Validation of the Essential ClpP Protease in Mycobacterium tuberculosis as a Novel Drug Target
Ollinger, Juliane, O'Malley, Theresa, Kesicki, Edward A, Odingo, Joshua, Parish, Tanya
Published in Journal of Bacteriology (01.02.2012)
Published in Journal of Bacteriology (01.02.2012)
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Journal Article
Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents
Kesicki, Edward A, Bailey, Mai A, Ovechkina, Yulia, Early, Julie V, Alling, Torey, Bowman, Julie, Zuniga, Edison S, Dalai, Suryakanta, Kumar, Naresh, Masquelin, Thierry, Hipskind, Philip A, Odingo, Joshua O, Parish, Tanya
Published in PloS one (12.05.2016)
Published in PloS one (12.05.2016)
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Epinephrine inhibits PI3Kα via the Hippo kinases
Lin, Ting-Yu, Ramsamooj, Shakti, Perrier, Tiffany, Liberatore, Katarina, Lantier, Louise, Vasan, Neil, Karukurichi, Kannan, Hwang, Seo-Kyoung, Kesicki, Edward A., Kastenhuber, Edward R., Wiederhold, Thorsten, Yaron, Tomer M., Huntsman, Emily M., Zhu, Mengmeng, Ma, Yilun, Paddock, Marcia N., Zhang, Guoan, Hopkins, Benjamin D., McGuinness, Owen, Schwartz, Robert E., Ersoy, Baran A., Cantley, Lewis C., Johnson, Jared L., Goncalves, Marcus D.
Published in Cell reports (Cambridge) (26.12.2023)
Published in Cell reports (Cambridge) (26.12.2023)
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A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis
Kumar, Anuradha, Casey, Allen, Odingo, Joshua, Kesicki, Edward A, Abrahams, Garth, Vieth, Michal, Masquelin, Thierry, Mizrahi, Valerie, Hipskind, Philip A, Sherman, David R, Parish, Tanya
Published in PloS one (07.11.2013)
Published in PloS one (07.11.2013)
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Journal Article
DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs
SHINOHARA, Eric T, LING GENG, JIAHUI TAN, HEIDI CHEN, YU SHIR, EDWARDS, Eric, HALBROOK, James, KESICKI, Edward A, KASHISHIAN, Adam, HALLAHAN, Dennis E
Published in Cancer research (Chicago, Ill.) (15.06.2005)
Published in Cancer research (Chicago, Ill.) (15.06.2005)
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Journal Article
DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer
Kashishian, Adam, Douangpanya, Heather, Clark, Darcey, Schlachter, Stephen T, Eary, C Todd, Schiro, Justin G, Huang, Hongmei, Burgess, Larry E, Kesicki, Edward A, Halbrook, James
Published in Molecular cancer therapeutics (01.12.2003)
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Published in Molecular cancer therapeutics (01.12.2003)
Journal Article
Phenylboronic Acid−Salicylhydroxamic Acid Bioconjugates. 1. A Novel Boronic Acid Complex for Protein Immobilization
Stolowitz, Mark L, Ahlem, Clarence, Hughes, Karin A, Kaiser, Robert J, Kesicki, Edward A, Li, Guisheng, Lund, Kevin P, Torkelson, Steven M, Wiley, Jean P
Published in Bioconjugate chemistry (01.03.2001)
Published in Bioconjugate chemistry (01.03.2001)
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Journal Article
Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome
Weinert, Brian T., Narita, Takeo, Satpathy, Shankha, Srinivasan, Balaji, Hansen, Bogi K., Schölz, Christian, Hamilton, William B., Zucconi, Beth E., Wang, Wesley W., Liu, Wenshe R., Brickman, Joshua M., Kesicki, Edward A., Lai, Albert, Bromberg, Kenneth D., Cole, Philip A., Choudhary, Chunaram
Published in Cell (28.06.2018)
Published in Cell (28.06.2018)
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Journal Article
Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases
Ji, Zhiqin, Clark, Richard F., Bhat, Vikram, Matthew Hansen, T., Lasko, Loren M., Bromberg, Kenneth D., Manaves, Vlasios, Algire, Mikkel, Martin, Ruth, Qiu, Wei, Torrent, Maricel, Jakob, Clarissa G., Liu, Hong, Cole, Philip A., Marmorstein, Ronen, Kesicki, Edward A., Lai, Albert, Michaelides, Michael R.
Published in Bioorganic & medicinal chemistry letters (01.05.2021)
Published in Bioorganic & medicinal chemistry letters (01.05.2021)
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Journal Article
Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases
Michaelides, Michael R, Kluge, Arthur, Patane, Michael, Van Drie, John H, Wang, Ce, Hansen, T. Matthew, Risi, Roberto M, Mantei, Robert, Hertel, Carmen, Karukurichi, Kannan, Nesterov, Alexandre, McElligott, David, de Vries, Peter, Langston, J. William, Cole, Philip A, Marmorstein, Ronen, Liu, Hong, Lasko, Loren, Bromberg, Kenneth D, Lai, Albert, Kesicki, Edward A
Published in ACS medicinal chemistry letters (11.01.2018)
Published in ACS medicinal chemistry letters (11.01.2018)
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Journal Article
Synthesis and evaluation of the 2,4-diaminoquinazoline series as anti-tubercular agents
Odingo, Joshua, O’Malley, Theresa, Kesicki, Edward A., Alling, Torey, Bailey, Mai Ann, Early, Julie, Ollinger, Juliane, Dalai, Suryakanta, Kumar, Naresh, Singh, Ravindra Vikram, Hipskind, Philip A., Cramer, Jeffrey W., Ioerger, Thomas, Sacchettini, James, Vickers, Richard, Parish, Tanya
Published in Bioorganic & medicinal chemistry (15.12.2014)
Published in Bioorganic & medicinal chemistry (15.12.2014)
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Journal Article
Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
Lasko, Loren M., Jakob, Clarissa G., Edalji, Rohinton P., Qiu, Wei, Montgomery, Debra, Digiammarino, Enrico L., Hansen, T. Matt, Risi, Roberto M., Frey, Robin, Manaves, Vlasios, Shaw, Bailin, Algire, Mikkel, Hessler, Paul, Lam, Lloyd T., Uziel, Tamar, Faivre, Emily, Ferguson, Debra, Buchanan, Fritz G., Martin, Ruth L., Torrent, Maricel, Chiang, Gary G., Karukurichi, Kannan, Langston, J. William, Weinert, Brian T., Choudhary, Chunaram, de Vries, Peter, Kluge, Arthur F., Patane, Michael A., Van Drie, John H., Wang, Ce, McElligott, David, Kesicki, Edward A., Marmorstein, Ronen, Sun, Chaohong, Cole, Philip A., Rosenberg, Saul H., Michaelides, Michael R., Lai, Albert, Bromberg, Kenneth D.
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
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Journal Article
Identification of ring-fused pyrazolo pyridin-2-ones as novel poly(ADP-ribose)polymerase-1 inhibitors
Moree, Wilna J., Goldman, Phyllis, Demaggio, Anthony J., Christenson, Erik, Herendeen, Dan, Eksterowicz, John, Kesicki, Edward A., McElligott, David L., Beaton, Graham
Published in Bioorganic & medicinal chemistry (15.09.2008)
Published in Bioorganic & medicinal chemistry (15.09.2008)
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Journal Article
A specific antagonist of the p110δ catalytic component of phosphatidylinositol 3'-kinase, IC486068, enhances radiation-induced tumor vascular destruction
LING GENG, JIAHUAI TAN, HALLAHAN, Dennis E, HIMMELFARB, Eric, SCHUENEMAN, Aaron, NIERMANN, Ken, FU, Allie, CUNEO, Kyle, KESICKI, Edward A, TREIBERG, Jennifer, HAYFLICK, Joel S
Published in Cancer research (Chicago, Ill.) (15.07.2004)
Published in Cancer research (Chicago, Ill.) (15.07.2004)
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암의 치료를 위한 포스포이노시티드 3-키나제 (PI3K)의 알로스테릭 크로메논 억제제
DAWADI SURENDRA, WIDJAJA TIEN, LONG KATELYN FRANCES, ARONOW SEAN DOUGLAS, KNIGHT JENNIFER LYNN, KOLAKOWSKI GABRIELLE R, WANG HUA YU, ANDERSON ERIN DANIELLE, HICKEY EUGENE R, IRVIN THOMAS COMBS, MCLEAN JOHNATHAN ALEXANDER, WELCH MICHAEL BRIAN, MAYNE CHRISTOPHER GLENN, KUMAR MANOJ, CHEN XIAOHONG, BOYLES NICHOLAS A, POTOTSCHNIG GERIT MARIA, KESICKI EDWARD A
Year of Publication 31.01.2024
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Year of Publication 31.01.2024
Patent
질환의 치료를 위한 포스포이노시티드 3-키나제 (PI3K)의 알로스테릭 크로메논 억제제
DAWADI SURENDRA, PICADO ALFREDO, WIDJAJA TIEN, LONG KATELYN FRANCES, ARONOW SEAN DOUGLAS, KNIGHT JENNIFER LYNN, KOLAKOWSKI GABRIELLE R, WANG HUA YU, ANDERSON ERIN DANIELLE, HICKEY EUGENE R, WRIGHT NATHAN EDWARD, IRVIN THOMAS COMBS, WELCH MICHAEL BRIAN, MAYNE CHRISTOPHER GLENN, KUMAR MANOJ, CHEN XIAOHONG, BOYLES NICHOLAS A, POTOTSCHNIG GERIT MARIA, KESICKI EDWARD A
Year of Publication 11.01.2024
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Year of Publication 11.01.2024
Patent
질환의 치료를 위한 포스포이노시티드 3-키나제 (PI3K)의 알로스테릭 크로메논 억제제
DAWADI SURENDRA, PICADO ALFREDO, WIDJAJA TIEN, LONG KATELYN FRANCES, ARONOW SEAN DOUGLAS, KNIGHT JENNIFER LYNN, KOLAKOWSKI GABRIELLE R, WANG HUA YU, ANDERSON ERIN DANIELLE, HICKEY EUGENE R, WRIGHT NATHAN EDWARD, IRVIN THOMAS COMBS, WELCH MICHAEL BRIAN, MAYNE CHRISTOPHER GLENN, KUMAR MANOJ, CHEN XIAOHONG, BOYLES NICHOLAS A, POTOTSCHNIG GERIT MARIA, KESICKI EDWARD A
Year of Publication 11.01.2024
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Year of Publication 11.01.2024
Patent