01.02.2019)
Published in Molecular genetics and metabolism (01.02.2019)
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Journal Article
Liver-Directed AAV Gene Therapy for Gaucher Disease
Miranda, Carlos J, Canavese, Miriam, Chisari, Elisa, Pandya, Jalpa, Cocita, Clement, Portillo, Maria, McIntosh, Jenny, Kia, Azadeh, Foley, Jonathan H., Dane, Allison, Jeyakumar, Jey M, Sheridan, Rose, Corbau, Romuald, Nathwani, Amit C.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
폴리펩티드
CORBAU ROMUALD, MIRANDA CARLOS, KIA AZADEH, COMPER FABRIZIO, NATHWANI AMIT, MCINTOSH JENNY
Year of Publication 28.03.2023
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Year of Publication 28.03.2023
Patent
Preferential targeting of disseminated liver tumors using a recombinant adeno-associated viral vector
Della Peruta, Marco, Badar, Adam, Rosales, Cecilia, Chokshi, Shilpa, Kia, Azadeh, Nathwani, Devhrut, Galante, Eva, Yan, Ran, Arstad, Erik, Davidoff, Andrew M, Williams, Roger, Lythgoe, Mark F, Nathwani, Amit C
Published in Human gene therapy (01.02.2015)
Published in Human gene therapy (01.02.2015)
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Journal Article
Liver directed AAV gene therapy to treat Gaucher disease
Miranda, Carlos J., McIntosh, Jenny, Kia, Azadeh, Canavese, Miriam, Foley, Jonathan, Lee, Doyoung, Hosseini, Paniz, Jeyakumar, Jey, Sheridan, Rose, Corbau, Romuald, Nathwani, Amit C.
Published in Molecular genetics and metabolism (01.02.2019)
Published in Molecular genetics and metabolism (01.02.2019)
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Journal Article
One-off liver directed AAV gene therapy achieves long term uptake of acid beta-glucocerebrosidase by macrophages of affected tissues in Gaucher disease
Miranda, Carlos J., Chisari, Elisa, Northcott, Natalie, Pandya, Jalpa, Liou, Benjamin, Fannin, Venette, Blackwood, Rachel, Dane, Allison, Kia, Azadeh, Canavese, Miriam, Khinder, Jaminder, Sheridan, Rose, Sun, Ying, Corbau, Romuald, Nathwani, Amit C.
Published in Molecular genetics and metabolism (01.02.2020)
Published in Molecular genetics and metabolism (01.02.2020)
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Journal Article
Design and Characterization of FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate
Kia, Azadeh, Comper, Fabrizio, Correia, Samantha, Casari, Caterina, Negash, Segen, Portillo, Maria, Pandya, Jalpa, Dodev, Tihomir, Schulze, Andreas, Sonntag, Florian, Kober, Renee, Cocita, Clement, Chisari, Elisa, Alade, Rebecca, Shehu, Erald, Jeyakumar, Jey M, Khinder, Jaminder, Foley, Jonathan H., Dane, Allison, McIntosh, Jenny, Ollerton, Hattie, Christophe, Olivier, Denis, Cecile V., Corbau, Romuald
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Conference Proceeding