Design Principles for Fragment Libraries: Maximizing the Value of Learnings from Pharma Fragment-Based Drug Discovery (FBDD) Programs for Use in Academia
Keserű, György M, Erlanson, Daniel A, Ferenczy, György G, Hann, Michael M, Murray, Christopher W, Pickett, Stephen D
Published in Journal of medicinal chemistry (22.09.2016)
Published in Journal of medicinal chemistry (22.09.2016)
Get full text
Journal Article
A covalent strategy to target intrinsically disordered proteins: Discovery of novel tau aggregation inhibitors
Petri, László, Ábrányi-Balogh, Péter, Vagrys, Darius, Imre, Tímea, Varró, Nikolett, Mándity, István, Rácz, Anita, Wittner, Lucia, Tóth, Kinga, Tóth, Estilla Zsófia, Juhász, Tünde, Davis, Ben, Keserű, György Miklós
Published in European journal of medicinal chemistry (05.03.2022)
Published in European journal of medicinal chemistry (05.03.2022)
Get full text
Journal Article
Exploring protein hotspots by optimized fragment pharmacophores
Bajusz, Dávid, Wade, Warren S., Satała, Grzegorz, Bojarski, Andrzej J., Ilaš, Janez, Ebner, Jessica, Grebien, Florian, Papp, Henrietta, Jakab, Ferenc, Douangamath, Alice, Fearon, Daren, von Delft, Frank, Schuller, Marion, Ahel, Ivan, Wakefield, Amanda, Vajda, Sándor, Gerencsér, János, Pallai, Péter, Keserű, György M.
Published in Nature communications (27.05.2021)
Published in Nature communications (27.05.2021)
Get full text
Journal Article
Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease
Godoy, Andre Schutzer, Nakamura, Aline Minalli, Douangamath, Alice, Song, Yun, Noske, Gabriela Dias, Gawriljuk, Victor Oliveira, Fernandes, Rafaela Sachetto, Pereira, Humberto D Muniz, Oliveira, Ketllyn Irene Zagato, Fearon, Daren, Dias, Alexandre, Krojer, Tobias, Fairhead, Michael, Powell, Alisa, Dunnet, Louise, Brandao-Neto, Jose, Skyner, Rachael, Chalk, Rod, Bajusz, Dávid, Bege, Miklós, Borbás, Anikó, Keserű, György Miklós, von Delft, Frank, Oliva, Glaucius
Published in Nucleic acids research (09.06.2023)
Published in Nucleic acids research (09.06.2023)
Get full text
Journal Article
Activation-Free Sulfonyl Fluoride Probes for Fragment Screening
Petri, László, Ábrányi-Balogh, Péter, Csorba, Noémi, Keeley, Aaron, Simon, József, Ranđelović, Ivan, Tóvári, József, Schlosser, Gitta, Szabó, Dániel, Drahos, László, Keserű, György M
Published in Molecules (Basel, Switzerland) (29.03.2023)
Published in Molecules (Basel, Switzerland) (29.03.2023)
Get full text
Journal Article
Virtual Fragment Docking by Glide: a Validation Study on 190 Protein−Fragment Complexes
Sándor, Márk, Kiss, Róbert, Keserű, György M
Published in Journal of chemical information and modeling (28.06.2010)
Published in Journal of chemical information and modeling (28.06.2010)
Get full text
Journal Article
Discovery of Immunoproteasome Inhibitors Using Large-Scale Covalent Virtual Screening
Scarpino, Andrea, Bajusz, Dávid, Proj, Matic, Gobec, Martina, Sosič, Izidor, Gobec, Stanislav, Ferenczy, György G, Keserű, György M
Published in Molecules (Basel, Switzerland) (16.07.2019)
Published in Molecules (Basel, Switzerland) (16.07.2019)
Get full text
Journal Article
Fingerprint-Based Machine Learning Approach to Identify Potent and Selective 5-HT2BR Ligands
Rataj, Krzysztof, Kelemen, Ádám, Brea, José, Loza, María, Bojarski, Andrzej, Keserű, György
Published in Molecules (Basel, Switzerland) (10.05.2018)
Published in Molecules (Basel, Switzerland) (10.05.2018)
Get full text
Journal Article
Thermodynamics of Fragment Binding
Ferenczy, György G, Keserű, György M
Published in Journal of chemical information and modeling (23.04.2012)
Published in Journal of chemical information and modeling (23.04.2012)
Get full text
Journal Article
Comparative evaluation of pK(a) prediction tools on a drug discovery dataset
Balogh, György T, Tarcsay, Akos, Keserű, György M
Published in Journal of pharmaceutical and biomedical analysis (01.08.2012)
Published in Journal of pharmaceutical and biomedical analysis (01.08.2012)
Get full text
Journal Article
Positive allosteric modulators for mGluR2 receptors: a medicinal chemistry perspective
Szabó, György, Keserű, György Miklós
Published in Current topics in medicinal chemistry (01.01.2014)
Published in Current topics in medicinal chemistry (01.01.2014)
Get more information
Journal Article
Enthalpic Efficiency of Ligand Binding
Ferenczy, György G, Keserű, György M
Published in Journal of chemical information and modeling (27.09.2010)
Published in Journal of chemical information and modeling (27.09.2010)
Get full text
Journal Article