Target engagement and drug residence time can be observed in living cells with BRET
Robers, Matthew B., Dart, Melanie L., Woodroofe, Carolyn C., Zimprich, Chad A., Kirkland, Thomas A., Machleidt, Thomas, Kupcho, Kevin R., Levin, Sergiy, Hartnett, James R., Zimmerman, Kristopher, Niles, Andrew L., Ohana, Rachel Friedman, Daniels, Danette L., Slater, Michael, Wood, Monika G., Cong, Mei, Cheng, Yi-Qiang, Wood, Keith V.
Published in Nature communications (03.12.2015)
Published in Nature communications (03.12.2015)
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Journal Article
Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological induction
Jaskula-Sztul, Renata, Eide, Jacob, Tesfazghi, Sara, Dammalapati, Ajitha, Harrison, April D, Yu, Xiao-Min, Scheinebeck, Casi, Winston-McPherson, Gabrielle, Kupcho, Kevin R, Robers, Matthew B, Hundal, Amrit K, Tang, Weiping, Chen, Herbert
Published in Molecular cancer therapeutics (01.02.2015)
Published in Molecular cancer therapeutics (01.02.2015)
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Journal Article
The Androgen Receptor T877A Mutant Recruits LXXLL and FXXLF Peptides Differently than Wild-Type Androgen Receptor in a Time-Resolved Fluorescence Resonance Energy Transfer Assay
Ozers, Mary Szatkowski, Marks, Bryan D, Gowda, Krishne, Kupcho, Kevin R, Ervin, Kerry M, De Rosier, Therese, Qadir, Naveeda, Eliason, Hildegard C, Riddle, Steven M, Shekhani, Mohammed Saleh
Published in Biochemistry (Easton) (23.01.2007)
Published in Biochemistry (Easton) (23.01.2007)
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The Couette configuration of the Los Alamos Neutron Science Center neutron rheometer for the investigation of polymers in the bulk via small-angle neutron scattering
Yearley, Eric J, Sasa, Leslie A, Welch, Cynthia F, Taylor, Mark A, Kupcho, Kevin M, Gilbertson, Robert D, Hjelm, Rex P
Published in Review of scientific instruments (01.04.2010)
Published in Review of scientific instruments (01.04.2010)
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A homogeneous, nonradioactive high-throughput fluorogenic protein kinase assay
Kupcho, Kevin, Somberg, Richard, Bulleit, Bob, Goueli, Said A
Published in Analytical biochemistry (15.06.2003)
Published in Analytical biochemistry (15.06.2003)
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Journal Article
Overcoming compound interference in fluorescence polarization-based kinase assays using far-red tracers
Vedvik, Kevin L, Eliason, Hildegard C, Hoffman, Randy L, Gibson, Jasmin R, Kupcho, Kevin R, Somberg, Richard L, Vogel, Kurt W
Published in Assay and drug development technologies (01.04.2004)
Published in Assay and drug development technologies (01.04.2004)
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Abstract 1933: Improved DAMP assays for the in vitro assessment of immunogenic cell death
Niles, Andrew L., Kupcho, Kevin R., Lazar, Dan F., Cali, James J.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
A real-time, bioluminescent annexin V assay for the assessment of apoptosis
Kupcho, Kevin, Shultz, John, Hurst, Robin, Hartnett, Jim, Zhou, Wenhui, Machleidt, Thomas, Grailer, Jamison, Worzella, Tracy, Riss, Terry, Lazar, Dan, Cali, James J., Niles, Andrew
Published in Apoptosis (London) (01.02.2019)
Published in Apoptosis (London) (01.02.2019)
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Characterization of Phosphotyrosine Binding Motifs in the Cytoplasmic Domain of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Are Required for the Cellular Association and Activation of the Protein-tyrosine Phosphatase, SHP-2
Jackson, Denise E., Kupcho, Kevin R., Newman, Peter. J.
Published in The Journal of biological chemistry (03.10.1997)
Published in The Journal of biological chemistry (03.10.1997)
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Journal Article
Lumit&[trade] Immunoassays for Simple and Rapid Determination of Cytokine Release from Cell Culture Models
Lazar, Dan F, Hsiao, Kevin, Sondgeroth, Casey, Gilden, Julia, Kupcho, Kevin, Thompson, David, O’Brien, Martha, Cali, James
Published in The Journal of immunology (1950) (01.05.2021)
Published in The Journal of immunology (1950) (01.05.2021)
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Abstract 710: Real-time apoptosis and necrosis detection in 3D spheroid cellmodels
Niles, Andrew L., Kupcho, Kevin R., Riss, Terry L., Lazar, Dan F., Cali, James J.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 1112: Detection ofHMGB1 and extracellular ATP for the assessment of immunogenic cell death
Somberg, Richard L., Kupcho, Kevin, Niles, Andrew, Cali, James
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 5595: Rapid and sensitive determination of cytokine release from cells without the need for sample transfer
Lazar, Dan F., Kupcho, Kevin R., Sondgeroth, Casey A., Thompson, David V., O'Brien, Martha A., Gilden, Julia K., Hsiao, Kevin, Cali, James J.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Rapid and sensitive determination of cytokine release from cells without the need for sample transfer
Lazar, Dan F, Kupcho, Kevin R, Sondgeroth, Casey A, Hsiao, Kevin, Thompson, David V, O’Brien, Martha A, Gilden, Julia K, Cali, James J
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
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