Mechanistic biomarkers provide early and sensitive detection of acetaminophen‐induced acute liver injury at first presentation to hospital
Antoine, Daniel J., Dear, James W., Lewis, Philip Starkey, Platt, Vivien, Coyle, Judy, Masson, Moyra, Thanacoody, Ruben H., Gray, Alasdair J., Webb, David J., Moggs, Jonathan G., Bateman, D. Nicholas, Goldring, Christopher E., Park, B. Kevin
Published in Hepatology (Baltimore, Md.) (01.08.2013)
Published in Hepatology (Baltimore, Md.) (01.08.2013)
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Journal Article
Circulating microRNAs as potential markers of human drug‐induced liver injury
Starkey Lewis, Philip J., Dear, James, Platt, Vivien, Simpson, Kenneth J., Craig, Darren G.N., Antoine, Daniel J., French, Neil S., Dhaun, Neeraj, Webb, David J., Costello, Eithne M., Neoptolemos, John P., Moggs, Jonathan, Goldring, Chris E., Park, B. Kevin
Published in Hepatology (Baltimore, Md.) (01.11.2011)
Published in Hepatology (Baltimore, Md.) (01.11.2011)
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Journal Article
Alternatively activated macrophages promote resolution of necrosis following acute liver injury
Starkey Lewis, Philip, Campana, Lara, Aleksieva, Niya, Cartwright, Jennifer Ann, Mackinnon, Alison, O'Duibhir, Eoghan, Kendall, Timothy, Vermeren, Matthieu, Thomson, Adrian, Gadd, Victoria, Dwyer, Benjamin, Aird, Rhona, Man, Tak-Yung, Rossi, Adriano Giorgio, Forrester, Lesley, Park, B. Kevin, Forbes, Stuart John
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
Dapsone‐ and nitroso dapsone‐specific activation of T cells from hypersensitive patients expressing the risk allele HLA‐B13:01
Zhao, Qing, Alhilali, Khetam, Alzahrani, Abdulaziz, Almutairi, Mubarak, Amjad, Juwaria, Liu, Hong, Sun, Yonghu, Sun, Lele, Zhang, Huimin, Meng, Xiaoli, Gibson, Andrew, Ogese, Monday O., Kevin Park, B., Liu, Jianjun, Ostrov, David A., Zhang, Furen, Naisbitt, Dean J.
Published in Allergy (Copenhagen) (01.08.2019)
Published in Allergy (Copenhagen) (01.08.2019)
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Journal Article
Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes
Sabbisetti, Venkata S, Waikar, Sushrut S, Antoine, Daniel J, Smiles, Adam, Wang, Chang, Ravisankar, Abinaya, Ito, Kazumi, Sharma, Sahil, Ramadesikan, Swetha, Lee, Michelle, Briskin, Rebeccah, De Jager, Philip L, Ngo, Thanh Thu, Radlinski, Mark, Dear, James W, Park, Kevin B, Betensky, Rebecca, Krolewski, Andrzej S, Bonventre, Joseph V
Published in Journal of the American Society of Nephrology (01.10.2014)
Published in Journal of the American Society of Nephrology (01.10.2014)
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Journal Article
Immune pathomechanism of drug hypersensitivity reactions
Pichler, Werner J., MD, Naisbitt, Dean J., PhD, Park, B. Kevin, PhD
Published in Journal of allergy and clinical immunology (01.03.2011)
Published in Journal of allergy and clinical immunology (01.03.2011)
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Journal Article
Conference Proceeding
The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity
Kamalian, Laleh, Douglas, Oisin, Jolly, Carol E., Snoeys, Jan, Simic, Damir, Monshouwer, Mario, Williams, Dominic P., Kevin Park, B., Chadwick, Amy E.
Published in Toxicology in vitro (01.12.2018)
Published in Toxicology in vitro (01.12.2018)
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Journal Article
Human leukocyte antigen (HLA)‐B57:01‐restricted activation of drug‐specific T cells provides the immunological basis for flucloxacillin‐induced liver injury
Monshi, Manal M., Faulkner, Lee, Gibson, Andrew, Jenkins, Rosalind E., Farrell, John, Earnshaw, Caroline J., Alfirevic, Ana, Cederbrant, Karin, Daly, Ann K., French, Neil, Pirmohamed, Munir, Park, B. Kevin, Naisbitt, Dean J.
Published in Hepatology (Baltimore, Md.) (01.02.2013)
Published in Hepatology (Baltimore, Md.) (01.02.2013)
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Journal Article
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation
Xue, Mingzhan, Rabbani, Naila, Momiji, Hiroshi, Imbasi, Precious, Anwar, M Maqsud, Kitteringham, Neil, Park, B Kevin, Souma, Tomokazu, Moriguchi, Takashi, Yamamoto, Masayuki, Thornalley, Paul J
Published in Biochemical journal (01.04.2012)
Published in Biochemical journal (01.04.2012)
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Journal Article
Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics
Kitteringham, Neil R., Jenkins, Rosalind E., Lane, Catherine S., Elliott, Victoria L., Park, B. Kevin
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.05.2009)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.05.2009)
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Journal Article
Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile
Heslop, James A., Rowe, Cliff, Walsh, Joanne, Sison-Young, Rowena, Jenkins, Roz, Kamalian, Laleh, Kia, Richard, Hay, David, Jones, Robert P., Malik, Hassan Z., Fenwick, Stephen, Chadwick, Amy E., Mills, John, Kitteringham, Neil R., Goldring, Chris E. P., Kevin Park, B.
Published in Archives of toxicology (01.01.2017)
Published in Archives of toxicology (01.01.2017)
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Journal Article
Mass Spectrometric and Functional Aspects of Drug–Protein Conjugation
Tailor, Arun, Waddington, James C, Meng, Xiaoli, Park, B. Kevin
Published in Chemical research in toxicology (19.12.2016)
Published in Chemical research in toxicology (19.12.2016)
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Journal Article
Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress
Mutter, Fiona E, Park, B Kevin, Copple, Ian M
Published in Biochemical Society transactions (01.08.2015)
Published in Biochemical Society transactions (01.08.2015)
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Journal Article
Characterization of amoxicillin‐ and clavulanic acid‐specific T cells in patients with amoxicillin‐clavulanate–induced liver injury
Kim, Seung‐Hyun, Saide, Katy, Farrell, John, Faulkner, Lee, Tailor, Arun, Ogese, Monday, Daly, Ann K., Pirmohamed, Munir, Park, B. Kevin, Naisbitt, Dean J.
Published in Hepatology (Baltimore, Md.) (01.09.2015)
Published in Hepatology (Baltimore, Md.) (01.09.2015)
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Journal Article
Assessing the Safety of Stem Cell Therapeutics
Goldring, Chris E.P., Duffy, Paul A., Benvenisty, Nissim, Andrews, Peter W., Ben-David, Uri, Eakins, Rowena, French, Neil, Hanley, Neil A., Kelly, Lorna, Kitteringham, Neil R., Kurth, Jens, Ladenheim, Deborah, Laverty, Hugh, McBlane, James, Narayanan, Gopalan, Patel, Sara, Reinhardt, Jens, Rossi, Annamaria, Sharpe, Michaela, Park, B. Kevin
Published in Cell stem cell (03.06.2011)
Published in Cell stem cell (03.06.2011)
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Journal Article
Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients
Meng, Xiaoli, Al-Attar, Zaid, Yaseen, Fiazia S, Jenkins, Rosalind, Earnshaw, Caroline, Whitaker, Paul, Peckham, Daniel, French, Neil S, Naisbitt, Dean J, Park, B Kevin
Published in The Journal of immunology (1950) (01.06.2017)
Published in The Journal of immunology (1950) (01.06.2017)
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Journal Article
Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy
Lister, Adam, Nedjadi, Taoufik, Kitteringham, Neil R, Campbell, Fiona, Costello, Eithne, Lloyd, Bryony, Copple, Ian M, Williams, Samantha, Owen, Andrew, Neoptolemos, John P, Goldring, Chris E, Park, B Kevin
Published in Molecular cancer (13.04.2011)
Published in Molecular cancer (13.04.2011)
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