Chemistry and Biology of Resveratrol-Derived Natural Products
Keylor, Mitchell H, Matsuura, Bryan S, Stephenson, Corey R. J
Published in Chemical reviews (09.09.2015)
Published in Chemical reviews (09.09.2015)
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Journal Article
Photocatalytic initiation of thiol–ene reactions: synthesis of thiomorpholin-3-ones
Keylor, Mitchell H., Park, James E., Wallentin, Carl-Johan, Stephenson, Corey R.J.
Published in Tetrahedron (08.07.2014)
Published in Tetrahedron (08.07.2014)
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Journal Article
Synthesis of resveratrol tetramers via a stereoconvergent radical equilibrium
Keylor, Mitchell H., Matsuura, Bryan S., Griesser, Markus, Chauvin, Jean-Philippe R., Harding, Ryan A., Kirillova, Mariia S., Zhu, Xu, Fischer, Oliver J., Pratt, Derek A., Stephenson, Corey R. J.
Published in Science (American Association for the Advancement of Science) (09.12.2016)
Published in Science (American Association for the Advancement of Science) (09.12.2016)
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Leveraging the Persistent Radical Effect in the Synthesis of trans‐2,3‐Diaryl Dihydrobenzofurans
Roldan, Bec J., Hammerstad, Travis A., Galliher, Matthew S., Keylor, Mitchell H., Pratt, Derek A., Stephenson, Corey R. J.
Published in Angewandte Chemie International Edition (21.08.2023)
Published in Angewandte Chemie International Edition (21.08.2023)
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Journal Article
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors
Keylor, Mitchell H, Gulati, Anmol, Kattar, Solomon D, Johnson, Rebecca E, Chau, Ryan W, Margrey, Kaila A, Ardolino, Michael J, Zarate, Cayetana, Poremba, Kelsey E, Simov, Vladimir, Morriello, Gregori J, Acton, John J, Pio, Barbara, Yan, Xin, Palte, Rachel L, McMinn, Spencer E, Nogle, Lisa, Lesburg, Charles A, Adpressa, Donovon, Lin, Shishi, Neelamkavil, Santhosh, Liu, Ping, Su, Jing, Hegde, Laxminarayan G, Woodhouse, Janice D, Faltus, Robert, Xiong, Tina, Ciaccio, Paul J, Piesvaux, Jennifer, Otte, Karin M, Wood, Harold B, Kennedy, Matthew E, Bennett, David Jonathan, DiMauro, Erin F, Fell, Matthew J, Fuller, Peter H
Published in Journal of medicinal chemistry (13.01.2022)
Published in Journal of medicinal chemistry (13.01.2022)
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Journal Article
A Scalable Biomimetic Synthesis of Resveratrol Dimers and Systematic Evaluation of their Antioxidant Activities
Matsuura, Bryan S., Keylor, Mitchell H., Li, Bo, Lin, YuXuan, Allison, Shelby, Pratt, Derek A., Stephenson, Corey R. J.
Published in Angewandte Chemie (International ed.) (16.03.2015)
Published in Angewandte Chemie (International ed.) (16.03.2015)
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Journal Article
Discovery and Optimization of N‑Heteroaryl Indazole LRRK2 Inhibitors
Logan, Kaitlyn M., Kaplan, Will, Simov, Vladimir, Zhou, Hua, Li, Derun, Torres, Luis, Morriello, Gregori J., Acton, John J., Pio, Barbara, Chen, Yi-Heng, Keylor, Mitchell H., Johnson, Rebecca, Kattar, Solomon D., Chau, Ryan, Yan, Xin, Ardolino, Michael, Zarate, Cayetana, Otte, Karin M., Palte, Rachel L., Xiong, Tina, McMinn, Spencer E., Lin, Shishi, Neelamkavil, Santhosh F., Liu, Ping, Su, Jing, Hegde, Laxminarayan G., Woodhouse, Janice D., Moy, Lily Y., Ciaccio, Paul J., Piesvaux, Jennifer, Zebisch, Matthias, Henry, Clare, Barker, John, Wood, Harold B., Kennedy, Matthew E., DiMauro, Erin F., Fell, Matthew J., Fuller, Peter H.
Published in Journal of medicinal chemistry (26.09.2024)
Published in Journal of medicinal chemistry (26.09.2024)
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Journal Article
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease
Kattar, Solomon D., Gulati, Anmol, Margrey, Kaila A., Keylor, Mitchell H., Ardolino, Michael, Yan, Xin, Johnson, Rebecca, Palte, Rachel L., McMinn, Spencer E., Nogle, Lisa, Su, Jing, Xiao, Dong, Piesvaux, Jennifer, Lee, Susi, Hegde, Laxminarayan G., Woodhouse, Janice D., Faltus, Robert, Moy, Lily Y., Xiong, Tina, Ciaccio, Paul J., Pearson, Kara, Patel, Mayankbhai, Otte, Karin M., Leyns, Cheryl E.G., Kennedy, Matthew E., Bennett, David Jonathan, DiMauro, Erin F., Fell, Matthew J., Fuller, Peter H.
Published in Journal of medicinal chemistry (09.11.2023)
Published in Journal of medicinal chemistry (09.11.2023)
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Journal Article
LRRK2 억제제로서의 N-연결된 이소퀴놀린 아미드, 제약 조성물 및 그의 용도
FULLER PETER H, YAN XIN, GULATI ANMOL, MARGREY KAILA A, KATTAR SOLOMON D, KEYLOR MITCHELL H
Year of Publication 30.06.2023
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Year of Publication 30.06.2023
Patent
A Scalable Biomimetic Synthesis of Resveratrol Dimers and Systematic Evaluation of their Antioxidant Activities
Matsuura, Bryan S., Keylor, Mitchell H., Li, Bo, Lin, YuXuan, Allison, Shelby, Pratt, Derek A., Stephenson, Corey R. J.
Published in Angewandte Chemie (16.03.2015)
Published in Angewandte Chemie (16.03.2015)
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Journal Article
LRRK2 억제제로서의 N- 퀴나졸린-2-아민 유도체, 제약 조성물 및 그의 용도
FULLER PETER H, YU ELSIE C, GULATI ANMOL, JOHNSON REBECCA ELIZABETH, CHAU RYAN W, NEELAMKAVIL SANTHOSH F, KEYLOR MITCHELL H, MORRIELLO GREGORI J, YAN XIN, MARGREY KAILA A, ZARATE SAEZ CAYETANA CARMELA, ARDOLINO MICHAEL J, KATTAR SOLOMON D
Year of Publication 28.06.2022
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Year of Publication 28.06.2022
Patent
Efficient synthesis for each of the eight stereoisomers of the iminosugars lentiginosine and 1,4-dideoxy-1,4-imino-D-arabinitol (DAB)
Liotta, Louis J., Antoine, Jessica, Brammer Basta, Leighanne A., Campbell, Andrew S., Cole, Gabrielle Y., Demick Brazile, Kristen A., Dogal Gardner, Natalie M., Fitzgerald, Megan E., Francois, Jean E.K., French, Brian M., Garafola, Sara L., Giannetti, Catherine A., Granatosky, Eve A., Harney, Alycen M., Hummel, James T., Joyce, Andrew P., Keylor, Mitchell H., Khubchandani, Jasmine A., Korzeniecki, Claudia, Lieberman, Diana C., Litterio, Joshua M., Maiorano, Madison O., Marshall, Jessica F., McCarthy, Kelly A., Mendes Vieira, Andreia, Miller, Ruby M., Morrison, Emily R., Moura, Steven P., Neumann, Dillon F., Oliveira, Aliza F., Pace, Nicholas J., Plouffe, Jodie X., Pomfret, Meredith N., Reardon, Katelyn N., Sheller-Miller, Samantha M., Smith, Michael J., Sullivan, Jessica L., Sweeney, Samantha W., Tougas, Kerstin L.
Published in Carbohydrate research (01.11.2024)
Published in Carbohydrate research (01.11.2024)
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Journal Article
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1‑Heteroaryl‑1H‑Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease
Candito, David A., Simov, Vladimir, Gulati, Anmol, Kattar, Solomon, Chau, Ryan W., Lapointe, Blair T., Methot, Joey L., DeMong, Duane E., Graham, Thomas H., Kurukulasuriya, Ravi, Keylor, Mitchell H., Tong, Ling, Morriello, Gregori J., Acton, John J., Pio, Barbara, Liu, Weiguo, Scott, Jack D., Ardolino, Michael J., Martinot, Theodore A., Maddess, Matthew L., Yan, Xin, Gunaydin, Hakan, Palte, Rachel L., McMinn, Spencer E., Nogle, Lisa, Yu, Hongshi, Minnihan, Ellen C., Lesburg, Charles A., Liu, Ping, Su, Jing, Hegde, Laxminarayan G., Moy, Lily Y., Woodhouse, Janice D., Faltus, Robert, Xiong, Tina, Ciaccio, Paul, Piesvaux, Jennifer A., Otte, Karin M., Kennedy, Matthew E., Bennett, David Jonathan, DiMauro, Erin F., Fell, Matthew J., Neelamkavil, Santhosh, Wood, Harold B., Fuller, Peter H., Ellis, J. Michael
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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Journal Article
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1 H -Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease
Candito, David A, Simov, Vladimir, Gulati, Anmol, Kattar, Solomon, Chau, Ryan W, Lapointe, Blair T, Methot, Joey L, DeMong, Duane E, Graham, Thomas H, Kurukulasuriya, Ravi, Keylor, Mitchell H, Tong, Ling, Morriello, Gregori J, Acton, John J, Pio, Barbara, Liu, Weiguo, Scott, Jack D, Ardolino, Michael J, Martinot, Theodore A, Maddess, Matthew L, Yan, Xin, Gunaydin, Hakan, Palte, Rachel L, McMinn, Spencer E, Nogle, Lisa, Yu, Hongshi, Minnihan, Ellen C, Lesburg, Charles A, Liu, Ping, Su, Jing, Hegde, Laxminarayan G, Moy, Lily Y, Woodhouse, Janice D, Faltus, Robert, Xiong, Tina, Ciaccio, Paul, Piesvaux, Jennifer A, Otte, Karin M, Kennedy, Matthew E, Bennett, David Jonathan, DiMauro, Erin F, Fell, Matthew J, Neelamkavil, Santhosh, Wood, Harold B, Fuller, Peter H, Ellis, J Michael
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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Journal Article
N-LINKED ISOQUINOLINE AMIDES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF
Fuller, Peter H, Keylor, Mitchell H, Yan, Xin, Margrey, Kaila A, Gulati, Anmol, Kattar, Solomon D
Year of Publication 21.12.2023
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Year of Publication 21.12.2023
Patent