Validation of the Essential ClpP Protease in Mycobacterium tuberculosis as a Novel Drug Target
Ollinger, Juliane, O'Malley, Theresa, Kesicki, Edward A, Odingo, Joshua, Parish, Tanya
Published in Journal of Bacteriology (01.02.2012)
Published in Journal of Bacteriology (01.02.2012)
Get full text
Journal Article
Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents
Kesicki, Edward A, Bailey, Mai A, Ovechkina, Yulia, Early, Julie V, Alling, Torey, Bowman, Julie, Zuniga, Edison S, Dalai, Suryakanta, Kumar, Naresh, Masquelin, Thierry, Hipskind, Philip A, Odingo, Joshua O, Parish, Tanya
Published in PloS one (12.05.2016)
Published in PloS one (12.05.2016)
Get full text
Journal Article
A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis
Kumar, Anuradha, Casey, Allen, Odingo, Joshua, Kesicki, Edward A, Abrahams, Garth, Vieth, Michal, Masquelin, Thierry, Mizrahi, Valerie, Hipskind, Philip A, Sherman, David R, Parish, Tanya
Published in PloS one (07.11.2013)
Published in PloS one (07.11.2013)
Get full text
Journal Article
Epinephrine inhibits PI3Kα via the Hippo kinases
Lin, Ting-Yu, Ramsamooj, Shakti, Perrier, Tiffany, Liberatore, Katarina, Lantier, Louise, Vasan, Neil, Karukurichi, Kannan, Hwang, Seo-Kyoung, Kesicki, Edward A., Kastenhuber, Edward R., Wiederhold, Thorsten, Yaron, Tomer M., Huntsman, Emily M., Zhu, Mengmeng, Ma, Yilun, Paddock, Marcia N., Zhang, Guoan, Hopkins, Benjamin D., McGuinness, Owen, Schwartz, Robert E., Ersoy, Baran A., Cantley, Lewis C., Johnson, Jared L., Goncalves, Marcus D.
Published in Cell reports (Cambridge) (26.12.2023)
Published in Cell reports (Cambridge) (26.12.2023)
Get full text
Journal Article
Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome
Weinert, Brian T., Narita, Takeo, Satpathy, Shankha, Srinivasan, Balaji, Hansen, Bogi K., Schölz, Christian, Hamilton, William B., Zucconi, Beth E., Wang, Wesley W., Liu, Wenshe R., Brickman, Joshua M., Kesicki, Edward A., Lai, Albert, Bromberg, Kenneth D., Cole, Philip A., Choudhary, Chunaram
Published in Cell (28.06.2018)
Published in Cell (28.06.2018)
Get full text
Journal Article
Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases
Ji, Zhiqin, Clark, Richard F., Bhat, Vikram, Matthew Hansen, T., Lasko, Loren M., Bromberg, Kenneth D., Manaves, Vlasios, Algire, Mikkel, Martin, Ruth, Qiu, Wei, Torrent, Maricel, Jakob, Clarissa G., Liu, Hong, Cole, Philip A., Marmorstein, Ronen, Kesicki, Edward A., Lai, Albert, Michaelides, Michael R.
Published in Bioorganic & medicinal chemistry letters (01.05.2021)
Published in Bioorganic & medicinal chemistry letters (01.05.2021)
Get full text
Journal Article
Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases
Michaelides, Michael R, Kluge, Arthur, Patane, Michael, Van Drie, John H, Wang, Ce, Hansen, T. Matthew, Risi, Roberto M, Mantei, Robert, Hertel, Carmen, Karukurichi, Kannan, Nesterov, Alexandre, McElligott, David, de Vries, Peter, Langston, J. William, Cole, Philip A, Marmorstein, Ronen, Liu, Hong, Lasko, Loren, Bromberg, Kenneth D, Lai, Albert, Kesicki, Edward A
Published in ACS medicinal chemistry letters (11.01.2018)
Published in ACS medicinal chemistry letters (11.01.2018)
Get full text
Journal Article
Synthesis and evaluation of the 2,4-diaminoquinazoline series as anti-tubercular agents
Odingo, Joshua, O’Malley, Theresa, Kesicki, Edward A., Alling, Torey, Bailey, Mai Ann, Early, Julie, Ollinger, Juliane, Dalai, Suryakanta, Kumar, Naresh, Singh, Ravindra Vikram, Hipskind, Philip A., Cramer, Jeffrey W., Ioerger, Thomas, Sacchettini, James, Vickers, Richard, Parish, Tanya
Published in Bioorganic & medicinal chemistry (15.12.2014)
Published in Bioorganic & medicinal chemistry (15.12.2014)
Get full text
Journal Article
DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs
SHINOHARA, Eric T, LING GENG, JIAHUI TAN, HEIDI CHEN, YU SHIR, EDWARDS, Eric, HALBROOK, James, KESICKI, Edward A, KASHISHIAN, Adam, HALLAHAN, Dennis E
Published in Cancer research (Chicago, Ill.) (15.06.2005)
Published in Cancer research (Chicago, Ill.) (15.06.2005)
Get full text
Journal Article
Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
Lasko, Loren M, Jakob, Clarissa G, Edalji, Rohinton P, Qiu, Wei, Montgomery, Debra, Digiammarino, Enrico L, Hansen, T Matt, Risi, Roberto M, Frey, Robin, Manaves, Vlasios, Shaw, Bailin, Algire, Mikkel, Hessler, Paul, Lam, Lloyd T, Uziel, Tamar, Faivre, Emily, Ferguson, Debra, Buchanan, Fritz G, Martin, Ruth L, Torrent, Maricel, Chiang, Gary G, Karukurichi, Kannan, Langston, J William, Weinert, Brian T, Choudhary, Chunaram, de Vries, Peter, Kluge, Arthur F, Patane, Michael A, Van Drie, John H, Wang, Ce, McElligott, David, Kesicki, Edward A, Marmorstein, Ronen, Sun, Chaohong, Cole, Philip A, Rosenberg, Saul H, Michaelides, Michael R, Lai, Albert, Bromberg, Kenneth D
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
Get full text
Journal Article
DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer
Kashishian, Adam, Douangpanya, Heather, Clark, Darcey, Schlachter, Stephen T, Eary, C Todd, Schiro, Justin G, Huang, Hongmei, Burgess, Larry E, Kesicki, Edward A, Halbrook, James
Published in Molecular cancer therapeutics (01.12.2003)
Get full text
Published in Molecular cancer therapeutics (01.12.2003)
Journal Article
Phenylboronic Acid−Salicylhydroxamic Acid Bioconjugates. 1. A Novel Boronic Acid Complex for Protein Immobilization
Stolowitz, Mark L, Ahlem, Clarence, Hughes, Karin A, Kaiser, Robert J, Kesicki, Edward A, Li, Guisheng, Lund, Kevin P, Torkelson, Steven M, Wiley, Jean P
Published in Bioconjugate chemistry (01.03.2001)
Published in Bioconjugate chemistry (01.03.2001)
Get full text
Journal Article
Identification of ring-fused pyrazolo pyridin-2-ones as novel poly(ADP-ribose)polymerase-1 inhibitors
Moree, Wilna J., Goldman, Phyllis, Demaggio, Anthony J., Christenson, Erik, Herendeen, Dan, Eksterowicz, John, Kesicki, Edward A., McElligott, David L., Beaton, Graham
Published in Bioorganic & medicinal chemistry (15.09.2008)
Published in Bioorganic & medicinal chemistry (15.09.2008)
Get full text
Journal Article
A specific antagonist of the p110δ catalytic component of phosphatidylinositol 3'-kinase, IC486068, enhances radiation-induced tumor vascular destruction
LING GENG, JIAHUAI TAN, HALLAHAN, Dennis E, HIMMELFARB, Eric, SCHUENEMAN, Aaron, NIERMANN, Ken, FU, Allie, CUNEO, Kyle, KESICKI, Edward A, TREIBERG, Jennifer, HAYFLICK, Joel S
Published in Cancer research (Chicago, Ill.) (15.07.2004)
Published in Cancer research (Chicago, Ill.) (15.07.2004)
Get full text
Journal Article
Phenylboronic Acid−Salicylhydroxamic Acid Bioconjugates. 2. Polyvalent Immobilization of Protein Ligands for Affinity Chromatography
Wiley, Jean P, Hughes, Karin A, Kaiser, Robert J, Kesicki, Edward A, Lund, Kevin P, Stolowitz, Mark L
Published in Bioconjugate chemistry (01.03.2001)
Published in Bioconjugate chemistry (01.03.2001)
Get full text
Journal Article
Abstract P142: Preclinical characterization of LOX-22783, a highly potent, mutant-selective and brain-penetrant allosteric PI3Kα H1047R inhibitor
Klippel, Anke, Wang, Rui, Puca, Loredana, Faber, Andrew Lee, Shen, Weihua, Bhagwat, Shripad V., Karukurichi, Kannan, Zhang, Feiyu Fred, Perez, Carmen, Rama, Ramon, Ramos, Ana, Zheng, Yi, Bonday, Zahid, Thomas, James, Brooks, Harold B., Kindler, Lisa J., Bogner, Sarah M., Zolfaghari, Parisa, II, Mark Hicks, Callies, Sophie, Mattioni, Brian, LeBrun, Laurie, Durbin, Jim, Anderson, Erin, Mayne, Chris, Kesicki, Edward, Kolakowski, Gabrielle, Andrews, Steven W., Brandhuber, Barbara J.
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
Get full text
Journal Article
Development of Inhibitors of PIP4K2 As a Treatment for Patients with Hematologic Malignancies
McElligott, David L, Kesicki, Edward, Karukarichi, Kannan, Shim, Hyeseok, Wang, Rui, Yu, Albert S., Zolfaghari, Parisa, Linstrom, Johan, Persson, Lars, Hoglund, Andreas, Ericsson, Ulrika, Trésaugues, Lionel, Livendahl, Madeleine, Santangelo, Ellen, Viklund, Jenny, Pettersson, Mariell, Wähling, Horst, Forsblom, Rickard, Karlsson, Fredrik, Ginman, Tobias, Braga, Tiago, Henley, Aine Brigette, Talagas, Antoine, Rahm, Fredrik, Johansson, Tommy, Martinsson, Jessica, Andersson, Martin, Cantley, Lewis
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
Get full text
Journal Article